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Erschienen in: Wiener Medizinische Wochenschrift 13-14/2012

01.07.2012 | Kalzium in der kardialen Pathophysiologie

Pharmacology of myocardial calcium-handling

verfasst von: Julia Vogler, MD, Lars Eckardt, MD

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 13-14/2012

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Summary

Disturbed myocardial calcium (Ca+) handling is one of the pathophysiologic hallmarks of cardiovascular diseases such as congestive heart failure, cardiac hypertrophy, and certain types of tachyarrhythmias. Pharmacologic treatment of these diseases thus focuses on restoring myocardial Ca2+ homeostasis by interacting with Ca2+-dependent signaling pathways. In this article, we review the currently used pharmacologic agents that are able to restore or maintain myocardial Ca2+ homeostasis and their mechanism of action as well as emerging new substances.
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Metadaten
Titel
Pharmacology of myocardial calcium-handling
verfasst von
Julia Vogler, MD
Lars Eckardt, MD
Publikationsdatum
01.07.2012
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 13-14/2012
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-012-0108-x

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