Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Acute Disseminated Encephalomyelitis Associated with Oral Polio Vaccine
Kensaku ShibazakiTatsufumi MurakamiRyutaro KushidaKatsumi KurokawaKihei TeradaYoshihide Sunada
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JOURNAL OPEN ACCESS

2006 Volume 45 Issue 20 Pages 1143-1146

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Abstract

Abstract: A 27-year-old woman presented with acute paresis after taking an oral polio vaccine (OPV). Deep tendon reflexes were preserved, needle electromyography showed no neurogenic changes, and there were no lesions on spine magnetic resonance imaging (MRI), suggesting that motor neurons of the spinal cord were not affected. Brain MRI showed abnormal lesions in the tegmentum of the upper pons, left cerebral peduncles, truncus of the corpus callosum, and right parietal lobe. Cerebrospinal fluid revealed mild pleocytosis. The most probable diagnosis was acute disseminated encephalomyelitis associated with OPV.

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© 2006 by The Japanese Society of Internal Medicine
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