Original CommunicationsSurgical resection of liver metastases of gastric cancer: An analysis of a 17-year experience with 22 patients*,**
Section snippets
Methods
Between 1985 and 2001, 4730 patients underwent gastrectomy for gastric adenocarcinoma at the Department of Surgery, Cancer Institute Hospital. Of these 4730 patients, 106 patients (2%) had synchronous liver metastases, and 122 patients (3%) had metachronous liver metastases develop after resection of the primary gastric cancer. Synchronous liver metastases were found with routine abdominal computed tomography before gastrectomy. Twenty-two patients (13 male and 9 females; median age, 63 years;
Results
Surgical procedures for the primary gastric cancer consisted of 12 partial gastrectomies and 10 total gastrectomies. Twelve synchronous and 10 metachronous liver metastases were identified; 1 of the patients with a synchronous liver metastasis underwent a staged hepatectomy 2 months after a gastrectomy for primary cancer. The number of metastases at the time of the first hepatectomy was 1 in 16 patients, 2 in 2 patients, 3 in 2 patients, 5 in 1 patient, and 7 in 1 patient. The maximum size of
Discussion
We found 5% of the 4730 patients who underwent gastrectomy for gastric cancer at our institution between 1985 and 2001 developed liver metastases develop synchronously or metachronously, but only 10% of them underwent hepatic resection. This small population of patients is discussed in this study. The number of liver metastases was a significant prognostic factor for survival after hepatectomy in patients with metastasis of primary gastric cancer according to a univariate and a multivariate
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Reprint requests: Junji Yamamoto, MD, Department of Surgery, Cancer Institute Hospital, 1-37-1 Kami-Ikebukuro, Toshima-ku, Tokyo 170-8455, Japan.
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0039-6060/2003/$30.00 + 0