Primary signet cell carcinoma of the prostate: a case report

Primary signet cell carcinoma of the prostate is very rare histological variant and usually originates from the stomach, colon, and pancreas. This malignancy was first reported in 1979 and there have been case series with small numbers of patients and case reports in the literature. Signet cell carcinoma of the prostate has a poor outcome when compared to classic prostate adenocarcinoma. A case of primary signet cell carcinoma of the prostate that was treated with maximal androgen deprivation therapy with zoledronic acid is reported.