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Thromb Haemost 2011; 106(05): 868-876
DOI: 10.1160/TH11-05-0358
Consensus Document
Schattauer GmbH

Questions and answers on the use of dabigatran and perpectives on the use of other new oral anticoagulants in patients with atrial fibrillation.

A consensus document of the Italian Federation of Thrombosis Centers (FCSA)
Vittorio Pengo
1   Clinical Cardiology, Thrombosis Centre, University of Padova, Padova, Italy
,
Luciano Crippa
2   Thrombosis Research Unit, IRCCS H S.Raffaele, Milan, Italy
,
Anna Falanga
3   Division of Immunohematology and Transfusion Medicine, Ospedali Riuniti, Bergamo, Italy
,
Guido Finazzi
4   Division of Hematology, Ospedali Riuniti, Bergamo, Italy
,
Francesco Marongiu
5   Department of Medical Sciences, University Hospital, Cagliari, Italy
,
Gualtiero Palareti
6   Department of Angiology and Blood Coagulation ″Marino Golinelli″, University Hospital, Bologna, Italy
,
Daniela Poli
7   Department of Heart and Vessels, Thrombosis Center, Careggi University Hospital, Firenze, Italy
,
Sophie Testa
8   Thrombosis Centre, District Hospital, Cremona, Italy
,
Eros Tiraferri
9   Haemostasis and Thrombosis Centre, City Hospital, Rimini, Italy
,
Alberto Tosetto
10   Department of Hematology, San Bortolo Hospital, Vicenza, Italy
,
Armando Tripodi
11   Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Cà Granda Maggiore Hospital Foundation and Università degli Studi di Milano, Milan, Italy
,
Cesare Manotti
12   Anticoagulation Service, Fidenza, Italy
› Author Affiliations
Further Information

Publication History

Received: 27 May 2011

Accepted after major revision: 19 August 2011

Publication Date:
23 November 2017 (online)

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Summary

Dabigatran and other new oral anticoagulants (OAC) represent a step forward in stroke prevention in patients with atrial fibrillation (AF). They indeed have been shown to be an alternative to vitamin K antagonists (VKAs) without the burden of laboratory control. However, these new drugs compete with an effective and well-established therapy, thus bringing about a series of questions and doubts. In this report members of the board of the Italian Federation of Thrombosis Centers (FCSA) answer some questions every clinician might be confronted with.

Keywords

Clinical trials - oral anticoagulants - heart - prevention
 

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