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Erschienen in: European Surgery 1/2018

24.11.2017 | case report

Metastasis to the esophagus from primary adenocarcinoma of the lung

verfasst von: Simone Zanghì, Stefano Siboni, Emanuele Asti, Antonella Festa, Luigi Bonavina

Erschienen in: European Surgery | Ausgabe 1/2018

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Summary

Background

Metastasis to the esophagus is a rare event that can occur by direct infiltration of malignancies from nearby organs or, more infrequently, via lymphatic or hematogenous spread.

Methods

We reviewed the hospital charts of a patient presenting with dysphagia in whom a distant metastasis to the esophagus from a primary lung adenocarcinoma was documented. A review of the pertinent literature was performed.

Results

A 74 year-old man with previous history of lung cancer and transoral septum stapling for Zenker’s diverticulum presented with subtotal dysphagia and chest pain. On upper gastrointestinal endoscopy, a vegetating mass of the middle esophagus, covered by fragile and bleeding mucosa, was found. Esophageal biopsies demonstrated metastasis from a poorly differentiated lung adenocarcinoma with evidence of thyroid transcription factor (TTF) positive neoplastic cells. A computed tomography scan revealed a radiopaque mass in the upper right lung. Combination chemotherapy was initiated and a partially covered stent was placed endoscopically.

Conclusions

A distant metastatic tumor to the esophagus with mucosal infiltration is an exceptional event. In our patient, immunohistochemistry was useful to confirm the diagnosis of primary lung carcinoma.
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Metadaten
Titel
Metastasis to the esophagus from primary adenocarcinoma of the lung
verfasst von
Simone Zanghì
Stefano Siboni
Emanuele Asti
Antonella Festa
Luigi Bonavina
Publikationsdatum
24.11.2017
Verlag
Springer Vienna
Erschienen in
European Surgery / Ausgabe 1/2018
Print ISSN: 1682-8631
Elektronische ISSN: 1682-4016
DOI
https://doi.org/10.1007/s10353-017-0501-1

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