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01.08.2013 | Original Article | Ausgabe 4/2013

European Surgery 4/2013

Quality of life in type 2 diabetics with gastroesophageal reflux disease: a case control study

Zeitschrift:
European Surgery > Ausgabe 4/2013
Autoren:
R. Promberger, A. Spitzer, J. Ott, J. Lenglinger, W. Eilenberg, M. Gadenstätter, C. Neumayer

Summary

Background

To compare health- and disease-related quality of life (QoL) in patients with gastroesophageal reflux disease (GERD), with and without type 2 diabetes mellitus (T2DM).

Methods

In a retro-pro study of 29 non-diabetic and 30 diabetic GERD-patients who underwent complete esophageal testing because of GERD symptoms, three different QoL questionnaires [short-form 36 (SF-36) questionnaire, Gastrointestinal Quality of Life Index (GIQLI), GERD-health related QoL Index (GERD-HRQL)] and a standardized symptom questionnaire were analyzed.

Results

T2DM patients revealed higher body-mass-index levels (31.8 ± 6.3 vs. 28.2 ± 4.4 kg/m2, p = 0.004), whereas hiatal hernias were found less frequently in non-diabetics (82.8 vs. 32.1 %, p < 0.001). Lower esophageal sphincter pressures (LES) were higher in T2DM GERD-patients (11.1 ± 6.1 vs. 5.3 ± 4.0 mmHg; p < 0.001). In the SF-36 domains, “vitality” and “physical functioning,” T2DM patients revealed lower QoL (48.8 ± 20.3 vs. 60.0 ± 16.7, p = 0.023; and 64.7 ± 25.4 vs. 78.8 ± 19.8, p = 0.027; respectively). The GERD-HRQL (16.8 ± 13.1 vs. 18.8 ± 10.7, p > 0.05) and GIQLI (88.5 ± 25.1 vs. 94.0 ± 18.2, p  > 0.05) did not differ significantly.

Conclusions

T2DM had a major impact on health-related QoL in patients with proven GERD, with impairment of the SF-36 domains, “physical functioning” and “vitality”. GERD-specific QoL, however, was similar in diabetic and non-diabetic patients.

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