ArticleThe impact of antibodies on clinical outcomes in diseases treated with therapeutic protein: Lessons learned from infantile Pompe disease
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Keywords
Pompe disease
enzyme replacement therapy
crossreactive immunologic material
CRIM negative
high sustained antibody titers
high-titer CRIM-positive
low-titer CRIM-positive
therapeutic proteins
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© 2011, The Author(s), under exclusive licence to the American College of Medical Genetics and Genomics