Secular changes in the body dimensions of newborns from three different geographical localities are compared. Anthropometrical data of infants born in 1987 and in 2002 as a result of singleton full-term non-pathological postpartum were collected from medical records of children's out-patient clinics in three geographical localities: two big cities—Moscow and Saratov—and the town of Khvalynsk (Saratov region). The total number of newborns used in the analysis was 1,174. Body length and weight at birth from 1987 to 2002 increased in Moscow and Saratov, while in Khvalynsk there was a significant decrease of body length for boys. There is also a trend towards decrease of body weight in Khvalynsk boys and girls. It may be assumed that the changes in body sizes of newborns may be connected with socio-economic changes.