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Planta Med 1984; 50(4): 285-288
DOI: 10.1055/s-2007-969710
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Alkaloids from Roots of Strempeliopsis strempelioides - Structures of Strempeliopine and Strempeliopidine[1]

A. Laguna2 , L. Novotný3 , L. Dolejš3 , M. Buděšínský3
  • 2Phytochemistry Laboratory, National Centre of Scientific Research, Havana, Cuba
  • 3Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague, Czechoslovakia
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Publication History

1983

1984

Publication Date:
26 February 2007 (online)

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Abstract

From the roots of Strempeliopsis strempelioides K. Schum. (Apocynaceae), the following alkaloids were isolated: (+)-pleiocarpamine, (-)-aspidospermine, (+)-eburnamonine, (+)-tubotaiwine, (+)-haplocidine, (-)-vallesamidine, (+)-tubotaiwine N-oxide, (-)-strempeliopine (1a) and a bisindolic base (+)-strempeliopidine (2). Another bisindole alkaloid of composition C38H46N4 was isolated in minute quantity. The structures were established on the basis of spectral and chemical evidence.

1 Part XCVII in the series Plant Substances; Part XCVI: see ref. (1). This work represents a part of the Thesis of A. Laguna, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences 1980. Presented at the “29. Vortragstagung der Gesellschaft für Arzneipflanzenforschung” in Marburg/Lahn, 9.-13. June 1981, see Planta Medica 42, 135 (1981).

1 Part XCVII in the series Plant Substances; Part XCVI: see ref. (1). This work represents a part of the Thesis of A. Laguna, Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences 1980. Presented at the “29. Vortragstagung der Gesellschaft für Arzneipflanzenforschung” in Marburg/Lahn, 9.-13. June 1981, see Planta Medica 42, 135 (1981).

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