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Erschienen in: Wiener klinische Wochenschrift 9-10/2018

16.01.2018 | original article

Orotracheal tube as a risk factor for lower respiratory tract infection: preliminary data from a randomised trial

verfasst von: Igor Muzlovic, Janja Perme, David Stubljar

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2018

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Summary

Purpose

The aim of the study was to investigate whether polyurethane (PU) endotracheal tubes, continuous measurements of cuff pressure and aspiration of the subglottic space as a bundle of parameters could reduce patients’ risk for developing ventilator associated pneumonia (VAP).

Methods

Two groups of patients that differed only in terms of endotracheal tubes and intubation intervention were compared. Group A was ventilated using PU tubes a with conical cuff; they also had continuous cuff pressure measurement and continuous subglottic aspiration. Group B was ventilated using PVC tubes with a cylindrical cuff; the patients underwent intermittent cuff pressure measurement and intermittent subglottic aspiration.

Results

Seven patients in group A (13.2%) and 18 in group B (36.0%) out of 103 were diagnosed with VAP. VAP patients were in general older, stayed longer in the ICU and were ventilated significantly longer compared with the patients with no VAP. Eight more patients in group B died compared with group A. Moreover, subjects in group A survived longer. Patient age, hours on mechanical ventilation, and days on an ICU were all positively associated with the occurrence of VAP.

Conclusions

Prevention parameters in ventilation (PU cuff, conical cuff, continuous subglottic drainage and continuous cuff pressure measurement) could prevent the incidence of VAP in ICU patients.
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Metadaten
Titel
Orotracheal tube as a risk factor for lower respiratory tract infection: preliminary data from a randomised trial
verfasst von
Igor Muzlovic
Janja Perme
David Stubljar
Publikationsdatum
16.01.2018
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 9-10/2018
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-017-1304-x

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