01.08.2014 | Short Communication
Poor sensitivity of 99mTc-labeled ubiquicidin scintigraphy in diagnosis of acute appendicitis
Erschienen in: European Surgery | Ausgabe 4/2014
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Background
Ubiquicidin 29–41 (UBI) is an antimicrobial peptide.
Methods
In total eight men and two women with high probability of acute appendicitis were serially imaged for up to 30 min after the intravenous administration of 370 MBq of 99mTc-UBI, before surgical exploration
Results
The scan showed mild to moderate increased uptake in the right lower quadrant in six patients. Quantitative analysis failed to show any difference between suppurative and gangrenous appendicitis.
Conclusion
99mTc-UBI scintigraphy has 20 % sensitivity for diagnosis of acute appendicitis.
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