Download PDF
Klin Monbl Augenheilkd 2015; 232(4): 556-557
DOI: 10.1055/s-0034-1396325
Der interessante Fall
Georg Thieme Verlag KG Stuttgart · New York

Cyclodialysis Cleft after Intravitreal Injection of Ranibzumab – Diagnosis and Management

Zyklodialyse nach intravitrealer Injektion mit Ranibizumab – Diagnose und Management
S. C. Böhni
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland (Director Prof. Dr. Dr. Michael A. Thiel)
,
J. P. Howell
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland (Director Prof. Dr. Dr. Michael A. Thiel)
,
M. K. Schmid
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland (Director Prof. Dr. Dr. Michael A. Thiel)
,
F. Bochmann
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland (Director Prof. Dr. Dr. Michael A. Thiel)
› Author Affiliations
Further Information

Publication History

received 00.00.00

accepted 00.00.00

Publication Date:
22 April 2015 (online)

Also available at
    Permissions and Reprints

Background

Since the introduction of anti-VEGF therapy for the treatment of choroidal neovascularisation, the intravitreal injection via pars plana has become an established way of accessing the eye for therapeutic reasons. When performed under operating room conditions, the incidence of post injection complications is very low [1]. However, in some cases, endophthalmitis, lens injury, toxic reactions (depending on medication), vitreous haemorrhage or retinal and choroidal detachment have been described [1], [2], [3]. In our report, we describe a case of cyclodialysis cleft and hypotony caused by an intravitreal injection with focus on the diagnostic and therapeutic challenges that were encountered.

 

  • References

  • 1 Shima C, Sakaguchi H, Gomi F et al. Complications in patients after intravitreal injection of bevacizumab. Acta Ophthalmol 2008; 86: 372-376
    CrossrefPubMedGoogle Scholar
  • 2 Meyer CH, Brinkmann CK, Helb HM. Choroidal detachment after an uneventful intravitreal injection. J Ocul Pharmacol Ther 2010; 26: 305-307
    CrossrefPubMedGoogle Scholar
  • 3 Patel RD, Momi RS, Hariprasad SM. Review of ranibizumab trials for neovascular age-related macular degeneration. Semin Ophthalmol 2011; 26: 372-379
    CrossrefPubMedGoogle Scholar
  • 4 Dahrab MM, Laroche GR. Error of calibration in ophthalmic calipers: a source of significant clinical errors. Can J Ophtalmol 2011; 46: 510-512
    PubMedGoogle Scholar
  • 5 Knecht PB, Michels S, Sturm V et al. Tunnelled versus straight intravitreal injection: intraocular pressure changes, vitreous reflux, and patient discomfort. Retina 2009; 29: 1175-1181
    CrossrefPubMedGoogle Scholar
  • 6 Frenkel RE, Haji SA, La M et al. A protocol for the retina surgeonʼs safe initial intravitreal injections. Clin Ophthalmol 2010; 4: 1279-1285
    PubMedGoogle Scholar
  • 7 Ioannidis AS, Barton K. Cyclodialysis cleft: causes and repair. Curr Opin Ophthalmol 2010; 21: 150-154
    CrossrefPubMedGoogle Scholar