01.09.2012 | short review | Ausgabe 3/2012

Primary central nervous system lymphoma: update and current approach
- Zeitschrift:
- memo - Magazine of European Medical Oncology > Ausgabe 3/2012
Abstract
Primary central nervous system lymphoma (PCNSL) is a rare type of lymphoma that requires a specialised approach to management. An initial evaluation should determine the extent of disease within the CNS compartment and must exclude the presence of systemic lymphoma. Methotrexate (MTX)-based chemotherapy is the standard of care but questions remain about the optimal drugs for use in conjunction with MTX as well as the best approach to consolidation. Furthermore, several special populations may require a modified approach to therapy.