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Erschienen in: Wiener klinische Wochenschrift 7-8/2020

14.02.2020 | original article

Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores

A retrospective study

verfasst von: MD Mustafa Kaplan, MD Tolga Duzenli, MD Alpaslan Tanoglu, MD Basak Cakir Guney, MD Yesim Onal Tastan, MD Hatice Selcen Bicer

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 7-8/2020

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Summary

Objective

To investigate the prognostic value of the presepsin:albumin ratio and C‑reactive protein:albumin ratio in patients with sepsis in the intensive care unit (ICU).

Methods

A total of 228 (129 males and 99 females) patients with newly diagnosed sepsis were included in the study. The relationship between the C‑reactive protein:albumin ratio, presepsin:albumin ratio, clinicopathologic parameters, and overall survival were investigated. The associations between C‑reactive protein:albumin ratio and presepsin:albumin ratio were evaluated alongside other inflammation-based prognostic scores such as quick Sepsis Related Organ Failure Assessment (qSOFA).

Results

The presepsin:albumin ratio was significantly higher in non-survivors (p < 0.01). Patients with a high presepsin:albumin ratio had worse overall survival compared with patients with high C‑reactive protein:albumin ratio levels (p < 0.001).

Conclusion

Presepsin and presepsin:albumin ratio are markers of adverse prognosis in patients with sepsis and are superior to C‑reactive protein and C‑reactive protein:albumin ratio for this purpose. Presepsin:albumin ratio may be a novel marker of poor prognosis in patients with sepsis in intensive care units.
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Metadaten
Titel
Presepsin:albumin ratio and C-reactive protein:albumin ratio as novel sepsis-based prognostic scores
A retrospective study
verfasst von
MD Mustafa Kaplan
MD Tolga Duzenli
MD Alpaslan Tanoglu
MD Basak Cakir Guney
MD Yesim Onal Tastan
MD Hatice Selcen Bicer
Publikationsdatum
14.02.2020
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 7-8/2020
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-020-01618-9

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