Fortschr Neurol Psychiatr 2006; 74(11): 634-642
DOI: 10.1055/s-2005-919079
Originalarbeit
© Georg Thieme Verlag Stuttgart · New York

Substanz-bezogene Störungen: Auf dem Weg zu ICD-11 und DSM-V

Substance Induced Disorders: Moving Towards DSM-V and ICD-11L.  G.  Schmidt1
  • 1Psychiatrische Klinik und Poliklinik, Johannes Gutenberg-Universität Mainz
Further Information

Publication History

Publication Date:
02 January 2006 (online)

Zusammenfassung

Perspektiven zur Entwicklung „Substanzbezogener Störungen” für DSM-V werden gemäß einer Expertenkonferenz aufgezeigt, die von der amerikanischen Psychiatergesellschaft (APA) unter dem Vorsitz von M.A. Schuckit und J.B. Saunders organisiert wurde. Internationale Experten hatten die Erwartung, dass eine weitreichende Kompatibilität mit der ICD-11 der WHO erreicht werden könnte. Es wurde davon ausgegangen, dass es bei den Substanz-bezogenen Störungen auch in DSM-V weiterhin ein Abhängigkeitssyndrom, eine klinisch bedeutsame Nicht-Abhängigkeits-Kategorie und eine unterschwellige (Risiko-)Kondition geben wird. Es werden wohl kategoriale und dimensionale Kriterien, letztere als quantitative Ausformulierungen der kategorialen Merkmale aufgenommen werden. Neben generellen wurden auch Substanz-spezifische Abhängigkeits-Kriterien diskutiert. Forschungsbedarf wurde für das Problem der Abgrenzung Substanz-induzierter von (Substanz-)unabhängigen psychischen Störungen konstatiert, um die Komorbidität der Patienten mit Substanz-bezogenen Störungen angemessen zu codieren. Es ist offen, ob das Ziel erreicht werden kann, biologische Kriterien zur Verminderung der Beurteilungsvarianz bei Substanz-bezogenen Störungen in DSM-V aufzunehmen.

Abstract

The development of substance abuse disorders (SUD) for DSM-V is put into perspective according to an expert meeting organized by APA and chaired by M.A. Schuckit and J.B. Saunders. Substantial compatibility with ICD-11 of WHO was expected to be achieved. A dependence syndrome, a non-dependence category as well as a subthreshold condition is supposed to be included in the SUD section in DSM-V. Categorical criteria will possibly be supplemented by dimensions conceptualized as quantitative formulations of criteria content. General and substance-specific criteria may be included for dependence. The comorbidity problem requires more research to separate substance-induced from substance-independent mental disorders in patients with SUDs. It was an open discussion, whether the aim to include biological criteria for better defining of SUDs will be achieved in DSM-V.

Literatur

  • 1 APA: Diagnostische Kriterien des Diagnostischen und Statistischen Manuals Psychischer Störungen DSM IV. Göttingen: Hogrefe 1998
  • 2 Weltgesundheitsorganisation .Internationale Klassifikation psychischer Störungen. Klinisch-diagnostische Leitlinien. 4. Auflage. Bern: Huber 2000
  • 3 Kupfer D J, First M B, Regier D A. A research agenda for DSM-V. Washington D.C.: American Psychiatric Publishing Inc 2002
  • 4 Robins L N. Using survey results to improve the validity of the standard psychiatric nomenclature.  Arch Gen Psychiat. 2004;  61 188-1194
  • 5 Self D. Drug dependence and addiction: neural substrates.  Am J Psychiat. 2004;  161 223
  • 6 Edwards G, Gross M. Alcohol dependence: provisional description of a clinical syndrome.  Br Med J. 1976;  1 1058-1061
  • 7 Feingold A, Rounsaville B. Construct validity of the dependence syndrome as measured by DSM-IV for different psychoactive substances.  Addiction. 1995;  90 1661-1669
  • 8 Lessov C N, Martin N G, Statham D J, Todorov A A, Slutske W S, Bucholz K K, Heath A C, Madden P AF. Defining nicotine dependence for genetic research: evidence from Australian twins.  Psychol Med. 2004;  34 865-879
  • 9 Wu L T, Pilowsky D J, Schlenger W E. Inhalant abuse and dependence among adolescents in the United States.  J Am Acad Child Adolesc Psychiat. 2004;  43 1206-1214
  • 10 Tyrer P. Risks of dependence on benzodiazepine drugs: the importance of patient selection.  Br Med J. 1989;  102 104
  • 11 Copeland J, Peters R, Dillon P. Anabolic-androgenic steroid use disorders among a sample of Australian competitive and recreational users.  Drug Alc Depend. 2000;  60 91-96
  • 12 Lejoyeux M, McLoughlin M, Ades J. Epidemiology of behavioural dependence: literature review and results of original studies.  Eur Psychiat. 2000;  15 129-134
  • 13 Edwards G, Arif A, Hadgson R. Nomenclature and classification of drug- and alcohol-related problems: a WHO Memorandum.  Bull World Health Organ. 1981;  59 225-242
  • 14 World Health Organisation (WHO) .Regional Office for Europe: Alcohol and health - implications for Public Health Policy. Norway: Report of a WHO Working Group 1995
  • 15 British Medical Association (BMA) .Alcohol. Guidelines on sensible drinking. London: British Medical Association 1995
  • 16 Sartorius N, Kaelber C T, Cooper J E, Roper N T, Rae D S, Gulbinat W, Ustun T B, Regier D A. Progress towards achieving a common language in Psychiatry. Results from the field trial of the clinical guidelines accompanying the WHO classification of mental and behavioral disorders in ICD-10.  Arch Gen Psychiat. 1993;  50 115-124
  • 17 Edwards G. The alcohol dependence syndrome: a concept as stimulus to enquiry.  Br J Addiction. 1986;  81 171-183
  • 18 Schuckit M A, Hesselbrock V, Tipp J, Anthenelli R, Bucholz K, Radziminski S. A comparison of DSM-III-R, DSM-IV and ICD-10 substance use disorders diagnoses in 1992 men and women subjects in the COGA study.  Addiction. 1994;  89 1629-1638
  • 19 Ustun B, Compton W, Mager D, Babor T, Baiyewu O, Chatterji S, Cottler L, Gogus A, Mavreas V, Peters L, Pull C, Saunders J, Smeets R, Stipec M R, Vrasti R, Hasin D, Room R, Brink W van den, Regier D, Blaine J, Grant B F, Sartorius N. WHO study on the reliability and validity of the alcohol and drug use disorder instruments: overview of methods and results.  Drug Alc Depend. 1997;  47 161-169
  • 20 Pull C B, Saunders J, Mavreas V. et al . Concordance between ICD-10 alcohol and drug use disorder criteria and diagnoses as measured by the AUDADIS-ADR, CIDI and SCAN: results of a cross national study.  Drug Alc Depend. 1997;  47 207-216
  • 21 Hasin D. Classification of alcohol use disorders.  Alcohol Res & Health. 2003;  27 5-17
  • 22 Schmidt L G, Dufeu P, Rommelspacher H. Diagnostik der Alkoholabhängigkeit.  Nervenarzt. 1993;  64 36-44
  • 23 Grant B F. ICD-10 and proposed DSM-IV harmful use of alcohol/alcohol abuse and dependence, United States 1988: a nosological comparison.  Alc Clin Exp Res. 1993;  17 1093-1101
  • 24 Hasin D S, Grant B. Nosological comparisons of DSM-III-R and DSM-IV alcohol abuse and dependence in a clinical facility: comparison with the 1988 national health Interview survey results.  Alc Clin Exp Res. 1994;  18 272-279
  • 25 Martin C S, Kaszynski N A, Maisto S A, Bukstein O M, Moss H B. Patterns of DSM-IV alcohol abuse and dependence symptoms in adolescent drinkers.  J Stud Alc. 1995;  56 672-680
  • 26 Nelson C B, Wittchen H U. DSM-IV alcohol disorders in a general population sample of adolescents and young adults.  Addiction. 1998;  93 1065-1067
  • 27 Heath A C, Bucholz K K, Slutske W S. et al . The assessment of alcoholism in surveys of the general community: what are we measuring? Some insights from the Australian twin panel interview survey.  International Review of Psychiatry. 1994;  6 295-307
  • 28 Fulkerson J A, Harrison P A, Beebe T J. DSM-IV substance abuse and dependence: are there really two dimensions of substance disorders in adolescents?.  Addiction. 1995;  94 495-506
  • 29 Nelson C B, Rehm J, Ustun T B, Grant B, Chatterji S. Factor structure for DSM-IV substance disorders criteria endorsed by alcohol, cannabis, cocaine and opiate users: results from the WHO reliability and validity study.  Addiction. 1999;  94 843-855
  • 30 Teesson M, Lynskey M, Manor B, Baillie A. The structure of cannabis dependence in the community.  Drug Alc Depend. 2002;  68 266-262
  • 31 Harford T C, Muthen B. The dimensionality of alcohol abuse and dependence: a multivariate analysis of DSM-IV symptom items in the National Longitudinal Survey of Youth.  J Stud Alc. 2001;  62 150-157
  • 32 Schuckit M A, Smith T L, Danko G P, Bucholz K K, Reich T, Bierut L. Five-year clinical course associated with DSM-IV alcohol abuse or dependence in a large group of men and women.  Am J Psychiat. 2001;  158 1084-1090
  • 33 Schuckit M A, Dank G P, Smith T L, Hesselbrock V, Kramer J, Bucholz K. A 5-year prospective evaluation of the DSM-IV alcohol dependence with and without a physiological component.  Alc Clin ExpRes. 2003;  27 818-825
  • 34 DeBellis M D. Developmental traumatology: a contributory mechanism for alcohol and substance use disorders.  Psychoneuroendocrinol. 2002;  27 155-170
  • 35 Hasin D, Rossem R van, McCloud S, Endicott J. Alcohol dependence and abuse diagnoses: validity in community sample heavy drinkers.  Alc Clin Exp Res. 1997;  21 213-219
  • 36 Hoffmann N G, Hoffmann T D. Construct validity for alcohol dependence as indicated by the SUDDS-IV.  Substance Use and Misuse. 2003;  38 293-306
  • 37 Hasin D, Paykin A. Alcohol dependence and abuse diagnoses: concurrent validity in a national representative sample.  Alc Clin Exp Res. 1999;  23 144-150
  • 38 Hasin D S, Grant B F. Major depression in 6,050 former drinkers: association with past alcohol dependence.  Arch Gen Psychiat. 2002;  59 794-800
  • 39 Schuckit M A, Smith T L, Daeppen J B, Eng M, Li T K, Hesselbrock V M, Nurnberger Jr J I, Bucholz K K. Clinical relevance of the distinction between alcohol dependence with and without a physiological component.  Am J Psychiat. 1998;  155 733-740
  • 40 Hasin D, Paykin A, Meydan J, Grant B F. Withdrawal and tolerance in DSM-IV alcohol dependence.  J Stud Alc. 2000;  63 431-438
  • 41 Hasin D, Grant B F, Endicott J. The natural history of alcohol abuse: implications for the definitions of alcohol use disorders.  Am J Psychiat. 1990;  147 1537-1541
  • 42 Langenbucher J W, Chung T. Onset and staging of DSM-IV alcohol dependence using mean age and survivalized methods.  J Abn Psychol. 1995;  104 346-354
  • 43 Grant B F, Stinson F S, Harford T C. Age at onset of alcohol use, and DSM-IV alcohol and substance abuse and dependence: a 12-year follow up.  J Subst Abuse. 2001;  13 493-504
  • 44 Ridenour T A, Cottler L B, Compton W M, Spitznagel W M, Cunningham-Williams R M. Is there a progression from abuse disorders to dependence disorders?.  Addiction. 2003;  98 635-644
  • 45 Schuckit M A, Smith T L, Danko G P, Kramer J, Godinez J, Bucholz K K, Nurnberger J I, Hesselbrock V. Prospective evaluation of the four DSM-IV criteria for alcohol abuse in a large population.  Am J Psychiat. 2005;  162 350-360
  • 46 Eng M Y, Schuckit M S, Smith T L. A five-year prospective study of diagnostic orphans for alcohol use disorders.  J Stud. Alc2003;  64 227-234
  • 47 Degenhardt L, Lynskey M, Coffey C, Patton G. “Diagnostic orphans” among young adult cannabis users: persons who report dependence symptoms but do not meet diagnostic criteria.  Drug Alc Depend. 2002;  67 205-212
  • 48 Rounsaville B J, Bryant K, Babor T F. et al . Cross-system agreement for substance use disorders: DSM-IIIR, DSM-IV and ICD-10.  Addiction. 1993;  88 337-348
  • 49 Bucholz K K, Cadoret R, Cloninger C R, Dinwiddie S H, Hesselbrock V M, Nurnberger Jr J I, Reich T, Schmidt I, Schuckit M A. A new, semi-structured psychiatric inerview for use in genetic linkage studies: a report on the reliability of the SSAGA.  J Stud Alc. 1994;  55 149-158
  • 50 Cottler L B, Grant B F, Blaine J. et al . Concordance of DSM-IV alcohol and drug use disorder criteria and diagnoses as measured by AUDADIS-ADR, CIDI and SCAN.  Drug Alc Depend. 1997;  47 195-205
  • 51 Chatterji S, Saunders J, Vrasti R. et al . Reliability of the alcohol and drug modules of the Alcohol Use Disorders and Associated Disabilities Interview Schedule-Alcohol/Drug Revised (AUDADIS-ADR): an international comparison.  Drug Alc Depend. 1997;  47 171-185
  • 52 Rounsaville B J. Experience with ICD-10/DSM-IV substance use disorders.  Psychopathology. 2002;  35 82-88
  • 53 Kramer H C, Noda A, O'Hara R. Categorical vs. dimensional approaches to diagnosis: methodological challenger.  J Psychiat Res. 2004;  38 17-25
  • 54 Os J van, Gilvary C, Bale R, Horn E van, Tattan T, White I, Murray R. A comparison of the utility of dimensional and categorical representations of psychosis. UK700 Group.  Psychol Med. 1999;  29 595-606
  • 55 Peralta V, Cuesta M J. Clinical models of schizophrenia: a critical approach to competing conceptions.  Psychopathology. 2000;  33 252-258
  • 56 Peralta V, Cuesta M J, Giraldo C, Cardenas A, Gonzales F. Classifying psychotic disorders: issues regarding categorical vs. dimensional approaches and time frame to assess symptoms.  Eur Arch Psychiat Clin Neurosci. 2002;  252 12-18
  • 57 Wanberg K W, Horn J L, Foster F M. A differential assessment model for alcoholism. The scales of the Alcohol Use Inventory.  J Stud Alc. 1977;  38 512-543
  • 58 Tarter R E, Moss H B, Arria A, Mezzich A C, Vanyukov M M. The psychiatric diagnosis of alcoholism: critique and proposed reformation.  Alc Clin Exp Res. 1992;  16 106-116
  • 59 Mayfield D, McLeod G, Hall P. The CAGE questionnaire: validation of a new alcoholism screening instrument.  Am J Psychiat. 1974;  131 1121-1123
  • 60 Saunders J B, Aasland O G, Babor T F, de la Fuente J R, Grant M. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption. II.  Addiction. 1993;  88 791-804
  • 61 Skinner H A, Allen B A. Alcohol dependence syndrome: measurement and validation.  J Abn Psychol. 1982;  91 199-209
  • 62 Mc Lellan A T, Luborsky L, Woody G E. An improved diagnostic evaluation instrument for substance abuse patients: the Addiction Severity Index.  J Nerv Ment Dis. 1980;  168 26-33
  • 63 Cottler L B, Keating S K. Operationalization of drug and alcohol dependence criteria by means of a structured interview.  Recent Develop Alc. 1990;  8 69-83
  • 64 Spitzer R L, Williams J, Kroenke K. Research Quick Guide to Patient Health Questionnaire (PHQ) and Brief PHQ. New York: New York State Psychiatric Institute 1999
  • 65 Regier D A, Kaelber C T, Rae D S, Farmer M E, Knauper B, Kessler R C, Norquist G S. Limitations of diagnostic criteria and assessment instruments for mental disorders. Implications for research and policy.  Arch Gen Psychiatry. 1998;  55 109-115
  • 66 Regier D A, Farmer M E, Rae D S, Locke B Z, Keith S J, Judd L L, Goodwin F K. Comorbidity of mental disorders with alcohol and other drugs of abuse. Results from the Epidemiologic Catchment Area (ECA) Study.  JAMA. 1990;  264 2511-2518
  • 67 Kessler R C, Crum R M, Warner L A, Nelson C B, Schulenberg J, Anthony J C. Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey.  Arch Gen Psychiat. 1997;  54 313-321
  • 68 Shiffman S, Waters A J, Pomerlau C S, Bolt D M, Brigham J, Swan G E. A multidimensional measure of nicotine dependence.  Nicotine and Tobacco Research. 2003;  5 655-664
  • 69 Budney A J, Hughes J R, Moore B A, Vandrey R. Review of the validity and significance of cannabis withdrawal syndrome.  Am J Psychiatry. 2004;  161 1967-1977
  • 70 Maser J D, Patterson P. Spectrum and nosology: implications for DSM-V.  Psychiatric Clinics of North America. 2002;  25 855-885
  • 71 O'Brian C P, Charney D S. Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action.  Biol Psychiat. 2004;  56 703-713
  • 72 Grant B F, Stinson F S, Dawson D A, Chou S P, Dufour M C, Compton W, Pickering R P, Kaplan K. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the national Epidemiologic Survey on Alcohol and Related Conditions.  Arch Gen Psychiat. 2004;  61 807-816
  • 73 Schuckit M A, Tipp T E, Bucholz K K, Nurnberger Jr J I, Hesselbrock V M, Crowe R R, Kramer J. The life-time rates of three major mood disorders and four major anxiety disorders in alcoholics and controls.  Addiction. 1997;  92 1289-1304
  • 74 Hambrecht M, Häfner H. Substance abuse and the onset of schizophrenia.  Biol Psychiat. 1996;  40 1155-1163
  • 75 Zammit S, Allebeck P, Andreasson S, Lundberg I, Lewis G. Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study.  Br Med J. 2002;  325 1199-1201
  • 76 Zammit S, Allebeck P, Dalman C, Lundberg I, Hemmingsson T, Lewis G. Investigating the association between cigarette smoking and schizophrenia in a cohort study.  Am J Psychiat. 2003;  160 2216-2221
  • 77 Bolanos C A, Barrot M, Berton O, Wallace-Black D, Nestler E J. Methylphenidate treatment during pre- and periadolescence alters behavioural respsonses to emotional stimuli at adulthood.  Biol Psychiat. 2003;  54 1317-1329
  • 78 Volkow N D. The reality of comorbidity: depression and drug abuse.  Biol Psychiat. 2004;  56 714-717
  • 79 Caton C LM, Drake R E, Hasin H S, Dominguez B, Shrout P E, Samet S, Schanzer W B. Differences between early-phase primary psychotic disorders with concurrent substance use and substance-induced psychoses.  Arch Gen Psychiat. 2005;  62 137-145
  • 80 Hasin D S, Trautman K D, Miele G M, Sarnet S, Smith M, Endicott J. Psychiatric research interview for substance and mental disorders (PRISM): reliability for substance abusers.  Am J Psychiat. 1996;  153 1195-1201
  • 81 Grant B F, Harford T C, Dawson D A, Chou P S, Pickering R P. The Alcohol Use Disorder and Associated Disabilities Interview schedule (AUDADIS): reliability of alcohol and drug modules in a general population sample.  Drug Alcohol Depend. 1995;  39 37-44
  • 82 Bucholz K K, Cadoret R, Cloninger C R, Dinwiddie S H, Hesselbrock V M, Nurnberger Jr J I, Reich T, Schmidt I, Schuckit M A. A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.  J Stud Alcohol. 1994;  55 149-158
  • 83 Nunes E V, Levin F R. Treatment of depression in patients with alcohol or other drug dependence: a meta-analysis.  JAMA. 2004;  291 1887-1896
  • 84 Babor T F, Hoffman M, Del Boca F K, Hesselbrock V, Meyer R E, Dolinsky Z S, Rounsaville B. Types of alcoholics, I: evidence for an empirically derived typology based on indicators of vulnerability and severity.  Arch Gen Psychiat. 1992;  49 599-608
  • 85 Windle M, Scheidt D M. Alcoholic subtypes: are two sufficient?.  Addiction. 2004;  99 1508-1519
  • 86 Krueger R F. The structure of common mental disorders.  Arch Gen Psychiat. 1999;  56 921-926
  • 87 Li T K, Hewitt B G, Grant B F. Alcohol use disorders and mood disorders: a National Institute on Alcohol Abuse and Alcoholism perspective.  Biol Psychiat. 2004;  56 718-720
  • 88 Volkow N D, Wang G J, Fowler J S, Logan J, Hitzemann R, Ding Y S, Pappas N, Shea C, Piscani K. Decreases in dopamine receptors but not in dopamine transporters in alcoholics.  Alcohol Clin Exp Res. 1996;  20 1594-1598
  • 89 Heinz A, Siessmeier T, Wrase J, Hermann D, Klein S, Grusser S M, Flor H, Braus D F, Buchholz H G, Grunder G, Schreckenberger M, Smolka M N, Rosch F, Mann K, Bartenstein P. Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving.  Am J Psychiatry. 2004;  161 1783-1789
  • 90 Nestler A J, Agjanian G K. Molecular and cellular basis of addiction.  Science. 1997;  278 58-63
  • 91 Rangaswamy M, Porjesz B, Chorlian D B, Wang K, Jones K A, Bauer L O, Rohrbaugh J, O'Connor S J, Kuperman S, Reich T, Begleiter H. Beta power in the EEG of alcoholics.  Biol Psychiatry. 2002;  52 831-842
  • 92 Edenberg H J, Dick D M, Xuei X, Tian H, Almasy L, Bauer L O, Crowe R R, Goate A, Hesselbrock V, Jones K, Kwon J, Li T K, Nurnberger Jr J I, O"Connor S J, Reich T, Rice J, Schuckit M A, Porjesz B, Foroud T, Begleiter H. Variations in GABA2, encoding the alpha 2 subunit of the GABA(A) receptor are associated with alcohol dependence and with brain oscillations.  Am J Hum Genet. 2004;  74 705-714
  • 93 Higuchi S, Matsushita S, Imazeki H, Kinoshita T, Takagi S, Kono H. Aldehyde dehydrogenase genotypes in Japanese alcoholics.  Lancet. 1994;  343 741-742
  • 94 Petry N M. Substance abuse, pathological gambling, and impulsiveness.  Drug Alcohol Depend. 2001;  63 29-38
  • 95 Reuter J, Rädler T, Rose M, Hand I, Glaser J, Buchel C. Pathological gambling is linked to reduced activation of the mesolimbic reward system.  Nat Neurosci. 2005;  8 147-148
  • 96 Kessler R C, Merikangas K R, Berglund P, Eaton W W, Koretz D S, Walters E E. Mild disorders should not be eliminated from the DSM-V.  Arch Gen Psychiat. 2003;  60 1117-1122

Prof. Dr. med. Lutz G. Schmidt

Psychiatrische Klinik und Poliklinik, Johannes Gutenberg-Universität

Untere Zahlbacher Str. 8

55131 Mainz

Email: schmidt@psychiatrie.klinik.uni-mainz.de

    >