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01.03.2017 | main topic | Ausgabe 3-4/2017

Wiener Medizinische Wochenschrift 3-4/2017

Radiation-induced lichen sclerosus of the vulva

First report in the medical literature

Wiener Medizinische Wochenschrift > Ausgabe 3-4/2017
Dr. Lisa R. Edwards, Dr. Emily D. Privette, MD Prof. Dr. James W. Patterson, Prof. Georgi Tchernev, Dr. Anastasiya Atanasova Chokoeva, Prof. Dr. Uwe Wollina, MD, MD (Hon) Prof. Dr. Torello Lotti, Dr. Barbara B. Wilson


A 67-year-old woman presented with a firm plaque in the perineal region, 16 months after diagnosis of a high-grade basaloid squamous cell carcinoma of the vagina and treatment by external beam radiation therapy and vaginal cuff brachytherapy. The differential diagnosis included radiation-induced morphea, radiation dermatitis, or, possibly, radiation-induced lichen sclerosus. Biopsy findings, including special staining, confirmed the diagnosis of radiation-induced lichen sclerosus. To our knowledge, this is the first report of radiation-induced lichen sclerosus of the vulvar region.

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