ElectrophysiologyRecent trends in the incidence rates of and death rates from atrial fibrillation complicating initial acute myocardial infarction: A community-wide perspective*,**
Section snippets
Methods
We studied residents of the Worcester, Massachusetts, metropolitan area who were hospitalized with a primary or secondary discharge diagnosis of AMI (International Classification of Disease [ICD]-9 code 410) in all acute care general hospitals in the Worcester Standard Metropolitan Statistical Area; 1990 census records estimate a population of 437,000 during calendar years 1990, 1991, 1993, 1995, and 1997.18, 19, 20 Sixteen teaching and community hospitals were included in this study during its
Characteristics of patients with AF complicating initial AMI
The 343 patients with AMI who developed new onset AF were significantly older, more likely to be female, and more likely to have a history of hypertension compared with patients who did not develop AF (Table I).Characteristic AF (present) (n = 343) AF (absent) (n = 2253) P Age (mean, y) 73.9 66.3 <.001 Age (y) (%) <55 7.6 21.8 55-64 11.4 19.8 <.001 65-74 28 26.5 ≥75 53 31.9
Discussion
The results of this multi-hospital, community-wide study of 2596 residents of the Worcester metropolitan area hospitalized with initial AMI and without a medical history of AF suggest declines over time (1990-1997) in the incidence of new onset AF, higher hospital death rates among patients who developed AF, and encouraging improvements in the hospital survival of patients with AF from the earliest to most recent study years. Patients who developed AF during the index hospitalization had higher
Acknowledgements
We thank the cardiology, administration, and medical records departments at participating Worcester metropolitan area hospitals for making this project feasible.
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This project was supported through funding made available by the National Institutes of Health (RO1 HL35434).
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Reprint requests: Robert J. Goldberg, PhD, Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655. E-mail: [email protected].