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Semin Thromb Hemost 2012; 38(08): 908-910
DOI: 10.1055/s-0032-1330054
Erratum
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Testosterone, Hemostasis, and Cardiovascular Diseases in Men

Ellen Brodin
1   Hematological Research Group (HERG), University of Tromsø, Tromsø, Norway
3   Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
,
Torkel Vikan
2   Endocrine Research Group, Department of Clinical Medicine, University of Tromsø, Tromsø, Norway
3   Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
,
John-Bjarne Hansen
1   Hematological Research Group (HERG), University of Tromsø, Tromsø, Norway
3   Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
,
Johan Svartberg
2   Endocrine Research Group, Department of Clinical Medicine, University of Tromsø, Tromsø, Norway
3   Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
› Author Affiliations
Further Information

Publication History

Publication Date:
05 November 2012 (online)

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Correction to:

Testosterone, Hemostasis, and Cardiovascular Diseases in MenSemin Thromb Hemost 2011; 37(01): 087-094
DOI: 10.1055/s-0030-1270075

The publisher regrets an error in data in Table 1 and Reference 36 in the above article in Seminars in Thrombosis & Hemostasis, Volume 37, Number 1, 2011, p. 90 and p. 93, respectively. The correct table and reference are given below.

Table 1

Studies on testosterone, tissue factor–induced coagulation, and fibrinolysis

References

Study design

Study population

No. of patients

Major findings

Agledahl et al19

Case–control

Hypogonadal elderly men and controls (60–80 years of age)

37 vs. 41

Low T levels are associated with lower levels of TFPI Ag and shorter initiation phase of coagulation

Agledahl et al22

Double-blind placebo controlled (48 wk)

Hypogonadal elderly men (60–80 years of age)

26

T treatment did neither cause significant changes in thrombin generation ex vivo nor change plasma levels of TFPI Ag

Bonithon-Kopp et al32

Cross-sectional

Healthy middle-aged men

251

T correlated negatively to FVII Ac and α 2-antiplasmin. No association between T, fibrinogen, and AT levels

De Pergola et al34

Case–control cross-sectional

Healthy men with BMI > 25 and nonobese controls

40 vs. 24

Men with lower free T in serum have higher fibrinogen and FVII Ag levels

Phillips et al36

Observational cross-sectional

Men with CVD without previously AMI

34

T correlated negatively with fibrinogen and PAI-1 levels

Yang et al37

Cross-sectional

Healthy men with BMI < 26

48

T correlated negatively with fibrinogen and PAI-1 levels

Glueck et al38

Observational cross-sectional

Hyperlipidemic men

55

T independent inverse predictor of fibrinogen and tPA Ag

Pugh et al39

Prospective Case–control

Men with AMI and healthy controls

22 vs. 8

Total and free T fell acutely following AMI with elevation of PAI-1 and tPA Ac

Smith et al45

Double-blind placebo-controlled (8 wk)

Men with stable angina

46

T treatment did not change fibrinogen, tPA, or PAI-1 activity

Anderson et al44

Double-blind placebo-controlled (52 wk)

Healthy young men

32

T treatment reduced fibrinogen levels. AT and F1.2 rose initially during treatment, and levels of PC, PS, and PAI-1 fell but returned to pretreatment levels during continued treatment

Abbreviations: Ag, antigen; AMI, acute myocardial infarction; AT, antithrombin; BMI, body mass index; CVD, coronary vascular disease; F, factor; F1.2, fragment 1 and 2; FVII Ac, factor VII activity; PAI-I, plasminogen activator inhibitor; PC, protein C; PS, protein S; T, testosterone; TFPI Ag, tissue factor pathway inhibitor antigen; tPA ac, tissue plasminogen activator activity.


Reference

36 Phillips GB, Pinkernell BH, Jing TY. The association of hypotestosteronemia with coronary artery disease in men. Arterioscler Thromb 1994;14(5):701–706