First Case Report of the Antemortem Diagnosis of Nonbacterial Thrombotic Endocarditis of a Mechanical Prosthetic Valve

Hideki Yasutake; Yasuo Sugano; Yoshihiko Ikeda; Takahiro Ohara; Takuya Hasegawa; Hideaki Kanzaki; Toshihisa Anzai

doi:10.2169/internalmedicine.55.5470

CASE REPORTS

First Case Report of the Antemortem Diagnosis of Nonbacterial Thrombotic Endocarditis of a Mechanical Prosthetic Valve

Hideki Yasutake, Yasuo Sugano, Yoshihiko Ikeda, Takahiro Ohara, Takuya Hasegawa, Hideaki Kanzaki, Toshihisa Anzai

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Keywords: nonbacterial thrombotic endocarditis, prosthetic valve, malignancy, diagnosis

JOURNAL OPEN ACCESS

2016 Volume 55 Issue 3 Pages 255-257

DOI https://doi.org/10.2169/internalmedicine.55.5470

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Abstract

A 67-year-old man with a history of aortic mechanical valve replacement exhibited an abnormal mass on the sewing ring of the prosthesis on echocardiography. Despite receiving strong anticoagulation, he developed acute cerebral infarction due to the formation of emboli resulting from the thrombus and underwent urgent re-aortic valve replacement. Based on the microscopic findings of the resected mass, he was finally diagnosed as having nonbacterial thrombotic endocarditis (NBTE) of the mechanical prosthetic valve, which was thought to be associated with colorectal cancer. We herein report the first known case of an antemortem diagnosis of NBTE on a mechanical heart valve.

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