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Wiener klinische Wochenschrift

Erschienen in:

01.01.2013 | original article

Prognostic significance of lymph node characteristics on survival in esophageal squamous cell carcinomas

verfasst von: Ning Wu, MD, Zhiming Chen, MD, Liewen Pang, MD, Qinyun Ma, Gang Chen

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 1-2/2013

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Summary

Objectives

To investigate the prognostic significance of lymph node characteristics (total number of resected lymph nodes, metastatic lymph node ratio, and metastatic lymph nodes site) on survival in patients with esophageal squamous cell carcinoma.

Methods

Patients who underwent esophagectomy at Huashan Hospital, Fudan University, between October 1, 2003, and December 31, 2008, were reviewed. Survival data and clinicopathological characteristics were collected.

Results

Among 205 patients, the median overall survival time was 48.0 months and the overall 5-year survival rate was 44.7 %. The independent risk factors for disease-free survival were the metastatic lymph node ratio (P < 0.001) and the number of positive lymph nodes (P < 0.001) and not the total number of resected lymph nodes (Χ ² = 3.063, P = 0.216). There was no difference in survival between patients with extrathoracic and intrathoracic lymph node metastasis (Χ ² = 0.295, P = 0.587). No significant relation was found between tumor location and the site of metastatic lymph nodes (rs = 0.125, P = 0.245).

Conclusions

Our finding revealed that the ratio and the number, but not the site, of metastatic lymph nodes were independent prognostic risk factors in esophageal squamous cell carcinomas. We suggest taking these factors into consideration for better estimation of prognosis.

Vorheriger Artikel The usefulness of ulcer size and location in the differential diagnosis of benign and malignant gastric ulcer

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Titel: Prognostic significance of lymph node characteristics on survival in esophageal squamous cell carcinomas
verfasst von: Ning Wu, MD
Zhiming Chen, MD
Liewen Pang, MD
Qinyun Ma
Gang Chen
Publikationsdatum: 01.01.2013
Verlag: Springer Vienna
Erschienen in: Wiener klinische Wochenschrift / Ausgabe 1-2/2013
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI: https://doi.org/10.1007/s00508-012-0310-2

Springer Medizin Österreich

Summary

Objectives

Methods

Results

Conclusions

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