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01.12.2016 | case report | Ausgabe 23-24/2016

Wiener klinische Wochenschrift 23-24/2016

Nonbacterial thrombotic endocarditis presenting as intracerebral hemorrhage

Zeitschrift:
Wiener klinische Wochenschrift > Ausgabe 23-24/2016
Autoren:
MD Olivier Wigger, MD Stephan Windecker, MD, PhD Stefan Bloechlinger

Summary

Nonbacterial thrombotic endocarditis is a rare cause of valvular heart disease, most commonly associated with advanced malignancy. The morbidity of this kind of endocarditis lies in its tendency to embolize, while the valve function is usually preserved. The central nervous system is the most common site of embolization, leading to ischemic stroke. We report a case of nonbacterial thrombotic endocarditis complicated by intracerebral hemorrhage as the first manifestation of adenocarcinoma of the lung. The endocarditis led to severe aortic regurgitation. In view of the advanced stage of lung cancer, the patient refused further therapy. He passed away 3 weeks after first diagnosis of the adenocarcinoma.

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