Thromb Haemost 1979; 42(02): 803-804
DOI: 10.1055/s-0038-1666920
Letter to the Editor
Schattauer GmbH Stuttgart

Prostacyclin Activity is Diminished in Different Types of Morphologically Controlled Human Atherosclerotic Lesions

H Sinzinger
1)   Atherosclerosis Research Group at the Department of Medical Physiology, Schwarzspanierstraße 17, A-1090 Vienna, Austria
,
K Silberbauer
2)   2nd Department of Internal Medicine, Schwarzspanierstraße 17, A-1090 Vienna, Austria
,
W Feigl
3)   Department of Pathology, Schwarzspanierstraße 17, A-1090 Vienna, Austria
,
O Wagner
4)   1st Department of Surgery, University of Vienna, Schwarzspanierstraße 17, A-1090 Vienna, Austria
,
M Winter
4)   1st Department of Surgery, University of Vienna, Schwarzspanierstraße 17, A-1090 Vienna, Austria
,
W Auerswald
1)   Atherosclerosis Research Group at the Department of Medical Physiology, Schwarzspanierstraße 17, A-1090 Vienna, Austria
› Author Affiliations
Further Information

Publication History

Publication Date:
23 August 2018 (online)

 
  • References

  • 1 D’Angelo V, Villa S, Mysliwiec M, Donati MB, Degatenao G. 1978; Defective fibrinolytic and prostacyclin-like activity in human atheromatous plaques. Thrombosis and Haemostasis 39: 535
  • 2 Donati MB. 1978 personal communication
  • 3 Gryglewski R, Bunting S, Moncada S, Flower RJ, Vane JR. 1976; Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. Prostaglandins 12: 685
  • 4 Gryglewski RJ, Dembinska-Kiec A, Zmuda A, Gryglewska T. 1978; Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits. Atherosclerosis 31: 385
  • 5 Moncada S, Gryglewski RJ, Bunting S, Vane JR. 1976; A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides a substance (prostaglandin x) which prevents platelet aggregation. Prostaglandins 12: 715
  • 6 Moncada S, Higgs EA, Vane JR. 1977; Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation. Lancet 1: 18
  • 7 Silberbauer K, Sinzinger H, Winter M. 1978; a Prostacyclin production by vascular smooth muscle cells. Lancet 1: 1356
  • 8 Sinzinger H, Silberbauer K, Winter M. 1978; b Prostacyclin - Hemmwirkung auf die Thrombozytenanlagerung an die Gefäßwand in vivo. VASA 7: 350
  • 9 Sinzinger H, Silberbauer K, Wagner O, Winter M, Auerswald W. 1978; Prostacyclin - preliminary results with vascular tissue of various species and its importance for atherosclerotic involvement. Atherogenese 3: 123
  • 10 Sinzinger H, Silberbauer K, Winter M, Wurm E. 1979 a Relation between fibrinolytic activity and prostacyclin generation of atherosclerotic artery and dacron prosthetic graft. Experientia. (in press)
  • 11 Sinzinger H, Clopath P, Silberbauer K, Winter M. 1979. b Effects of experimental atherosclerosis on prostacyclin (PGI2) generation in arteries of miniature swine. Artery. (in press)
  • 12 Sinzinger H, Silberbauer K, Winter M. 1979 c Vaskulärer Faktor als Thromboregulations- mechanismus. Verh. Dtsch. Ges. Angiol. (in press)