Thromb Haemost 2011; 105(02): 379-381
DOI: 10.1160/TH10-09-0619
Letters to the Editor
Schattauer GmbH

Adjacent substitutions (γ352Gly→Cys and 353Thr→Pro) in fibrinogen Ilam cause diminished γ chain expression

Stephen O. Brennan
1   Molecular Pathology Laboratory, Pathology Department, University of Otago, Christchurch, New Zealand
2   Canterbury Health Laboratories, Christchurch, New Zealand
,
Jocelyn Oliver
2   Canterbury Health Laboratories, Christchurch, New Zealand
,
Ryan L. Davis
1   Molecular Pathology Laboratory, Pathology Department, University of Otago, Christchurch, New Zealand
› Author Affiliations
Further Information

Publication History

Received: 27 September 2010

Accepted after minor revision: 27 October 2010

Publication Date:
25 November 2017 (online)

 

 
  • References

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  • 9 Brennan SO, Davis RL. Substitution (γ335Trp→Arg) in fibrinogen Fremantle causes diminished γ chain expression and increased sialic acid content. Thromb Haemost 2010; 104: 1274-1276.
  • 10 Dib N, Quelin F, Ternisien C. et al. Fibrinogen Angers with a new deletion (γ GVYYQ 346–350) causes hypofibrinogenemia with hepatic storage. J Thromb Haemost 2007; 5: 1999-2005.
  • 11 Kruse KB, Dear A, Kaltenbrun ER. et al. Mutant fibrinogen cleared from the ER via ERAD and auto-phagy: an explanation for liver disease. Am J Pathol 2006; 168: 1299-1308.