Skip to main content
main-content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Erschienen in: Wiener klinische Wochenschrift 7-8/2013

01.04.2013 | original article

Prevalence and associations of potentially inappropriate prescriptions in Austrian nursing home residents: secondary analysis of a cross-sectional study

verfasst von: MD Eva Mann, Dr. Burkhard Haastert, MagPharm Birgit Böhmdorfer, MD Thomas Frühwald, MD Prof. Bernhard Iglseder, MD Prof. Regina Roller-Wirnsberger, Prof. Dr. Phil Gabriele Meyer

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 7-8/2013

Einloggen, um Zugang zu erhalten
share
TEILEN

Summary

Background

Potentially inappropriate prescriptions (PIP) are an important cause of adverse medication-related events and increases morbidity, hospitalization, and health care costs, especially in nursing home residents. However, little is known about the associations between PIP and residents’ characteristics.

Objective

The aim of our study was to analyse the prevalence and associations of PIP with residents’ and facilities’ characteristics.

Methods

We performed a secondary analysis of a cross-sectional study with 48 out of 50 eligible nursing homes and 1,844 out of 2,005 eligible residents in a defined rural-urban area in Austria. The Austrian list of potentially inappropriate medications was applied for the evaluation of inappropriate prescribing. Cluster-adjusted multiple regression analysis was used to investigate institutional and residents’ characteristics associated with PIP.

Results

Mean cluster-adjusted prevalence of residents with at least one PIP was 70.3 % (95 % CI 67.2–73.4). The number of residents with at least one psychotropic PIP was 1.014 (55 %). The most often prescribed PIP were Prothipendyl (25.9 % residents), Lorazepam (14.5 %) and Diclofenac (6.1 %). Multiple regression analysis showed an inverse association of PIP with cognitive impairment and significant positive associations with permanent restlessness and permanent negative attitude. The associations of PIP with age and male gender were inconsistent. No significant associations were found for PIP and the ratio of staff nurses to residents.

Conclusions

Our study results confirm that PIP is highly prevalent in the nursing home population. These results urgently call for effective interventions. Initiatives and successful interventions performed in other countries could serve as examples for safer prescribing in residents in Austria.
Literatur
1.
Zurück zum Zitat Onder G, Liperoti R, Fialova D, et al. SHELTER project. J Gerontol A Biol Sci Med Sci. 2012;67(6):698–704. PubMedCrossRef Onder G, Liperoti R, Fialova D, et al. SHELTER project. J Gerontol A Biol Sci Med Sci. 2012;67(6):698–704. PubMedCrossRef
2.
Zurück zum Zitat Kojima G, Bell C, Tamura B, et al. Reducing cost by reducing polypharmacy: the polypharmacy outcomes project. JAMDA. 2012;13(9):818e11–5. Kojima G, Bell C, Tamura B, et al. Reducing cost by reducing polypharmacy: the polypharmacy outcomes project. JAMDA. 2012;13(9):818e11–5.
3.
Zurück zum Zitat Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol. 2004;57(1):6–14. PubMedCrossRef Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol. 2004;57(1):6–14. PubMedCrossRef
4.
Zurück zum Zitat Leendertse AJ, Egberts AC, Stoker LJ, Van Den Bernt PM. HARM study Group. Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med. 2008;168(17):1890–6. PubMedCrossRef Leendertse AJ, Egberts AC, Stoker LJ, Van Den Bernt PM. HARM study Group. Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med. 2008;168(17):1890–6. PubMedCrossRef
5.
Zurück zum Zitat Berdot S, Bertrand M, Dartigues JF, et al. Inappropriate medication use and risk of falls-a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009;9:30. PubMedCrossRef Berdot S, Bertrand M, Dartigues JF, et al. Inappropriate medication use and risk of falls-a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009;9:30. PubMedCrossRef
6.
Zurück zum Zitat Fick DM, Mion LC, Beers MH, Waller JL. Health outcomes associated with potentially inappropriate medication use in older adults. Res Nurs Health. 2008;31(1):42–51. PubMedCrossRef Fick DM, Mion LC, Beers MH, Waller JL. Health outcomes associated with potentially inappropriate medication use in older adults. Res Nurs Health. 2008;31(1):42–51. PubMedCrossRef
7.
Zurück zum Zitat Albert SM, Colombi A, Hanlon J. Potentially inappropriate medications and risk of hospitalization in retirees: analysis of a US retiree health claims database. Drugs Aging. 2010;27(5):407–15. PubMedCrossRef Albert SM, Colombi A, Hanlon J. Potentially inappropriate medications and risk of hospitalization in retirees: analysis of a US retiree health claims database. Drugs Aging. 2010;27(5):407–15. PubMedCrossRef
8.
Zurück zum Zitat Ruggiero C, Dell’Auilla G, Gasperini B, et al. Potentially inappropriate drug prescriptions and risk of hospitalizations among older, Italian, nursing home residents: the ULISSE project. Drugs Aging. 2010;27(9):747–58. PubMedCrossRef Ruggiero C, Dell’Auilla G, Gasperini B, et al. Potentially inappropriate drug prescriptions and risk of hospitalizations among older, Italian, nursing home residents: the ULISSE project. Drugs Aging. 2010;27(9):747–58. PubMedCrossRef
9.
Zurück zum Zitat Lin HY, Liao CC, Cheng SH, Wang PC, Hsueh YS. Association of potentially inappropriate medication use with adverse outcomes in ambulatory elderly patients with chronic diseases: experience in a Taiwanese medical setting. Drugs Aging. 2008;25(1):49–59. PubMedCrossRef Lin HY, Liao CC, Cheng SH, Wang PC, Hsueh YS. Association of potentially inappropriate medication use with adverse outcomes in ambulatory elderly patients with chronic diseases: experience in a Taiwanese medical setting. Drugs Aging. 2008;25(1):49–59. PubMedCrossRef
10.
Zurück zum Zitat Lau DT, Kasper JD, Potter EB, Lyles A, Bennett RG. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch Intern Med. 2005;165(1):68–74. PubMedCrossRef Lau DT, Kasper JD, Potter EB, Lyles A, Bennett RG. Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents. Arch Intern Med. 2005;165(1):68–74. PubMedCrossRef
11.
Zurück zum Zitat Fu AZ, Jiang JZ, Reeves JH, Fincham JE, Liu GG, Perri M 3rd. Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderly. Med Care. 2007;45(5):472–6. PubMedCrossRef Fu AZ, Jiang JZ, Reeves JH, Fincham JE, Liu GG, Perri M 3rd. Potentially inappropriate medication use and healthcare expenditures in the US community-dwelling elderly. Med Care. 2007;45(5):472–6. PubMedCrossRef
12.
Zurück zum Zitat Barnett K, McCowan C, Evans JM, Gillespie ND, Davey PG, Fahey T. Prevalence and outcomes of use of potentially inappropriate medications in older people: cohort study stratified by residence in nursing home or in the community. BMJ Qual Saf. 2011;20(3):275–81. PubMedCrossRef Barnett K, McCowan C, Evans JM, Gillespie ND, Davey PG, Fahey T. Prevalence and outcomes of use of potentially inappropriate medications in older people: cohort study stratified by residence in nursing home or in the community. BMJ Qual Saf. 2011;20(3):275–81. PubMedCrossRef
13.
Zurück zum Zitat Niwata S, Yamada Y, Ikegami N. Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities. BMC Geriatr. 2006;6:1. Niwata S, Yamada Y, Ikegami N. Prevalence of inappropriate medication using Beers criteria in Japanese long-term care facilities. BMC Geriatr. 2006;6:1.
14.
Zurück zum Zitat Stafford AC, Alswayan MS, Tenni PC. Inappropriate prescribing in older residents of Australian care homes. J Clin Pharm Ther. 2011;36(1):33–44. PubMedCrossRef Stafford AC, Alswayan MS, Tenni PC. Inappropriate prescribing in older residents of Australian care homes. J Clin Pharm Ther. 2011;36(1):33–44. PubMedCrossRef
15.
Zurück zum Zitat Kölzsch M, Kopke K, Fischer T, et al. Prescribing of inappropriate medication in nursing home residents in Germany according to a French consensus list: a cross-sectional cohort study. Pharmacoepidemiol Drug Saf. 2011;20(1):12–9. PubMedCrossRef Kölzsch M, Kopke K, Fischer T, et al. Prescribing of inappropriate medication in nursing home residents in Germany according to a French consensus list: a cross-sectional cohort study. Pharmacoepidemiol Drug Saf. 2011;20(1):12–9. PubMedCrossRef
16.
Zurück zum Zitat Haasum Y, Fastbom J, Johnell K. Institutionalization as a risk factor for inappropriate drug use in the elderly: a Swedish nationwide register-based study. Ann Pharmacother. 2012;46(3):339–46. PubMedCrossRef Haasum Y, Fastbom J, Johnell K. Institutionalization as a risk factor for inappropriate drug use in the elderly: a Swedish nationwide register-based study. Ann Pharmacother. 2012;46(3):339–46. PubMedCrossRef
17.
Zurück zum Zitat Johnell K, Weithoft GR, Fastbom, J. Sex differences in inappropriate drug use: a register-based study of over 600,000 older people. Ann Pharmacother. 2009;43(7):1233–8. PubMedCrossRef Johnell K, Weithoft GR, Fastbom, J. Sex differences in inappropriate drug use: a register-based study of over 600,000 older people. Ann Pharmacother. 2009;43(7):1233–8. PubMedCrossRef
18.
Zurück zum Zitat Mann E, Köpke S, Haastert B, Pitkälä K, Meyer G. Psychotropic drug use among nursing home residents in Austria: a cross-sectional study. BMC Geriatr. 2009;9:18. PubMedCrossRef Mann E, Köpke S, Haastert B, Pitkälä K, Meyer G. Psychotropic drug use among nursing home residents in Austria: a cross-sectional study. BMC Geriatr. 2009;9:18. PubMedCrossRef
19.
Zurück zum Zitat Richter T, Mann E, Meyer G, Haastert B, Köpke S. Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts. JAMDA. 2012;13(2):187.e7–187.e13. Richter T, Mann E, Meyer G, Haastert B, Köpke S. Prevalence of psychotropic medication use among German and Austrian nursing home residents: a comparison of 3 cohorts. JAMDA. 2012;13(2):187.e7–187.e13.
20.
Zurück zum Zitat Austrian Ministry of Social Welfare. Federal Act on Nursing Care, 110, 51. (Bundespflegegesetz, BGBl. 110/1993, text of 19 Jan. 1993) (SOZDOK ed.). Vienna, 51. 1998. Austrian Ministry of Social Welfare. Federal Act on Nursing Care, 110, 51. (Bundespflegegesetz, BGBl. 110/1993, text of 19 Jan. 1993) (SOZDOK ed.). Vienna, 51. 1998.
21.
Zurück zum Zitat Köhler L, Weyerer S, Schäufele M. Proxy screening tools improve the recognition of dementia in old-age homes: results of a validation study. Age Aging. 2007;36:549–54. CrossRef Köhler L, Weyerer S, Schäufele M. Proxy screening tools improve the recognition of dementia in old-age homes: results of a validation study. Age Aging. 2007;36:549–54. CrossRef
22.
Zurück zum Zitat Cohen-Mansfield J. Agitated behaviours in the elderly. II. Preliminary results in the cognitively deteriorated. JAGS. 1986;34(10):722–7. Cohen-Mansfield J. Agitated behaviours in the elderly. II. Preliminary results in the cognitively deteriorated. JAGS. 1986;34(10):722–7.
23.
Zurück zum Zitat Mann E, Böhmdorfer B, Frühwald T, Roller-Wirnsberger RE, Dovjak P, Hofer-Dückelmann C, et al. Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list. WKW. 2012;124(5–6):160–9. Mann E, Böhmdorfer B, Frühwald T, Roller-Wirnsberger RE, Dovjak P, Hofer-Dückelmann C, et al. Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list. WKW. 2012;124(5–6):160–9.
24.
Zurück zum Zitat Donner A, Klar N. Design and Analysis of Cluster Randomization. Trials in health research. London: Arnold; 2000. Donner A, Klar N. Design and Analysis of Cluster Randomization. Trials in health research. London: Arnold; 2000.
25.
Zurück zum Zitat Rogers WH. Regression standard errors in clustered samples. Stat Tech Bull. 1993;13:19–23. Rogers WH. Regression standard errors in clustered samples. Stat Tech Bull. 1993;13:19–23.
26.
Zurück zum Zitat Williams RL. A note on robust variance estimation for cluster-correlated data. Biometrics. 2000;56(2):645–6. PubMedCrossRef Williams RL. A note on robust variance estimation for cluster-correlated data. Biometrics. 2000;56(2):645–6. PubMedCrossRef
27.
Zurück zum Zitat Bergman A, Olsson J, Carlstein A, Waern M, Fastbom J. Evaluation of the quality of drug therapy among elderly patients in nursing homes. Scand J Prim Health Care. 2007;25(1):9–14. PubMedCrossRef Bergman A, Olsson J, Carlstein A, Waern M, Fastbom J. Evaluation of the quality of drug therapy among elderly patients in nursing homes. Scand J Prim Health Care. 2007;25(1):9–14. PubMedCrossRef
28.
Zurück zum Zitat Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self-controlled case series studies. BMJ. 2008;337:a1227. CrossRef Douglas IJ, Smeeth L. Exposure to antipsychotics and risk of stroke: self-controlled case series studies. BMJ. 2008;337:a1227. CrossRef
29.
Zurück zum Zitat Gill SS, Bronskill SE, Normand SL, et al. Antipsychotic drug use and mortality in older adults with dementia. Ann Intern Med. 2007;146(11):775–86. PubMedCrossRef Gill SS, Bronskill SE, Normand SL, et al. Antipsychotic drug use and mortality in older adults with dementia. Ann Intern Med. 2007;146(11):775–86. PubMedCrossRef
30.
Zurück zum Zitat Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA. 2005;294(15):1934–43. PubMedCrossRef Schneider LS, Dagerman KS, Insel P. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA. 2005;294(15):1934–43. PubMedCrossRef
31.
Zurück zum Zitat Tannenbaum C, Paquette A, Hilmer S, Holroyd-Leduc J, Carnahan R. A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs. Drugs Aging. 2012;29(8):639–58. PubMed Tannenbaum C, Paquette A, Hilmer S, Holroyd-Leduc J, Carnahan R. A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs. Drugs Aging. 2012;29(8):639–58. PubMed
32.
Zurück zum Zitat Lader M. Benzodiazepine harm: how can it be reduced. Brit J Clin Pharmacol. 2012;doi:10.1111/j.1365–2125.2012.04418.x (Epub ahead of print). Lader M. Benzodiazepine harm: how can it be reduced. Brit J Clin Pharmacol. 2012;doi:10.1111/j.1365–2125.2012.04418.x (Epub ahead of print).
33.
Zurück zum Zitat Huang AR, Mallet L, Rochefort CM, Equale T, Buckeridge DL, Tamblyn R. Medication-related falls in the elderly: causative factors and preventive strategies. Drugs Aging. 2012;29(5):359–76. PubMedCrossRef Huang AR, Mallet L, Rochefort CM, Equale T, Buckeridge DL, Tamblyn R. Medication-related falls in the elderly: causative factors and preventive strategies. Drugs Aging. 2012;29(5):359–76. PubMedCrossRef
34.
Zurück zum Zitat Hosia-Randell HM, Muuringen SM, Pitkälä KH. Exposure to potentially inappropriate drugs and drug-drug interactions in elderly nursing home residents in Helsinki, Finland: a cross-sectional study. Drugs Aging. 2008;25(8):683–92. PubMedCrossRef Hosia-Randell HM, Muuringen SM, Pitkälä KH. Exposure to potentially inappropriate drugs and drug-drug interactions in elderly nursing home residents in Helsinki, Finland: a cross-sectional study. Drugs Aging. 2008;25(8):683–92. PubMedCrossRef
35.
Zurück zum Zitat Raschetti R, Morgutti M, Menniti-Ippolit F, et al. Suspected adverse drug events requiring emergency department visits or hospital admissions. Eur J Clin Pharmacol. 1999;54(12):959–63. PubMedCrossRef Raschetti R, Morgutti M, Menniti-Ippolit F, et al. Suspected adverse drug events requiring emergency department visits or hospital admissions. Eur J Clin Pharmacol. 1999;54(12):959–63. PubMedCrossRef
36.
Zurück zum Zitat Yu MK, Lyles CR, Bent-Shaw LA, Young BA. Risk factor, age and sex difference in chronic kidney disease prevalence in a diabetic cohort. Am J Nephrol. 2012;36(3):245–51. PubMedCrossRef Yu MK, Lyles CR, Bent-Shaw LA, Young BA. Risk factor, age and sex difference in chronic kidney disease prevalence in a diabetic cohort. Am J Nephrol. 2012;36(3):245–51. PubMedCrossRef
37.
Zurück zum Zitat Vega J, Goecke H, Méndez GP, Guarda FJ. Nephrotic syndrome and acute tubular necrosis due to meloxicam use. Ren Fail. 2012;34(10):1344–7. PubMedCrossRef Vega J, Goecke H, Méndez GP, Guarda FJ. Nephrotic syndrome and acute tubular necrosis due to meloxicam use. Ren Fail. 2012;34(10):1344–7. PubMedCrossRef
38.
Zurück zum Zitat Kristensen SL, Fosbol EL, Kamper AL, et al. Use of nonsteroidal anti-inflammarotry drugs prior to chronic renal replacement therapy initiation: a nationwide study. Pharmacoepidemiol Drug Saf. 2012;21(4):428–34. PubMedCrossRef Kristensen SL, Fosbol EL, Kamper AL, et al. Use of nonsteroidal anti-inflammarotry drugs prior to chronic renal replacement therapy initiation: a nationwide study. Pharmacoepidemiol Drug Saf. 2012;21(4):428–34. PubMedCrossRef
39.
Zurück zum Zitat Savva GM, Matthews FE, Davidson JE, McKeith I, Brayne C. Prevalence, correlates and course of behavioural and psychological symptoms of dementia in the population. Br J Psychiatry. 2009;194(3):212–9. PubMedCrossRef Savva GM, Matthews FE, Davidson JE, McKeith I, Brayne C. Prevalence, correlates and course of behavioural and psychological symptoms of dementia in the population. Br J Psychiatry. 2009;194(3):212–9. PubMedCrossRef
40.
Zurück zum Zitat Cerejeira J, Lagarto L, Mukaetova-Ladinska EB. Behavioural and psychological symptoms of dementia. Front Neurol. 2012;3:73 (Epub ahead of print). PubMedCrossRef Cerejeira J, Lagarto L, Mukaetova-Ladinska EB. Behavioural and psychological symptoms of dementia. Front Neurol. 2012;3:73 (Epub ahead of print). PubMedCrossRef
41.
Zurück zum Zitat Levy K, Lanctot KL, Farber SB, Li A, Herrmann, N. Does pharmacological treatment of neuropsychiatric symptoms in Alzheimer’s disease relieve caregiver burden. Drugs Aging. 2012;29(3):167–79. Levy K, Lanctot KL, Farber SB, Li A, Herrmann, N. Does pharmacological treatment of neuropsychiatric symptoms in Alzheimer’s disease relieve caregiver burden. Drugs Aging. 2012;29(3):167–79.
42.
Zurück zum Zitat Zuidema SU, De Jonghe JF, Verhey FR, Koopmans RT. Psychotropic drug prescription in nursing home patients with dementia: influence of environmental correlates and staff distress on physicians’ prescription behaviour. Int Psychogeriatr. 2011;23(10):1632–9. PubMedCrossRef Zuidema SU, De Jonghe JF, Verhey FR, Koopmans RT. Psychotropic drug prescription in nursing home patients with dementia: influence of environmental correlates and staff distress on physicians’ prescription behaviour. Int Psychogeriatr. 2011;23(10):1632–9. PubMedCrossRef
43.
Zurück zum Zitat Gauthier S, Cummings J, Ballard C, et al. Management of behavioural symptoms in Alzheimer’s disease. Int Psychogeriatr. 2010;22(3):346–72. PubMedCrossRef Gauthier S, Cummings J, Ballard C, et al. Management of behavioural symptoms in Alzheimer’s disease. Int Psychogeriatr. 2010;22(3):346–72. PubMedCrossRef
44.
Zurück zum Zitat Ballard C, Day S, Sharp S, Wing C, Sorensen S. Neuropsychiatric symptoms in dementia: importance and treatment considerations. Int Rev Psychiatry. 2008;20(4):396–404. PubMedCrossRef Ballard C, Day S, Sharp S, Wing C, Sorensen S. Neuropsychiatric symptoms in dementia: importance and treatment considerations. Int Rev Psychiatry. 2008;20(4):396–404. PubMedCrossRef
45.
Zurück zum Zitat Beers MH, Ouslander JG, Rollingher J, Reuben DB, Brooks J, Beck JC. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Int Med. 1991;151(9):1825–32. CrossRef Beers MH, Ouslander JG, Rollingher J, Reuben DB, Brooks J, Beck JC. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Int Med. 1991;151(9):1825–32. CrossRef
46.
Zurück zum Zitat McLeod PJ, Huang A, Tamblyn RM, Gayton DC. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. CMAJ. 1997;156:385–91. PubMed McLeod PJ, Huang A, Tamblyn RM, Gayton DC. Defining inappropriate practices in prescribing for elderly people: a national consensus panel. CMAJ. 1997;156:385–91. PubMed
47.
Zurück zum Zitat Laroche ML, Charmes JP, Merle L. Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol. 2007;63(8):725–31. PubMedCrossRef Laroche ML, Charmes JP, Merle L. Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol. 2007;63(8):725–31. PubMedCrossRef
48.
Zurück zum Zitat Gallagher P, Ryan C, Byrne S, Kennedy J, O’Mahony D. Screening tool of older person’s prescriptions (STOPP) and screening tool to alert doctors to right treatment (START). Consensus validation. Int J Clin Pharmacol Therap. 2008;46(2):72–83. Gallagher P, Ryan C, Byrne S, Kennedy J, O’Mahony D. Screening tool of older person’s prescriptions (STOPP) and screening tool to alert doctors to right treatment (START). Consensus validation. Int J Clin Pharmacol Therap. 2008;46(2):72–83.
49.
Zurück zum Zitat Holt S, Schmiedl S, Thürmann PA. Potentially inappropriate medications in the elderly: the PRISCUS List. Dtsch Arztebl. 2010;107(31–32):543–51. Holt S, Schmiedl S, Thürmann PA. Potentially inappropriate medications in the elderly: the PRISCUS List. Dtsch Arztebl. 2010;107(31–32):543–51.
50.
Zurück zum Zitat American Geriatrics Society 2012 Beers Criteria update expert panel. American Society updated Beers Criteria for potentially inappropriate medication use in older adults. JAGS. 2012;60(4):616–31. CrossRef American Geriatrics Society 2012 Beers Criteria update expert panel. American Society updated Beers Criteria for potentially inappropriate medication use in older adults. JAGS. 2012;60(4):616–31. CrossRef
52.
Zurück zum Zitat Richter T, Meyer G, Möhler R, Köpke S. Psychosocial interventions for reducing antipsychotic medication in care home residents. Cochrane Database Syst Rev. 2012 Dec;12:12:CD008634. doi:10.1002/14651858.CD008634.pub2. Richter T, Meyer G, Möhler R, Köpke S. Psychosocial interventions for reducing antipsychotic medication in care home residents. Cochrane Database Syst Rev. 2012 Dec;12:12:CD008634. doi:10.1002/14651858.CD008634.pub2.
53.
Zurück zum Zitat Fossey J, Ballard C, Juszczak E, James I, Alder N, Jacoby R, Howard R. Effect of enhanced psychosocial care on antipsychotic use in nursing home residents. BMJ. 2006;332:756–61. PubMedCrossRef Fossey J, Ballard C, Juszczak E, James I, Alder N, Jacoby R, Howard R. Effect of enhanced psychosocial care on antipsychotic use in nursing home residents. BMJ. 2006;332:756–61. PubMedCrossRef
54.
Zurück zum Zitat Pitkälä K, Juola A, Soini H, Laakkonen M, Kauriainen H, Teramura-Gronblad M, Finne-Soveri H, Bjorkman M. Reducing inappropriate, anticholinergic and psychotropic drugs among older residents in assisted living facilities: study protocol for a randomized controlled trial. Trials. 2102;13:85. Pitkälä K, Juola A, Soini H, Laakkonen M, Kauriainen H, Teramura-Gronblad M, Finne-Soveri H, Bjorkman M. Reducing inappropriate, anticholinergic and psychotropic drugs among older residents in assisted living facilities: study protocol for a randomized controlled trial. Trials. 2102;13:85.
55.
Zurück zum Zitat Müller C, Wilm S, Thürmann P, Thiem U, Hummers-Pradier E, Theile G. Die RIME Studie-eine clusterrandomisierte kontrollierte Studie zur Reduktion von potentiell inadäquater Medikation in der Hausarztpraxis. Düsseldorf: German Medical Science GMS Publishing House; 2011 (Doc1 1form067). Müller C, Wilm S, Thürmann P, Thiem U, Hummers-Pradier E, Theile G. Die RIME Studie-eine clusterrandomisierte kontrollierte Studie zur Reduktion von potentiell inadäquater Medikation in der Hausarztpraxis. Düsseldorf: German Medical Science GMS Publishing House; 2011 (Doc1 1form067).
56.
Zurück zum Zitat PRIMA-eDS. Polypharmacy in chronic diseases: reduction of inappropriate medication and adverse drug events in elderly populations by electronic decision support. European Commission Project Number 305388. http://​ec.​europa.​eu/​research/​health/​medical-research/​human-development-and-ageing/​projects/​prima-eds_​en.​html.​ Accessed 8 Feb 2013. PRIMA-eDS. Polypharmacy in chronic diseases: reduction of inappropriate medication and adverse drug events in elderly populations by electronic decision support. European Commission Project Number 305388. http://​ec.​europa.​eu/​research/​health/​medical-research/​human-development-and-ageing/​projects/​prima-eds_​en.​html.​ Accessed 8 Feb 2013.
Metadaten
Titel
Prevalence and associations of potentially inappropriate prescriptions in Austrian nursing home residents: secondary analysis of a cross-sectional study
verfasst von
MD Eva Mann
Dr. Burkhard Haastert
MagPharm Birgit Böhmdorfer
MD Thomas Frühwald
MD Prof. Bernhard Iglseder
MD Prof. Regina Roller-Wirnsberger
Prof. Dr. Phil Gabriele Meyer
Publikationsdatum
01.04.2013
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 7-8/2013
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-013-0342-2

Weitere Artikel der Ausgabe 7-8/2013

Wiener klinische Wochenschrift 7-8/2013 Zur Ausgabe

MUW researcher of the month

Researcher of the Month