Acute retinal necrosis (ARN) in the context of neonatal HSV-2 exposure and subconjunctival dexamethasone: case report and literature review
Main Article Content
Abstract
HSV-2 is an important cause of the acute retinal necrosis (ARN) syndrome in younger patients. We describe an atypical case of HSV-2 ARN in the context of neonatal exposure and subconjunctival steroid injection. Clinicians should be aware of the association of neonatal or congenital exposure to HSV-2 as a risk factor for this disease because early treatment may improve outcome and/or avoid involvement of both eyes.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
Muthiah MN, Michaelides M, Child CS, Mitchell SM. Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK. Br J Ophthalmol 2007; 91: 1452-5.
Holland GN. Standard diagnostic criteria for the acute retinal necrosis syndrome. Executive Committee of the American Uveitis Society. Am J Ophthalmol 1994;117:663-7.
Van Gelder RN, Willig J, Holland G, Kaplan H. Herpes simplex virus type 2 as a cause of acute retinal necrosis syndrome in young patients. Ophthalmology 2001;108:869-76.
Lau CH, Missotten T, Salzmann J, Lightman SL. Acute retinal necrosis: features, management, and outcomes. Ophthalmology 2007;14:756-62.
Thompson WS, Culbertson WW, Smiddy WE, Robertson JE, Robsenbaum JT. Acute retinal necrosis caused by reactivation of herpes simplex virus type 2. Am J Ophthalmol 1994;118:205-11.
Landry ML, Mullangi P, Nee P, Klein BR. Herpes simplex virus type 2 acute retinal necrosis 9 years after neonatal herpes. J Pediatr 2005;146:836-8.
Culbertson WW, Atherton SS. Acute retinal necrosis and similar retinitis syndromes. Int Ophthalmol Clin 1993; 33:129-43.
Toh T, Borthwick JH. Acute Retinal Necrosis post intravitreal injection of triamcinolone acetonide. Clin Experiment Ophthalmol 2006;34:380-2.
el Azazi M, Samuelsson A, Linde A, Forsgren M, Intrathecal antibody production against viruses of the herpesvirus family in acute retinal necrosis syndrome. Am J Ophthalmol 1991;112:76-82.
Schlingemann RO, Bruinenberg M, Wertheim-van Dillen P, Feron E, Twenty years’ delay of fellow eye involvement in herpes simplex virus type 2-associated bilateral acute retinal necrosis syndrome. Am J Ophthalmol 1996;122:891-2.
Pavesio CE, Conrad DK, McCluskey PJ, et al. Delayed acute retinal necrosis after herpetic encephalitis. Br J Ophthalmol 1997;81:415-6.
Levinson R, Reidy R, Chiu M, Acute retinal necrosis after neonatal herpes encephalitis. Br J Ophthalmol 1999;83:123-4.
Itoh N, Matsumara N, Ogi A, et al. High prevalence of herpes simplex virus type 2 in acute retinal necrosis syndrome associated with herpes simplex virus in Japan. Am J Ophthalmol 2000;129:404-5.
Ganatra J, Chandler D, Santos C, Kuppermann B, Margolis T. Viral causes of the acute retinal necrosis syndrome. Am J Ophthalmol 2000;129:166-72.
Tan JCH, Byles D, Stanford MR, Frith PA, Graham EM. Acute retinal necrosis in children caused by herpes simplex virus. Retina 2001;21:344-7.
Markomichelakis NN, Zafirakis P, Karambogia-Karefillidi P, et al. Herpes simplex virus type 2: a cause of acute retinal necrosis syndrome. Ocul Immunol Inflamm 2001;9:103-9.
Kychenthal A, Coombes A, Greenwood J, Pavesio C, Aylward GW, Bilateral acute retinal necrosis and herpes simplex type 2 encephalitis in a neonate, Br J Ophthalmol 2001;85:629-30.
Tran THC, Rozenberg F, Cassoux N, Rao NA, LeHoang P, Bodaghi B. Polymerase chain reaction analysis of aqueous humour samples in necrotising retinitis. Br J Ophthalmol 2003;87:79-83.
King J, Chung M, DiLoreto D. A 9-year-old girl with herpes simplex virus type 2 acute retinal necrosis treated with intravitreal foscarnet. Ocul Immunol Inflamm 2007;15:395-8.
Tanaka-Kitajima N, Iwata N, Ando Y, et al. Acute retinal necrosis caused by herpes simplex virus type 2 in a 3-year-old Japanese boy. Eur J Pediatr 2009;168:1125-8.
Grose C. Acute retinal necrosis caused by herpes simplex virus type 2 in children: reactivation of an undiagnosed latent neonatal herpes infection. Semin Pediatr Neurol 2012;19:115-8.
Tibbets MD, Shah CP, Young LH, Duker JS, Maguire JI, Morley MG. Treatment of acute retinal necrosis. Ophthalmology 2010;117: 818-24.
Sims J, Yeoh J, Stawell RJ. Acute retinal necrosis: a case series with clinical features and treatment outcomes. Clin Experiment Ophthalmol 2009; 37:473-77.