RESEARCH PAPER
Association between insulin therapy and quality of life in diabetes
 
More details
Hide details
1
Uniwersytet Rzeszowski; Wydział Medyczny, Poland
 
2
Podkarpacki Szpital Wojewódzki im. Jana Pawła II w Krośnie, Poland
 
3
Szpital Miejski w Przemyślu, Poland
 
 
Corresponding author
Mariusz Dąbrowski   

Uniwersytet Rzeszowski; Wydział Medyczny, Poland
 
 
J Pre Clin Clin Res. 2017;11(1):10-14
 
KEYWORDS
ABSTRACT
Introduction:
Diabetes is associated with a lower quality of life (QoL). Insulin therapy is perceived as an additional factor affecting QoL. The objective of this study, using standardized tools, was to evaluate to what extent insulin treatment has an effect on QoL in diabetes.

Material and Methods:
60 diabetic patients treated with insulin and 90 with oral drugs, all aged over 30, were included into the study. To assess the QoL of patients, SF-36 v.2 and WHOQOL-BREF questionnaires were used. In addition, demographic data were collected.

Results:
Insulin treated patients had a significantly lower Mental Component Score in SF-36 v.2 questionnaire. No significant differences between the two groups were found in the components of physical domain of SF-36 v.2 and in four domains of WHOQOL-BREF questionnaires. Insulin therapy was significantly associated with lower educational level. The strongest association with QoL in both questionnaires was found for professional activity and age.

Conclusions:
The results of this study indicate the need for psychological support for patients with diabetes treated with insulin to improve their mental coping. Diabetic patients should also be advised to continue their professional activity for as long as possible due to its important role in maintaining QoL.

 
REFERENCES (25)
1.
International Diabetes Federation. IDF Diabetes Atlas. Sixth edition. 2014 Update. Available at: http://www.idf.org/diabetesatl.... Accessed 13th August 2015.
 
2.
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004; 27(5): 1047–1053.
 
3.
Schram MT, Baan CA, Pouwer F. Depression and quality of life in patients with diabetes: a systematic review from the European depression in diabetes (EDID) research consortium. Curr Diabetes Rev. 2009; 5(2): 112–119.
 
4.
Norris SL, McNally TK, Zhang X et al. Published norms underestimate the health-related quality of life among persons with type 2 diabetes. J ClinEpidemiol. 2011; 64(4): 358–365.
 
5.
Rubin RR, Peyrot M. Quality of life and diabetes. Diabetes Metab Res Rev. 1999; 15: 205–218.
 
6.
Pouwer F, Hermanns N. Insulin therapy and quality of life. A review. Diabetes Metab Res Rev. 2009; 25(Suppl 1): S4–S10.
 
7.
de Grauw WJ, van de Lisdonk EH, Behr RR, van Gerven WHEM, van den Hoogen HJM, van Weel C. The impact of type 2 diabetes mellitus on daily functioning. Fam Pract. 1999; 16: 133–139.
 
8.
. Hörnquist JO, Wikby A, Stenström U, Andersson PO, Akerlind I. Type II diabetes and quality of life: a review of the literature. Pharmacoeconomics. 1995; 8(Suppl 1): 12–16.
 
9.
Kemmer FW, Berger M. Therapy and better quality of life: the dichotomous role of exercise in diabetes mellitus. Diabetes Metab Rev. 1986; 2(1–2): 53–68.
 
10.
Eiser C, Tooke JE. Quality of life in type II diabetes: evaluation and applications. Pharmacoeconomics. 1995; 8(Suppl 1): 17–22.
 
11.
Speight J, Reaney MD, Barnard KD. Not all roads lead to Rome – a review of quality of life measurement in adults with diabetes. Diabet Med. 2009; 26(4): 315–327.
 
12.
Dudzińska M, Tarach JS, Nowakowski A. Pomiar jakości życia zależnej od zdrowia w cukrzycy (Measurement of health-relatedquality of life in diabetesmellitus). Diabet Prakt. 2011; 12(2): 56–64 (in Polish).
 
13.
Levterova BA, Dimitrova DD, Levterov GE, Dragova EA. Instruments for disease-specific quality-of-life measurement in patients with type 2 diabetes mellitus – a systematic review. Folia Med (Plovdiv) 2013; 55(1): 83–92.
 
14.
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes, 2015: A patient-centered approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2015; 38: 140–149.
 
15.
UKPDS Group. Quality of life in type 2 diabetic patients is affected by complications but not by intensive policies to improve blood glucose or blood pressure control (UKPDS 37). Diabetes Care 1999; 22: 1125–1136.
 
16.
Quah JH, Luo N, Ng WY, How CH, Tay EG. Health-related quality of life is associated with diabetic complications, but not with short-term diabetic control in primary care. Ann Acad Med Singapore. 2011; 40(6): 276–286.
 
17.
Barendse S, Singh H, Frier BM, Speight J. The impact of hypoglycaemia on quality of life and related patient-reported outcomes in Type 2 diabetes: a narrative review. Diabet Med. 2012; 29(3): 293–302.
 
18.
Fal AM, Jankowska B, Uchmanowicz I, Sen M, Panaszek B, Polanski J. Type 2 diabetes quality of life patients treated with insulin and oral hypoglycemic medication. Acta Diabetol. 2011; 48(3): 237–242.
 
19.
Pufal J, Gierach M, Pufal M, Bronisz A, Kiełbasa L, Junik R. Wpływ czynników społeczno-demograficznych i klinicznych na jakość życia chorych na cukrzycę typu 2 (The influence of socio-demographic and clinicalfactors on qualityof life of patients with type 2 diabetes). Diabetologia Dosw Klin 2004; 4(2): 137–143 (in Polish).
 
20.
Shah S, Zilov A, Malek R, Soewondo P, Bech O, Litwak L. Improvements in quality of life associated with insulin analogue therapies in people with type 2 diabetes: results from the A1chieve observational study. Diabetes Res Clin Pract. 2011; 94(3): 364–370.
 
21.
Yang W, Zhuang X, Li Y, Wang Q, Bian R, Shen J, Hammerby E, Yang L. Improvements in quality of life associated with biphasic insulin aspart 30 in type 2 diabetes patients in China: results from the A1chieve® observational study. Health Qual Life Outcomes. 2014;12: 137. doi: 10.1186/s12955-014-0137-9.
 
22.
Hajos TR, Pouwer F, de Grooth R, et al.Initiation of insulin glargine in patients with Type 2 diabetes in suboptimal glycaemic control positively impacts health-related quality of life. A prospective cohort study in primary care. Diabet Med. 2011; 28(9): 1096–1102.
 
23.
Hermanns N, Kulzer B, Kohlmann T, et al. Treatment satisfaction and quality-of-life between type 2 diabetes patients initiating long- vs. intermediate-acting basal insulin therapy in combination with oral hypoglycemic agents – a randomized, prospective, crossover, open clinical trial. Health Qual Life Outcomes. 2015 Jun 9; 13: 77. doi: 10.1186/s12955-015-0279-4.
 
24.
Braun A, Sämann A, Kubiak T, et al. Effects of metabolic control, patient education and initiation of insulin therapy on the quality of life of patients with type 2 diabetes mellitus. Patient Educ Couns. 2008; 73(1): 50–59.
 
25.
Bourdel-Marchasson I, Druet C, Helmer C, et al. Correlates of health-related quality of life in French people with type 2 diabetes. Diabetes Res Clin Pract. 2013; 101(2): 226–235.
 
eISSN:1898-7516
ISSN:1898-2395
Journals System - logo
Scroll to top