Chest
Selected ReportsPleural Effusion in Multiple Myeloma
Section snippets
Case Report
A 51-year-old man was an alcohol abuser (more than 100 g of alcohol per day) and heavy smoker (2 packs per day). One week before hospital admission, he presented with dyspnea and right-lower chest pain aggravated by coughing and breathing. Physical examination showed only decreased breath sounds in the right base. Laboratory results revealed the following: urea 64 mg/dl (10.6 mmol/L); creatinine, 1.34 mg/dl (118 νm?l/L); serum proteins, 8.9 g/dl (89 g/L); calcium, 12 mg/dl (3 mmol/L); and uric
Discussion
Pleural effusions in MM occur in about 6 percent of patients1 and are due to several etiologies requiring different types of therapy. These etiologies are, most commonly, heart failure secondary to amyloidosis, followed by the following: pulmonary embolism; chronic renal failure; second neoplasm; and pleural myelomatous involvement1, 5, 6 (from adjacent skeletal or parenchymal tumors, direct implantation of tumor nodules on the pleura, and mediastinal lymph node infiltration with lymphatic
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Cited by (97)
Massive pleural effusion due to IgG-Kappa subtype multiple myeloma: A case report
2020, Respiratory Medicine Case ReportsCitation Excerpt :The first case of MPE was reported in 1994 by Rodriguez et al. [3]. They suggested a diagnostic criterion for MPE which composes of three parameters: 1) demonstration of monoclonal protein in pleural fluid electrophoresis; 2) detection of atypical plasma cell in the pleural fluid; and 3) histological confirmation with a pleural biopsy or autopsy [3]. A systemic review in characteristics of 153 patients with MPE was reported in 2018 by Riveiro et al. [4].
Clinicopathological Profile of Myelomatous Pleural Effusion: Single-center Real-world Experience and Review of Literature
2019, Clinical Lymphoma, Myeloma and LeukemiaCitation Excerpt :Of the tested patients in the series by Cho et al, 77.8% had chromosome 13 abnormalities, and 73.5% of patients had ISS-III disease.8 Three other studies have shown a predominance of MPE in IgA myeloma with an incidence of 80%, 36.4%, and 27.6%, respectively.7,17,20 The literature suggests an increased incidence of MPE in high-risk disease, as was also seen in our study (ISS I, 0%).8,17
Characteristics of patients with myelomatous pleural effusion. A systematic review
2018, Revista Clinica EspanolaPleural effusion formation in the course of myeloma
2015, Archivos de BronconeumologiaMyelomatous pleural effusion developing after autologous stem cell transplantation in a patient with multiple myeloma: A rare case
2023, Indian Journal of Pathology and Microbiology