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Thromb Haemost 1986; 55(02): 293
DOI: 10.1055/s-0038-1661540
Letter to the Editor
Schattauer GmbH Stuttgart

Effect of Injection of C1 Inactivator on the Platelet Count and Blood Coagulation in Rabbits Infused with Endotoxin

D C Triantaphyllopoulos
American Red Cross Biomedical Research andDevelopment Laboratories Bethesda, Maryland, USA and Department of Physiology and Biophysics Georgetown University Medical School Washington,D.C., USA
,
M S Cho
American Red Cross Biomedical Research andDevelopment Laboratories Bethesda, Maryland, USA and Department of Physiology and Biophysics Georgetown University Medical School Washington,D.C., USA
› Author Affiliations
Further Information

Publication History

Received 05 August 1985

Accepted 16 December 1985

Publication Date:
18 July 2018 (online)

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  • References

  • 1 Osterud B, Bjorklid E. Human factor VII associated with endotoxin stimulated monocytes in whole blood. Biochem Biophys Res Commun 1982; 108: 620-626
    CrossrefPubMedGoogle Scholar
  • 2 Colucci M, Balconi G, Lorenzet R, Pietra A, Donati A MB, Semeraro N. Evidence that cultured human endothelial cells (EC) generate tissue factor in response to endotoxin. Thromb Haemostas 1983; 50: 253 (Abstr)
    PubMedGoogle Scholar
  • 3 Brox JH, Osterud B, Bjorklid E, Fenton JW. Production and availability of thromboplastin in endothelial cells: the effects of thrombin, endotoxin and platelets. Brit J Haematol 1984; 57: 239-246
    CrossrefPubMedGoogle Scholar
  • 4 Morrison DC, Cochrane CG. Direct evidence for Hageman factor (factor XII) activation by bacterial lipopolysaccharides (endotoxins). J Exp Med 1974; 140: 797-811
    CrossrefPubMedGoogle Scholar
  • 5 Nagayama M, Zucker MB, Beller F. Effects of a variety of endotoxins on human and rabbit platelet function. Thrombos Diathes Haemorrh 1971; 26: 467-473
    PubMedGoogle Scholar
  • 6 Kane MA, May JE, Frank MM. Interactions of the classical and alternate complement pathway with endotoxin lipopolysaccharide. Effect on platelets and blood coagulation. J Clin Investig 1973; 52: 370-376
    CrossrefPubMedGoogle Scholar
  • 7 Triantaphyllopoulos DC. Effects of human antithrombin III on mortality and blood coagulation induced in rabbits by endotoxin. Thromb Haemostas 1984; 51: 232-235
    PubMedGoogle Scholar
  • 8 Everett MM, Emerson TE. Antithrombin III (AT III) increases survival tim e and diseases mortality during endotoxin shock in the rat. Cicul Shock 1984 13. Abst 29
    PubMedGoogle Scholar
  • 9 Pixley RA, Schapira M, Colman RW. The regulation of human factor Xlla by plasma proteinase inhibitors. J Biol Chem 1985; 260: 1723-1729
    PubMedGoogle Scholar
  • 10 Sim RB, Reboul A, Arlaud GJ, Villiers CL, Colomb MG. Interaction of 125I-labelled complement subcomponents Clr and Cls with protease inhibitors in plasma. FEBS Lett 1979; 97: 111-115
    CrossrefPubMedGoogle Scholar
  • 11 Ziccardi RJ. Activation of the early components of the classical component pathway under physiologic conditions. J Immunol 1981; 126: 1769-1773
    PubMedGoogle Scholar
  • 12 Gallimore MJ, Amundsen E, Larsbraaten M, Lyngaas K, Fareid E. Studies on plasma inhibitors of plasma kallikrein using chromogenic substrate assays. Thromb Res 1979; 16: 695-703
    CrossrefPubMedGoogle Scholar
  • 13 Forbes CD, Pensky J, Ratnoff OD. Inhibition of activated Hageman factor and activated plasma thromboplastin antecedent by purified Cl inactivator. J Lab Clin Med 1970; 76: 809-815
    PubMedGoogle Scholar
  • 14 Wickerhauser M, Hao Y L, Mercer J. Method for large scale preparation of Cl inhibitor concentrate for clinical studies (Abstr). Joint Congress of the International Societies of Hematology and Blood Transfusion Paris: 1978
    Google Scholar
  • 15 Lennick M, Brew SA, Ingham KC. Changes in protein configuration and stability accompanying complex formation between Cl inhibitor and Cls. Biochem 1985; 24: 2561-2568
    CrossrefPubMedGoogle Scholar