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Erschienen in: European Surgery 3/2021

07.05.2021 | perspective

Management of early-stage gallbladder cancer

verfasst von: Doris Wagner, MD, Georg Werkgartner, Klaus Kaczirek

Erschienen in: European Surgery | Ausgabe 3/2021

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Excerpt

Gallbladder cancer (GBC) is the fifth most common cancer of the gastrointestinal tract and the most common cancer of the biliary tract [1]. GBC is associated with very poor 5‑year survival rates of only 5–13% [2, 3]. These poor survival rates root in the usually advanced stage of disease at the time of diagnosis and can be attributed to the aggressive nature of GBC as well as the late onset of symptoms like jaundice or pain. Early GBC is usually defined as a tumor confined to the mucosa or the muscularis propria, which corresponds to stages T1a and T1b according to the 8th edition of the American Joint Committee on Cancer (AJCC) guidelines [4]. …
Literatur
1.
Zurück zum Zitat Cherkassky L, D’Angelica M. Gallbladder cancer: managing the incidental diagnosis. Surg Oncol Clin N Am. 2019;28(4):619–30.CrossRef Cherkassky L, D’Angelica M. Gallbladder cancer: managing the incidental diagnosis. Surg Oncol Clin N Am. 2019;28(4):619–30.CrossRef
2.
Zurück zum Zitat Soreide K, Guest RV, Harrison EM, Kendall TJ, Garden OJ, Wigmore SJ. Systematic review of management of incidental gallbladder cancer after cholecystectomy. Br J Surg. 2019;106(1):32–45.CrossRef Soreide K, Guest RV, Harrison EM, Kendall TJ, Garden OJ, Wigmore SJ. Systematic review of management of incidental gallbladder cancer after cholecystectomy. Br J Surg. 2019;106(1):32–45.CrossRef
3.
Zurück zum Zitat Erdem S, White RR. Incidental gallbladder cancer: permission to operate. Ann Surg Oncol. 2020;27(4):980–2.CrossRef Erdem S, White RR. Incidental gallbladder cancer: permission to operate. Ann Surg Oncol. 2020;27(4):980–2.CrossRef
4.
Zurück zum Zitat Zhu AXPT, Kooby DA, et al. Gallbladder. In: Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, Sullivan DC, Jessup JM, Brierley JD, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR, editors. AJCC Cancer Staging Manual. 8th ed. Chicago: Springer; 2017. p. 303.CrossRef Zhu AXPT, Kooby DA, et al. Gallbladder. In: Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, Washington MK, Gershenwald JE, Compton CC, Hess KR, Sullivan DC, Jessup JM, Brierley JD, Gaspar LE, Schilsky RL, Balch CM, Winchester DP, Asare EA, Madera M, Gress DM, Meyer LR, editors. AJCC Cancer Staging Manual. 8th ed. Chicago: Springer; 2017. p. 303.CrossRef
5.
Zurück zum Zitat Hickman L, Contreras C. Gallbladder cancer: diagnosis, surgical management, and adjuvant therapies. Surg Clin North Am. 2019;99(2):337–55.CrossRef Hickman L, Contreras C. Gallbladder cancer: diagnosis, surgical management, and adjuvant therapies. Surg Clin North Am. 2019;99(2):337–55.CrossRef
6.
Zurück zum Zitat Eriksson S, Aronsson B. Medical implications of nosocomial infection with Clostridium difficile. Scand J Infect Dis. 1989;21(6):733–4.CrossRef Eriksson S, Aronsson B. Medical implications of nosocomial infection with Clostridium difficile. Scand J Infect Dis. 1989;21(6):733–4.CrossRef
7.
Zurück zum Zitat Lundgren L, Muszynska C, Ros A, Persson G, Gimm O, Andersson B, et al. Management of incidental gallbladder cancer in a national cohort. Br J Surg. 2019;106(9):1216–27.CrossRef Lundgren L, Muszynska C, Ros A, Persson G, Gimm O, Andersson B, et al. Management of incidental gallbladder cancer in a national cohort. Br J Surg. 2019;106(9):1216–27.CrossRef
8.
Zurück zum Zitat de Aretxabala X, Oppliger F, Solano N, Rencoret G, Vivanco M, Carvajal D, et al. Laparoscopic management of incidental gallbladder cancer. Surg Endosc. 2018;32(10):4251–5.CrossRef de Aretxabala X, Oppliger F, Solano N, Rencoret G, Vivanco M, Carvajal D, et al. Laparoscopic management of incidental gallbladder cancer. Surg Endosc. 2018;32(10):4251–5.CrossRef
9.
Zurück zum Zitat Vega EA, De Aretxabala X, Qiao W, Newhook TE, Okuno M, Castillo F, et al. Comparison of oncological outcomes after open and laparoscopic re-resection of incidental gallbladder cancer. Br J Surg. 2020;107(3):289–300.CrossRef Vega EA, De Aretxabala X, Qiao W, Newhook TE, Okuno M, Castillo F, et al. Comparison of oncological outcomes after open and laparoscopic re-resection of incidental gallbladder cancer. Br J Surg. 2020;107(3):289–300.CrossRef
10.
Zurück zum Zitat Goussous N, Maqsood H, Patel K, Ferdosi H, Muhammad N, Sill AM, et al. Clues to predict incidental gallbladder cancer. Hepatobiliary Pancreat Dis Int. 2018;17(2):149–54.CrossRef Goussous N, Maqsood H, Patel K, Ferdosi H, Muhammad N, Sill AM, et al. Clues to predict incidental gallbladder cancer. Hepatobiliary Pancreat Dis Int. 2018;17(2):149–54.CrossRef
11.
Zurück zum Zitat Cherkassky L, Jarnagin W. Selecting treatment sequence for patients with incidental gallbladder cancer: a neoadjuvant approach versus upfront surgery. Updates Surg. 2019;71(2):217–25.CrossRef Cherkassky L, Jarnagin W. Selecting treatment sequence for patients with incidental gallbladder cancer: a neoadjuvant approach versus upfront surgery. Updates Surg. 2019;71(2):217–25.CrossRef
12.
Zurück zum Zitat Strobel O, Buchler MW. Management and prognosis of incidental gallbladder cancer after cholecystectomy. Chirurg. 2020;91(3):262.CrossRef Strobel O, Buchler MW. Management and prognosis of incidental gallbladder cancer after cholecystectomy. Chirurg. 2020;91(3):262.CrossRef
13.
Zurück zum Zitat Kim JH, Lee JY, Baek JH, Eun HW, Kim YJ, Han JK, et al. High-resolution sonography for distinguishing neoplastic gallbladder polyps and staging gallbladder cancer. AJR Am J Roentgenol. 2015;204(2):W150–W9.CrossRef Kim JH, Lee JY, Baek JH, Eun HW, Kim YJ, Han JK, et al. High-resolution sonography for distinguishing neoplastic gallbladder polyps and staging gallbladder cancer. AJR Am J Roentgenol. 2015;204(2):W150–W9.CrossRef
14.
Zurück zum Zitat DesJardins H, Duy L, Scheirey C, Schnelldorfer T. Porcelain gallbladder: is observation a safe option in select populations? J Am Coll Surg. 2018;226(6):1064–9.CrossRef DesJardins H, Duy L, Scheirey C, Schnelldorfer T. Porcelain gallbladder: is observation a safe option in select populations? J Am Coll Surg. 2018;226(6):1064–9.CrossRef
15.
Zurück zum Zitat Tamandl D, Ba-Ssalamah A, Bohm G, Emmanuel K, Forstner R, Fugger R, et al. Austrian consensus guidelines on imaging requirements prior to hepatic surgery and during follow-up in patients with malignant hepatic lesions. Wien Klin Wochenschr. 2018;130(21–22):665–72.CrossRef Tamandl D, Ba-Ssalamah A, Bohm G, Emmanuel K, Forstner R, Fugger R, et al. Austrian consensus guidelines on imaging requirements prior to hepatic surgery and during follow-up in patients with malignant hepatic lesions. Wien Klin Wochenschr. 2018;130(21–22):665–72.CrossRef
16.
Zurück zum Zitat Toren W, Ansari D, Soreide K, Andersson R. Re-resection for incidentally detected gallbladder cancer: weighing in on the options. Eur J Surg Oncol. 2020;46(4 Pt A):495–7.CrossRef Toren W, Ansari D, Soreide K, Andersson R. Re-resection for incidentally detected gallbladder cancer: weighing in on the options. Eur J Surg Oncol. 2020;46(4 Pt A):495–7.CrossRef
17.
Zurück zum Zitat Vega EA, Vinuela E, Okuno M, Joechle K, Sanhueza M, Diaz C, et al. Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors. HPB. 2019;21(8):1046–56.CrossRef Vega EA, Vinuela E, Okuno M, Joechle K, Sanhueza M, Diaz C, et al. Incidental versus non-incidental gallbladder cancer: index cholecystectomy before oncologic re-resection negatively impacts survival in T2b tumors. HPB. 2019;21(8):1046–56.CrossRef
18.
Zurück zum Zitat Wiles R, Thoeni RF, Barbu ST, Vashist YK, Rafaelsen SR, Dewhurst C, et al. Management and follow-up of gallbladder polyps : joint guidelines between the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery—European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE). Eur Radiol. 2017;27(9):3856–66.CrossRef Wiles R, Thoeni RF, Barbu ST, Vashist YK, Rafaelsen SR, Dewhurst C, et al. Management and follow-up of gallbladder polyps : joint guidelines between the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery—European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE). Eur Radiol. 2017;27(9):3856–66.CrossRef
19.
Zurück zum Zitat Goetze TO, Bechstein WO, Bankstahl US, Keck T, Konigsrainer A, Lang SA, et al. Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC)—a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)—the AIO/ CALGP/ ACO- GAIN-trial. BMC Cancer. 2020;20(1):122.CrossRef Goetze TO, Bechstein WO, Bankstahl US, Keck T, Konigsrainer A, Lang SA, et al. Neoadjuvant chemotherapy with gemcitabine plus cisplatin followed by radical liver resection versus immediate radical liver resection alone with or without adjuvant chemotherapy in incidentally detected gallbladder carcinoma after simple cholecystectomy or in front of radical resection of BTC (ICC/ECC)—a phase III study of the German registry of incidental gallbladder carcinoma platform (GR)—the AIO/ CALGP/ ACO- GAIN-trial. BMC Cancer. 2020;20(1):122.CrossRef
20.
Zurück zum Zitat Ustaalioglu OBB, Bilici A, Seker M, Kefeli U, Aydin D, Celik S, et al. Prognostic factors for operated gallbladder cancer. J Gastrointest Cancer. 2019;50(3):451–7.CrossRef Ustaalioglu OBB, Bilici A, Seker M, Kefeli U, Aydin D, Celik S, et al. Prognostic factors for operated gallbladder cancer. J Gastrointest Cancer. 2019;50(3):451–7.CrossRef
21.
Zurück zum Zitat de Savornin Lohman EAJ, van der Geest LG, de Bitter TJJ, Nagtegaal ID, van Laarhoven C, van den Boezem P, et al. Re-resection in incidental gallbladder cancer: survival and the incidence of residual disease. Ann Surg Oncol. 2020;27(4):1132–42.CrossRef de Savornin Lohman EAJ, van der Geest LG, de Bitter TJJ, Nagtegaal ID, van Laarhoven C, van den Boezem P, et al. Re-resection in incidental gallbladder cancer: survival and the incidence of residual disease. Ann Surg Oncol. 2020;27(4):1132–42.CrossRef
22.
Zurück zum Zitat Aloia TA, Jarufe N, Javle M, Maithel SK, Roa JC, Adsay V, et al. Gallbladder cancer: expert consensus statement. HPB. 2015;17(8):681–90.CrossRef Aloia TA, Jarufe N, Javle M, Maithel SK, Roa JC, Adsay V, et al. Gallbladder cancer: expert consensus statement. HPB. 2015;17(8):681–90.CrossRef
23.
Zurück zum Zitat Kim BH, Kim SH, Song IS, Chun GS. The appropriate surgical strategy for T1b gallbladder cancer incidentally diagnosed after a simple cholecystectomy. Ann Hepatobiliary Pancreat Surg. 2019;23(4):327–33.CrossRef Kim BH, Kim SH, Song IS, Chun GS. The appropriate surgical strategy for T1b gallbladder cancer incidentally diagnosed after a simple cholecystectomy. Ann Hepatobiliary Pancreat Surg. 2019;23(4):327–33.CrossRef
24.
Zurück zum Zitat Lee H, Choi DW, Park JY, Youn S, Kwon W, Heo JS, et al. Surgical strategy for T2 gallbladder cancer according to tumor location. Ann Surg Oncol. 2015;22(8):2779–86.CrossRef Lee H, Choi DW, Park JY, Youn S, Kwon W, Heo JS, et al. Surgical strategy for T2 gallbladder cancer according to tumor location. Ann Surg Oncol. 2015;22(8):2779–86.CrossRef
Metadaten
Titel
Management of early-stage gallbladder cancer
verfasst von
Doris Wagner, MD
Georg Werkgartner
Klaus Kaczirek
Publikationsdatum
07.05.2021
Verlag
Springer Vienna
Erschienen in
European Surgery / Ausgabe 3/2021
Print ISSN: 1682-8631
Elektronische ISSN: 1682-4016
DOI
https://doi.org/10.1007/s10353-021-00718-8

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