Cent Eur J Public Health 2019, 27(Supplement):S15-S28 | DOI: 10.21101/cejph.a5728

Alcohol use and its consequences in the Czech Republic

Viktor Mravčík1,2,3, Pavla Chomynová1,2,3, Blanka Nechanská1,3,4, Tereza Černíková1,2, Ladislav Csémy3,5
1 Department of Addictology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
2 National Monitoring Centre for Drugs and Addiction, Office of the Government, Prague, Czech Republic
3 Centre for Epidemiological and Clinical Research on Addictions, National Institute of Mental Health, Klecany, Czech Republic
4 Institute of Health Information and Statistics of the Czech Republic, Prague, Czech Republic
5 National Institute of Public Health, Prague, Czech Republic

Objective: Alcohol consumption is associated with substantial public health burden. This article summarises available information on the patterns and prevalence of alcohol use in the Czech Republic with a focus on the heavy alcohol use and its health and social consequences.

Methods: A non-systematic literature review was conducted. The data sources included primarily 3 series of surveys in the adult population, 2 series of surveys in the school population, routine monitoring system of per capita alcohol consumption, routine statistics on alcohol-related morbidity and mortality, and alcohol-related crime.

Results: In recent years the registered alcohol consumption in the Czech Republic has been very high; 9.8 litres of pure alcohol were consumed per capita in 2017. Recently, the prevalence of hazardous alcohol consumption in the adult population has reached 16.8-17.6% and harmful alcohol consumption 9.0-9.3%. From 12% to 17% of adult population and 12% of adolescent population were heavy episodic drinkers. Alcohol-related disorders are disproportionately higher (2-3 times) among men. Mortality for alcohol-related causes fully attributable to alcohol (AAF = 100%) and their proportion in overall mortality is on increase.

Conclusions: Alcohol consumption as well as the prevalence of heavy episodic drinking in the Czech Republic belongs among the highest globally. On the other hand, declines in alcohol use have been recently observed among children and adolescents. Available data on alcohol-related morbidity indicate stable situation, though alcohol-related mortality is increasing. Alcohol-related burden is rather underestimated and evidence-based alcohol policy should be increasingly implemented.

Keywords: alcohol, heavy alcohol use, alcohol-related harm

Received: March 1, 2019; Revised: July 10, 2019; Accepted: July 10, 2019; Published: December 31, 2019  Show citation

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Mravčík V, Chomynová P, Nechanská B, Černíková T, Csémy L. Alcohol use and its consequences in the Czech Republic. Cent Eur J Public Health. 2019;27(Supplement):S15-28. doi: 10.21101/cejph.a5728. PubMed PMID: 31901189.
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    References

    1. GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1345-422. Go to original source... Go to PubMed...
    2. World Health Organization. Global status report on alcohol and health 2018. Geneva: WHO; 2018.
    3. GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018;392(10152):1015-35. Go to original source... Go to PubMed...
    4. Zima T. Alcohol Abuse. EJIFCC. 2018;29(4):285-9.
    5. Rehm J. The risks associated with alcohol use and alcoholism. Alcohol Res Health. 2011;34(2):135-43.
    6. World Health Organisation. Global alcohol-attributable fractions for deaths, DALYs and YLDs by disease/injury 2012 [Internet]. Geneva: WHO [cited 2019 Jun 2.]. Available from: https://www.who.int/substance_abuse/facts/alcohol_attributable_fractions_global/en/.
    7. Praud D, Rota M, Rehm J, Shield K, Zatonski W, Hashibe M, et al. Cancer incidence and mortality attributable to alcohol consumption. Int J Cancer. 2016;138(6):1380-7. Go to original source... Go to PubMed...
    8. Rehm J, Shield KD, Roerecke M, Gmel G. Modelling the impact of alcohol consumption on cardiovascular disease mortality for comparative risk assessments: an overview. BMC Public Health. 2016;16:363. doi: 10.1186/s12889-016-3026-9. Go to original source... Go to PubMed...
    9. Room R. Concepts and items in measuring social harm from drinking. J Subst Abuse. 2000;12(1-2):93-111. Go to original source... Go to PubMed...
    10. Gmel G, Rehm J. Harmful alcohol use. Alcohol Res Health. 2003;27(1):52-62.
    11. Edman J. Harm to others - Rediscovered or Eternal? Nordic Studies on Alcohol and Drugs. 2016;33(5-6):479-81. Go to original source...
    12. Room R, Laslett A-M, Jiang H. Conceptual and methodological issues in studying alcohol's harm to others. Nordic Studies on Alcohol and Drugs. 2016;33(5-6):455-78. Go to original source...
    13. Sampson PD, Streissguth AP, Bookstein FL, Barr HM. On categorizations in analyses of alcohol teratogenesis. Environ Health Perspect. 2000;108 Suppl 3:421-8. Go to original source... Go to PubMed...
    14. Vorgias D, Bernstein B. Fetal Alcohol Syndrome. In: StatPearls [Internet]. Treasure Island: StatPearls Publishing LLC.; 2018 [cited 2019 Jul 10]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK448178/.
    15. Rehm J, Marmet S, Anderson P, Gual A, Kraus L, Nutt DJ, et al. Defining substance use disorders: do we really need more than heavy use? Alcohol Alcohol. 2013;48(6):633-40. Go to original source... Go to PubMed...
    16. Jayasekara H, English DR, Room R, MacInnis RJ. Alcohol consumption over time and risk of death: a systematic review and meta-analysis. Am J Epidemiol. 2014;179(9):1049-59. Go to original source... Go to PubMed...
    17. Rehm J, Shield KD, Gmel G, Rehm MX, Frick U. Modeling the impact of alcohol dependence on mortality burden and the effect of available treatment interventions in the European Union. Eur Neuropsychopharmacol. 2013;23(2):89-97. Go to original source... Go to PubMed...
    18. Rehm J, Anderson P, Gual A, Kraus L, Marmet S, Nutt DJ, et al. The tangible common denominator of substance use disorders: a reply to commentaries to Rehm et al. (2013a). Alcohol Alcohol. 2014;49(1):118-22. Go to original source... Go to PubMed...
    19. Irving HM, Samokhvalov AV, Rehm J. Alcohol as a risk factor for pancreatitis. A systematic review and meta-analysis. JOP. 2009;10(4):387-92. Go to PubMed...
    20. Rehm J, Taylor B, Mohapatra S, Irving H, Baliunas D, Patra J, et al. Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis. Drug Alcohol Rev. 2010;29(4):437-45. Go to original source... Go to PubMed...
    21. Gallagher C, Hendriks JML, Elliott AD, Wong CX, Rangnekar G, Middeldorp ME, et al. Alcohol and incident atrial fibrillation - a systematic review and meta-analysis. Int J Cardiol. 2017;246:46-52. Go to original source... Go to PubMed...
    22. Taylor B, Irving HM, Baliunas D, Roerecke M, Patra J, Mohapatra S, et al. Alcohol and hypertension: gender differences in dose-response relationships determined through systematic review and meta-analysis. Addiction. 2009;104(12):1981-90. Go to original source... Go to PubMed...
    23. Roerecke M, Rehm J. Irregular heavy drinking occasions and risk of ischemic heart disease: a systematic review and meta-analysis. Am J Epidemiol. 2010;171(6):633-44. Go to original source... Go to PubMed...
    24. Patra J, Taylor B, Irving H, Roerecke M, Baliunas D, Mohapatra S, et al. Alcohol consumption and the risk of morbidity and mortality for different stroke types - a systematic review and meta-analysis. BMC Public Health. 2010;10:258. doi: 10.1186/1471-2458-10-258. Go to original source... Go to PubMed...
    25. Lonnroth K, Williams BG, Stadlin S, Jaramillo E, Dye C. Alcohol use as a risk factor for tuberculosis - a systematic review. BMC Public Health. 2008;8:289. doi: 10.1186/1471-2458-8-289. Go to original source... Go to PubMed...
    26. Rehm J, Samokhvalov AV, Neuman MG, Room R, Parry C, Lonnroth K, et al. The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review. BMC Public Health. 2009;9:450. doi: 10.1186/1471-2458-9-450. Go to original source... Go to PubMed...
    27. Samokhvalov AV, Irving HM, Rehm J. Alcohol consumption as a risk factor for pneumonia: a systematic review and meta-analysis. Epidemiol Infect. 2010;138(12):1789-95. Go to original source... Go to PubMed...
    28. Cherpitel CJ, Ye Y, Bond J, Borges G, Monteiro M. Relative risk of injury from acute alcohol consumption: modeling the dose-response relationship in emergency department data from 18 countries. Addiction. 2015;110(2):279-88. Go to original source... Go to PubMed...
    29. Pelucchi C, Tramacere I, Boffetta P, Negri E, La Vecchia C. Alcohol consumption and cancer risk. Nutr Cancer. 2011;63(7):983-90. Go to original source... Go to PubMed...
    30. de Menezes RF, Bergmann A, Thuler LC. Alcohol consumption and risk of cancer: a systematic literature review. Asian Pac J Cancer Prev. 2013;14(9):4965-72. Go to original source... Go to PubMed...
    31. Gmel G, Rehm J, Room R, Greenfield TK. Dimensions of alcohol-related social and health consequences in survey research. J Subst Abuse. 2000;12(1-2):113-38. Go to original source... Go to PubMed...
    32. Rehm J, Baliunas D, Borges GL, Graham K, Irving H, Kehoe T, et al. The relation between different dimensions of alcohol consumption and burden of disease: an overview. Addiction. 2010;105(5):817-43. Go to original source... Go to PubMed...
    33. Gmel G, Gutjahr E, Rehm J. How stable is the risk curve between alcohol and all-cause mortality and what factors influence the shape? A precision-weighted hierarchical meta-analysis. Eur J Epidemiol. 2003;18(7):631-42. Go to original source... Go to PubMed...
    34. Vahtera J, Poikolainen K, Kivimaki M, Ala-Mursula L, Pentti J. Alcohol intake and sickness absence: a curvilinear relation. Am J Epidemiol. 2002;156(10):969-76. Go to original source... Go to PubMed...
    35. Fehringer G, Brenner DR, Zhang ZF, Lee YA, Matsuo K, Ito H, et al. Alcohol and lung cancer risk among never smokers: A pooled analysis from the international lung cancer consortium and the SYNERGY study. Int J Cancer. 2017;140(9):1976-84. Go to original source... Go to PubMed...
    36. Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, et al. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ. 2014;349:g4164. doi: https://doi.org/10.1136/bmj.g4164. Go to original source... Go to PubMed...
    37. Chikritzhs T, Stockwell T, Naimi T, Andreasson S, Dangardt F, Liang W. Has the leaning tower of presumed health benefits from 'moderate' alcohol use finally collapsed? Addiction. 2015;110(5):726-7. Go to original source... Go to PubMed...
    38. Stockwell T, Zhao J, Panwar S, Roemer A, Naimi T, Chikritzhs T. Do "moderate" drinkers have reduced mortality risk? A systematic review and meta-analysis of alcohol consumption and all-cause mortality. J Stud Alcohol Drugs. 2016;77(2):185-98. Go to original source... Go to PubMed...
    39. Patra J, Taylor B, Rehm J. Deaths associated with high-volume drinking of alcohol among adults in Canada in 2002: a need for primary care intervention? Contemp Drug Probl. 2009;36(1-2):283-301. Go to original source...
    40. Toma A, Pare G, Leong DP. Alcohol and cardiovascular disease: how much is too much? Curr Atheroscler Rep. 2017;19(3):13. doi: https://doi.org/10.1007/s11883-017-0647-0. Go to original source... Go to PubMed...
    41. Moskalewicz J, Sieroslawski J. Drinking Population surveys - guidance document for standardized approach. Final report for the Project Standardizing Measurement of Alcohol-Related Troubles - SMART. Warsaw: Institute of Psychiatry and Neurology; 2010.
    42. Laslett AM, Room R, Ferris J, Wilkinson C, Livingston M, Mugavin J. Surveying the range and magnitude of alcohol's harm to others in Australia. Addiction. 2011;106(9):1603-11. Go to original source... Go to PubMed...
    43. Ruprich J. Overview of national guidelines for moderate consumption of alcoholic beverages. Prague: NIPH; 2016. (In Czech.)
    44. Miovský M. Positive effects of moderate alcohol use on human health: the futile search for a third side of the coin. Adiktologie. 2017;17(2):148-60.
    45. World Health Organisation. International statistical classification of diseases and related health problems. Geneva: WHO; 2011.
    46. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association; 2013. Go to original source...
    47. Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG. AUDIT: the alcohol use disorders identification test. Guidelines for use in primary care. Geneva: WHO; 2001.
    48. Mayfield D, McLeod G, Hall P. The CAGE questionnaire: Validation of a new alcoholism instrument. Am J Psychiatry. 1974(131):1121-3. Go to original source...
    49. Cherpitel CJ, Ye Y, Bond J, Borges G, Cremonte M, Marais S, et al. Cross-national performance of the RAPS4/RAPS4-QF for tolerance and heavy drinking: data from 13 countries. J Stud Alcohol. 2005;66(3):428-32. Go to original source... Go to PubMed...
    50. Ustun B, Compton W, Mager D, Babor T, Baiyewu O, Chatterji S, et al. WHO Study on the reliability and validity of the alcohol and drug use disorder instruments: overview of methods and results. Drug Alcohol Depend. 1997;47(3):161-9. Go to original source... Go to PubMed...
    51. Lachner G, Wittchen HU, Perkonigg A, Holly A, Schuster P, Wunderlich U, et al. Structure, content and reliability of the Munich-Composite International Diagnostic Interview (M-CIDI) substance use sections. Eur Addict Res. 1998;4(1-2):28-41. Go to original source... Go to PubMed...
    52. Bloomfield K, Hope A, Kraus L. Alcohol survey measures for Europe: a literature review. Drugs (Abingdon Engl). 2013;20(5):348-60. Go to original source...
    53. Ewing JA. Detecting Alcoholism. The CAGE Questionnaire. JAMA. 1984(252):1905-7. Go to original source...
    54. Gabrhelik R, Nechanska B, Mravcik V, Skurtveit S, Lund IO, Handal M. A unique opportunity to study short and long term consequences in children prenatally exposed to illicit drugs and opioid maintenance treatment using Czech and Scandinavian registers. Cent Eur J Public Health. 2016;24(3):248-51. Go to original source... Go to PubMed...
    55. Czech Statistical Office. Consumption of alcoholic beverages per capita in the Czech Republic. Prague: CZSO; 2019 [cited 2019 Apr 1]. Available from: https://www.czso.cz/csu/czso/cr_od_roku_1989_alkohol. (In Czech.)
    56. Váňová A, Skývová M, Csémy L. Tobacco and alcohol use in the Czech Republic 2016. Prague: NIPH; 2017. (In Czech.)
    57. Chomynová P, Mravčík V. National survey on substance use 2016. Zaostřeno. 2018;16(2):1-20. (In Czech.)
    58. Chomynová P. National survey on substance use 2012. Smoking, alcohol and other drugs use in the general population. Zaostřeno na drogy. 2013;11(2):1-16. (In Czech.)
    59. Běláčková V, Nechanská B, Chomynová P, Horáková M. General population survey on drug use and attitudes towards drug use 2008. Prague: Office of the Government of the Czech Republic; 2012. (In Czech.)
    60. Institute of Health Information and Statistics of the Czech Republic. European Health Interview Survey in the Czech Republic EHIS 2008. Prague: IHIS CR; 2011. (In Czech.)
    61. Institute of Health Information and Statistics of the Czech Republic. European Health Interview Survey in the Czech Republic (EHIS 2008) - Basic Information. Prague: IHIS CR; 2016. (In Czech.)
    62. Daňková Š. EHIS 2014 - Basic survey results. Prague: IHIS CR; 2016. (In Czech.)
    63. Rehm J, Room R, Monteiro M, Gmel G, Graham K, Rehn N, et al. Alcohol use. In: Ezzati M, Lopez AD, Rodgers A, Murray CJL, editors. Comparative quantification of health risks: global and regional burden of diseases attributable to selected major risk factors. Geneva: WHO; 2004. p. 959-1108.
    64. Devaux M, Sassi F. Alcohol consumption and harmful drinking: trends and social disparities across OECD countries. Paris: OECD Publishing; 2015.
    65. Csémy L, Kážmér L, Dvořáková Z. Substance use among school-aged children: results of HBSC study 1994-2014. Presentation at regular meeting of Society for Addictive Diseases of Czech Medical Association JEP in Prague (2016 April 06). (In Czech.)
    66. Chomynová P, Csémy L, Mravčík V. European School Survey Project on Alcohol and Other Drugs (ESPAD) 2015. Zaostřeno. 2016;14(5):1-16. (In Czech.)
    67. Madarasová Gecková A, Dankulincová Z, Sigmundová D, Kalman M, editors. International report on health and lifestyle of children and school-aged children based on the 2014 HBSC research. Košice, Olomouc: Palacký University Olomouc; 2016. (In Czech.)
    68. Kohoutová I. Estimated impact of alcohol on mortality in the Czech Republic. Adiktologie. 2013;13(1):14-23. (In Czech.)
    69. Czech Statistical Office. Demographic Yearbook 2005-2017. Prague: CZSO; 2018. (In Czech.)
    70. Nešpor K, Csémy L. Domestic violence and alcohol. Čes a slov Psychiatr. 2005;101(3):174-5. (In Czech.)
    71. Martinková M, Slavětínský V, Vlach J. Selected problems of domestic violence in the Czech Republic. Prague: IKSP; 2014. (In Czech.)
    72. Pikálková S, Podaná Z, Buriánek J. Women as victims of partner violence. Prague: Slon; 2015. (In Czech.)
    73. Dohnal D, Hokr Miholová P, Šprincová V, Domesová S. Analysis of the occurrence and latency of domestic violence in partnership. Prague: Office of the Government of the Czech Republic; 2017. (In Czech.)
    74. Police Presidium of the Police of the Czech Republic. Statistical Surveys of Crime in 2017 (ESSK). Prague: Police Presidium of the Police of the Czech Republic; 2018. (In Czech.)
    75. Directorate of Traffic Police Service of the Police Presidium of the Czech Republic. An overview of road accidents in the Czech Republic in 2016. Prague: Directorate of Traffic Police Service of the Police Presidium of the Czech Republic; 2017. (In Czech.)
    76. Single E, Easton B, Collins D, Harwood H, Lapsley H, Maynard A, et al. International Guidelines for Estimating the Costs of Substance Abuse. Ottawa: Canadian Centre on Substance Abuse; 1996.
    77. Single E, Collins D, Easton B, Harwood H, Lapsley H, Kopp P, et al. International Guidelines for Estimating the Costs of Substance Abuse. Ottawa: Canadian Centre on Substance Abuse; 2001.
    78. Zábranský T, Běláčková V, Štefunková M, Vopravil J, Langrová M. Social costs of the use of alcohol, tobacco, and illegal drugs in the Czech Republic, 2007. Prague: Centre of Addictology, Department of Psychiatry of 1st Faculty of Medicine Charles University in Prague; 2011. (In Czech.)
    79. Gustavsson A, Svensson M, Jacobi F, Allgulander C, Alonso J, Beghi E, et al. Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol. 2011;21(10):718-79. Go to original source... Go to PubMed...
    80. Mlčoch T, Chadimová K, Doležal T. Social costs of the use of alcohol in the Czech Republic. Prague: iHETA; 2019. (In Czech.)
    81. OECD. Tackling harmful alcohol use: economics and public health policy. OECD Publishing; 2015.
    82. Fiala J, Sochor O, Klimusova H, Homolka M. Alcohol consumption in population aged 25-65 years living in the metropolis of South Moravia, Czech Republic. Cent Eur J Public Health. 2017;25(3):191-9. Go to original source... Go to PubMed...
    83. Liška J, Mravčík V. Alcohol use in Jindřichovice, a municipality in the Karlovy Vary region. Adiktologie. 2018;18(1):59-62.
    84. The ESPAD Group. ESPAD Report 2015. Results from the European School Survey Project on Alcohol and Other Drugs. Luxembourg: Publications Office of the European Union; 2016. 99 p.
    85. Inchley J, Currie D, Young T, Samdal O, Torsheim T, Augustson L, et al., editors. Growing up unequal: gender and socioeconomic differences in young people's health and well-being. Health-Behaviour in School-aged Children (HBSC) Study: international report from the 2013/2014 survey. Copenhagen: WHO Regional Office for Europe; 2016.
    86. Jurickova L, Ivanova K, Dobias M, Andrasik R, Ondra P. Manner of death of older people with regard to blood alcohol concentration. Cent Eur J Public Health. 2017;25(4):266-70. Go to original source... Go to PubMed...
    87. Roerecke M, Rehm J. Alcohol use disorders and mortality: a systematic review and meta-analysis. Addiction. 2013(108):1562-78. Go to original source... Go to PubMed...
    88. Laramee P, Leonard S, Buchanan-Hughes A, Warnakula S, Daeppen JB, Rehm J. Risk of all-cause mortality in alcohol-dependent individuals: a systematic literature review and meta-analysis. EBioMedicine. 2015;2(10):1394-404. Go to original source... Go to PubMed...
    89. Nechanská B, Drbohlavová B, Csémy L. Structure of mortality of persons hospitalised for alcohol use disorders in the Czech Republic from 1994 to 2013. Adiktologie. 2017;17(2):84-91. (In Czech.)
    90. Bellis MA, Hughes K, Nicholls J, Sheron N, Gilmore I, Jones L. The alcohol harm paradox: using a national survey to explore how alcohol may disproportionately impact health in deprived individuals. BMC Public Health. 2016;16:111. doi: 10.1186/s12889-016-2766-x. Go to original source... Go to PubMed...
    91. Lewer D, Meier P, Beard E, Boniface S, Kaner E. Unravelling the alcohol harm paradox: a population-based study of social gradients across very heavy drinking thresholds. BMC Public Health. 2016;16:599. doi: 10.1186/s12889-016-3265-9. Go to original source... Go to PubMed...
    92. Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet. 2009;373(9682):2223-33. Go to original source... Go to PubMed...
    93. Anderson P, Chisholm D, Fuhr DC. Effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol. Lancet. 2009;373(9682):2234-46. Go to original source... Go to PubMed...
    94. Rehm J, Lachenmeier DW, Room R. Why does society accept a higher risk for alcohol than for other voluntary or involuntary risks? BMC Medicine. 2014;12(1):189. doi: 10.1186/s12916-014-0189-z. Go to original source... Go to PubMed...
    95. Csémy L, Winkler P. Alcohol in the Czech Republic: trends in consumption, health consequences, and economic costs to society. Psychiatrie. 2012;16(4):210-6. (In Czech.)
    96. Hnilicova H, Nome S, Dobiasova K, Zvolsky M, Henriksen R, Tulupova E, et al. Comparison of alcohol consumption and alcohol policies in the Czech Republic and Norway. Cent Eur J Public Health. 2017;25(2):145-51. Go to original source... Go to PubMed...
    97. Hnilicová H, Dobiášová K. Alcohol as an issue of the public health in the Czech Republic: facts and context. Časopis lékařů českých. 2018;157(5):248-53. (In Czech.) Go to PubMed...
    98. Zakharov S, Pelclova D, Urban P, Navratil T, Diblik P, Kuthan P, et al. Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features. Clin Toxicol (Phila). 2014;52(10):1013-24. Go to original source... Go to PubMed...
    99. Mravčík V, Chomynová P, Grohmannová K, Janíková B, Tion Leštinová Z, Rous Z, et al. Annual report on drug situation in Czech Republic in 2016. Prague: Office of the Government of the Czech Republic; 2017. (In Czech.)
    100. Lange S, Probst C, Gmel G, Rehm J, Burd L, Popova S. Global prevalence of fetal alcohol spectrum disorder among children and youth: a systematic review and meta-analysis. JAMA Pediatr. 2017;171(10):948-56. Go to original source... Go to PubMed...

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