Neuro-oncology 2021

In this issue of  memo (Magazine of European Medical Oncology), you will find two review articles: one on the current management of brain metastases [1] and a second one on leptomeningeal metastases [2]. Both disease manifestations of solid tumors have gained interest, mostly due to an increasing number of affected patients, an improved pathophysiological understanding and, most importantly, advances in diagnostic and therapeutic approaches. A valuable addition to the two previously mentioned articles is a statement by Dieckmann and Herrmann on the role of whole-brain radiation therapy (WBRT) in these tumor manifestations. Impressive neurocognitive deteriorations already 3 months after and increasingly in the first year after WBRT limit the indication of this modality in favour of focused irradiation or targeted therapy in accordance with the tumor entity [3]. …