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Erschienen in: Journal für Klinische Endokrinologie und Stoffwechsel 4/2018

01.12.2018 | Fallbericht

Metforminassoziierte Laktatazidose (MALA) – eine fallbasierte Darstellung

verfasst von: Dr. A. Polach, Dr. D. Parcz, Dr. B. Ritter

Erschienen in: Journal für Endokrinologie, Diabetologie und Stoffwechsel | Ausgabe 4/2018

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Auszug

Die metforminassoziierte Laktatazidose (MALA) stellt einen seltenen, aber lebensbedrohlichen Zustand mit hoher Mortalität dar. Der häufigste Auslöser ist ein akutes Nierenversagen infolge von Flüssigkeitsverlust häufig auf der Basis einer bereits vorbestehenden Niereninsuffizienz. Diese ernst zu nehmende Erkrankung macht eine Intensivbehandlung mit Korrektur der Azidose, kontinuierlichem Nierenersatzverfahren, häufig kreislaufunterstützenden Maßnahmen und eventuell auch mechanischer Ventilation zumeist unumgänglich. Eine rasche therapeutische Entscheidung und Einleitung der adäquaten therapeutischen Maßnahmen ist für das Überleben der Patienten essenziell. Wir berichten über einen Fall einer schweren lebensbedrohlichen metforminassoziierten Azidose infolge eines akuten Nierenversagens mit positivem Outcome. …
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Metadaten
Titel
Metforminassoziierte Laktatazidose (MALA) – eine fallbasierte Darstellung
verfasst von
Dr. A. Polach
Dr. D. Parcz
Dr. B. Ritter
Publikationsdatum
01.12.2018
Verlag
Springer Vienna
Erschienen in
Journal für Endokrinologie, Diabetologie und Stoffwechsel / Ausgabe 4/2018
Print ISSN: 3004-8915
Elektronische ISSN: 3004-8923
DOI
https://doi.org/10.1007/s41969-018-0048-1

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