On the Role of 17-OH-19-epi-Cathenamine in the Biosynthesis of Heteroyohimbine Alkaloids

J. Stöckigt; M. Rueffer; Ch. Kan-Fan; H.-P. Husson

doi:10.1055/s-2008-1074905

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml

Share / Bookmark

Facebook X Linkedin Weibo

Download PDF

Planta Med 1980; 39(5): 73-76
DOI: 10.1055/s-2008-1074905

Research Articles

On the Role of 17-OH-19-epi-Cathenamine in the Biosynthesis of Heteroyohimbine Alkaloids

J. Stöckigt¹ , M. Rueffer¹ , Ch. Kan-Fan² , H.-P. Husson²

¹Lehrstuhl für Pflanzenphysiologie, Ruhr-Universität Bochum, Bochum, W.-Germany
²Institut de Chimie des Substances Naturelles, C.N.R.S. F-91190 Gif-sur-Yvette, France

Further Information

Publication History

Publication Date:
29 April 2008 (online)

PDF Download Permissions and Reprints

Abstract

17-OH-19-epi-Cathenamine (10) -which is known to be a precursor of 19-epi-ajmalicine (7) under biomimetic conditions - is not involved in the biosynthetic formation of 7. 10 does, however, undergo enzymatic reduction to 17-OH-19-epi-ajmalicine (11) in the presence of cell-free extracts of Catharanthus roseus cell suspension cultures and NADPH.

Key Word Index

Catharanthus roseus - Apocynaceae - Cell Suspension Cultures - Enzymatic Formations - Heteroyohimbine Type Alkaloids - Role of 17-OH-19-epi-Cathenamine.

>