J Reconstr Microsurg 2016; 32(02): 114-120
DOI: 10.1055/s-0035-1563397
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Microvascular Anastomoses Using End-to-End versus End-to-Side Technique in Lower Extremity Free Tissue Transfer

Eugenia H. Cho
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
,
Ryan M. Garcia
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
,
Jared Blau
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
,
Howard Levinson
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
,
Detlev Erdmann
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
,
L. Scott Levin
2   Department of Orthopaedic Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania
,
Scott T. Hollenbeck
1   Division of Plastic and Reconstructive Surgery, Duke University Health System, Durham, North Carolina
› Author Affiliations
Further Information

Publication History

07 April 2015

06 July 2015

Publication Date:
31 August 2015 (online)

Abstract

Background The decision to perform an end-to-end (ETE) or end-to-side (ETS) arterial anastomosis in lower extremity free tissue transfer has not been thoroughly evaluated in a large multisurgeon setting. The authors compared the reconstructive outcomes of lower extremity free flaps with ETE and ETS arterial anastomoses.

Methods The authors retrospectively reviewed their 17-year institutional experience with lower extremity free flaps to determine whether ETE or ETS arterial anastomoses were associated with foot ischemic complications and flap failure.

Results From 1996 to 2013, 398 patients underwent 413 lower extremity free flaps with ETE (66%) or ETS (34%) arterial anastomoses. The incidence of postoperative foot ischemia was 2% (n = 8). The flap failure rate was 11% (n = 45). The ETS technique was preferred in patients with fewer intact vessels to the foot (32% ETS for three-vessel runoff, 36% ETS for two-vessel runoff, and 50% ETS for single-vessel runoff) and when an intact recipient vessel was selected for anastomosis (60% ETS for intact vessel vs. 25% ETS for distally occluded vessel). No differences were observed in the foot ischemia (p = 0.45) and flap failure rates (p = 0.59) for ETE versus ETS arterial anastomoses. In subset analyses, the incidence of foot ischemia did not differ for either technique in the context of impaired vascular runoff or recipient vessel selection.

Conclusion No advantage was noted for ETE or ETS arterial anastomoses based on reconstructive outcomes. The choice of anastomotic technique in lower extremity free tissue transfer should be based on patient factors and the clinical circumstances encountered.

 
  • References

  • 1 Park S, Han SH, Lee TJ. Algorithm for recipient vessel selection in free tissue transfer to the lower extremity. Plast Reconstr Surg 1999; 103 (7) 1937-1948
  • 2 Attinger C, Cooper P, Blume P, Bulan E. The safest surgical incisions and amputations applying the angiosome principles and using the Doppler to assess the arterial-arterial connections of the foot and ankle. Foot Ankle Clin 2001; 6 (4) 745-799
  • 3 Attinger CE, Evans KK, Bulan E, Blume P, Cooper P. Angiosomes of the foot and ankle and clinical implications for limb salvage: reconstruction, incisions, and revascularization. Plast Reconstr Surg 2006; 117 (7, Suppl): 261S-293S
  • 4 Cho EH, Garcia RM, Pien I , et al. Vascular considerations in foot and ankle free tissue transfer: analysis of 231 free flaps. Microsurgery 2015; . doi: 10.1002/micr.22406
  • 5 Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plast Reconstr Surg 1986; 78 (3) 285-292
  • 6 Heller L, Levin LS. Lower extremity microsurgical reconstruction. Plast Reconstr Surg 2001; 108 (4) 1029-1041 , quiz 1042
  • 7 Albertengo JB, Rodriguez A, Buncke HJ, Hall EJ. A comparative study of flap survival rates in end-to-end and end-to-side microvascular anastomosis. Plast Reconstr Surg 1981; 67 (2) 194-199
  • 8 Godina M. Preferential use of end-to-side arterial anastomoses in free flap transfers. Plast Reconstr Surg 1979; 64 (5) 673-682
  • 9 Zhang L, Moskovitz M, Piscatelli S, Longaker MT, Siebert JW. Hemodynamic study of different angled end-to-side anastomoses. Microsurgery 1995; 16 (2) 114-117
  • 10 Samaha FJ, Oliva A, Buncke GM, Buncke HJ, Siko PP. A clinical study of end-to-end versus end-to-side techniques for microvascular anastomosis. Plast Reconstr Surg 1997; 99 (4) 1109-1111
  • 11 Gao XS, Gao JH, Zhan HL. Experimental end-to-side anastomosis of arteries less than one millimeter in diameter and clinical applications. Ann Plast Surg 1985; 15 (4) 352-355
  • 12 Ikuta Y, Watari S, Kawamura K, Shima R, Matsuishi Y. Free flap transfers by end-to-side arterial anastomosis. Br J Plast Surg 1975; 28 (1) 1-7
  • 13 Nam DA, Roberts III TL, Acland RD. An experimental study of end-to-side microvascular anastomosis. Surg Gynecol Obstet 1978; 147 (3) 339-342
  • 14 Brennen MD, O'Brien BM. Patency rates in end to side anastomoses in the rabbit. Br J Plast Surg 1979; 32 (1) 24-30
  • 15 Fischer JP, Wink JD, Nelson JA , et al. A retrospective review of outcomes and flap selection in free tissue transfers for complex lower extremity reconstruction. J Reconstr Microsurg 2013; 29 (6) 407-416
  • 16 Dotson RJ, Bishop AT, Wood MB, Schroeder A. End-to-end versus end-to-side arterial anastomosis patency in microvascular surgery. Microsurgery 1998; 18 (2) 125-128
  • 17 Frodel JL, Trachy R, Cummings CW. End-to-end and end-to-side microvascular anastomoses: a comparative study. Microsurgery 1986; 7 (3) 117-123
  • 18 Rao VK, Morrison WA, Angus JA, O'Brien BM. Comparison of vascular hemodynamics in experimental models of microvascular anastomoses. Plast Reconstr Surg 1983; 71 (2) 241-247
  • 19 Khouri RK, Shaw WW. Reconstruction of the lower extremity with microvascular free flaps: a 10-year experience with 304 consecutive cases. J Trauma 1989; 29 (8) 1086-1094
  • 20 Haddock NT, Weichman KE, Reformat DD, Kligman BE, Levine JP, Saadeh PB. Lower extremity arterial injury patterns and reconstructive outcomes in patients with severe lower extremity trauma: a 26-year review. J Am Coll Surg 2010; 210 (1) 66-72
  • 21 Serletti JM, Deuber MA, Guidera PM , et al. Atherosclerosis of the lower extremity and free-tissue reconstruction for limb salvage. Plast Reconstr Surg 1995; 96 (5) 1136-1144
  • 22 Moran SL, Illig KA, Green RM, Serletti JM. Free-tissue transfer in patients with peripheral vascular disease: a 10-year experience. Plast Reconstr Surg 2002; 109 (3) 999-1006
  • 23 Kolbenschlag J, Hellmich S, Germann G, Megerle K. Free tissue transfer in patients with severe peripheral arterial disease: functional outcome in reconstruction of chronic lower extremity defects. J Reconstr Microsurg 2013; 29 (9) 607-614