Aktuelle Ernährungsmedizin 2007; 32: S41-S53
DOI: 10.1055/s-2006-951876
Leitlinie Parenterale Ernährung der DGEM
© Georg Thieme Verlag KG Stuttgart · New York

9 Technik und Probleme der Zugänge in der parenteralen Ernährung

K.  W.  Jauch (gemeinsamer AG-Leiter), W.  Schregel (gemeinsamer AG-Leiter), Z.  Stanga (gemeinsamer AG-Leiter), S.  C.  Bischoff, P.  Braß, W.  Hartl, S.  Mühlebach, E.  Pscheidl, P.  Thul, O.  Volk
Further Information

Publication History

Publication Date:
04 March 2008 (online)

Literatur

  • 1 Krzywda E A, Andris D A, Edmiston C E. Catheter infections: Diagnosis, etiology, treatment and prevention.  Nutr Clin Pract. 1999;  14 178
  • 2 Chung D H, Ziegler M M. Central venous catheter access.  Nutrition. 1998;  14 119-123
  • 3 Meadows N. Monitoring and complications of parenteral nutrition.  Nutrition. 1998;  14 806-808
  • 4 Lederle F A, Parenti C M, Berskow L C, Ellingson K J. The idle intravenous catheter.  Ann Intern Med. 1992;  116 737-738
  • 5 Parenti C M, Lederle F A, Impola C L, Peterson L R. Reduction of unnecessary intravenous catheter use. Internal medicine house staff participate in a successful quality improvement project.  Arch Intern Med. 1994;  154 1829-1832
  • 6 Gebauer B, Teichgräber U K, Podrabsky P, Beck A, Wagner H J. Ultraschall- und durchleuchtungs-gesteuerte Implantation peripher inserierter zentral-venöser Katheter (PICC).  Fortschr Röntgenstr. 2004;  176 386-391
  • 7 Duerksen D R, Papineau N, Siemens J, Yaffe C. Peripherally inserted central catheters for parenteral nutrition: a comparison with centrally inserted catheters.  JPEN J Parenter Enteral Nutr. 1999;  23 85-89
  • 8 Kumar M, Amin M. The peripherally inserted central venous catheter; friend or foe?.  Int J Oral Maxillofac Surg. 2004;  33 201-204
  • 9 Nessler R. Special technique for the catheterization of „central” veins (Seldinger's or indirect technique).  Prakt Anaesth. 1978;  13 99-102
  • 10 Peters J L, Armstrong R. Air embolism occurring as a complication of central venous catheterization.  Ann Surg. 1978;  187 375-378
  • 11 Stow P J, Burrows F A, Berthelsen P G, Stöber H, Durrant S TS, Rahemtulla A. et al . Central venous catheterisation.  Lancet. 1986;  328 974-975
  • 12 Belani K G, Buckley J J, Gordon J R, Castaneda W. Percutaneous cervical central venous line placement: a comparison of the internal and external jugular vein routes.  Anesth Analg. 1980;  59 40-44
  • 13 O'Grady N P, Alexander M, Dellinger E P, Gerberding J L, Heard S O, Maki D G. et al . Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention.  MMWR Recomm Rep. 2002;  51 1-29
  • 14 Polderman K H, Girbes A R. Central venous catheter use. Part 2: infectious complications.  Intensive Care Med. 2002;  28 18-28
  • 15 Raad I, Umphrey J, Khan A, Truett L J, Bodey G P. The duration of placement as a predictor of peripheral and pulmonary arterial catheter infections.  J Hosp Infect. 1993;  23 17-26
  • 16 Richet H, Hubert B, Nitemberg G, Andremont A, Buu-Hoi A, Ourbak P. et al . Prospective multicenter study of vascular-catheter-related complications and risk factors for positive central-catheter cultures in intensive care unit patients.  J Clin Microbiol. 1990;  28 2520-2525
  • 17 Fuchs P C, Gustafson M E, King J T, Goodall P T. Assessment of catheter-associated infection risk with the Hickman right atrial catheter.  Infect Control. 1984;  5 226-230
  • 18 Thomas J H, MacArthur R I, Pierce G E, Hermreck A S. Hickman-Broviac catheters. Indications and results.  Am J Surg. 1980;  140 791-796
  • 19 Snydman D R, Murray S A, Kornfeld S J, Majka J A, Ellis C A. Total parenteral nutrition-related infections. Prospective epidemiologic study using semiquantitative methods.  Am J Med. 1982;  73 695-699
  • 20 Mermel L A. Prevention of intravascular catheter-related infections.  Ann Intern Med. 2000;  132 391-402
  • 21 Bjarnason K, Field J, Weston V, Stanga Z. Venesection for blood culture: trained nurses achieve same or lower contamination rates than doctors.  Clin Nutr. 2002;  21 10
  • 22 O'Grady N P, Alexander M, Dellinger E P, Gerberding J L, Heard S O, Maki D G. et al . Guidelines for the prevention of intravascular catheter-related infections.  Am J Infect Control. 2002;  30 476-489
  • 23 Hanna H A, Raad I. Blood products: a significant risk factor for long-term catheter-related bloodstream infections in cancer patients.  Infect Control Hosp Epidemiol. 2001;  22 165-166
  • 24 Barrett B B, Andersen J W, Anderson K C. Strategies for the avoidance of bacterial contamination of blood components.  Transfusion. 1993;  33 228-233
  • 25 Timsit J F, Sebille V, Farkas J C, Misset B, Martin J B, Chevret S. et al . Effect of subcutaneous tunneling on internal jugular catheter-related sepsis in critically ill patients: a prospective randomized multicenter study.  JAMA. 1996;  276 1416-1420
  • 26 Shaffer J L, Bakker H, Bozzetti F, Ladefoged K, Leon-Sanz M, Messing B. et al . A European survey on management of catheter-related complications in home parenteral nutrition.  Clin Nutr. 1997;  16 42
  • 27 Raad I, Davis S, Becker M, Hohn D, Houston D, Umphrey J. et al . Low infection rate and long durability of nontunneled silastic catheters. A safe and cost-effective alternative for long-term venous access.  Arch Intern Med. 1993;  153 1791-1796
  • 28 Chang L, Tsai J S, Huang S J, Shih C C. Evaluation of infectious complications of the implantable venous access system in a general oncologic population.  Am J Infect Control. 2003;  31 34-39
  • 29 Raad I, Hanna H A, Awad A, Alrahwan A, Bivins C, Khan A. et al . Optimal frequency of changing intravenous administration sets: is it safe to prolong use beyond 72 hours?.  Infect Control Hosp Epidemiol. 2001;  22 136-139
  • 30 Maki D G, Botticelli J T, LeRoy M L, Thielke T S. Prospective study of replacing administration sets for intravenous therapy at 48- vs 72-hour intervals. 72 hours is safe and cost-effective.  JAMA. 1987;  258 1777-1781
  • 31 Matlow A G, Kitai I, Kirpalani H, Chapman N H, Corey M, Perlman M. et al . A randomized trial of 72- versus 24-hour intravenous tubing set changes in newborns receiving lipid therapy.  Infect Control Hosp Epidemiol. 1999;  20 487-493
  • 32 Sitges-Serra A, Linares J, Perez J L, Jaurrieta E, Lorente L. A randomized trial on the effect of tubing changes on hub contamination and catheter sepsis during parenteral nutrition.  JPEN J Parenter Enteral Nutr. 1985;  9 322-325
  • 33 Nanninga A G, Vries E G de, Willemse P H, Oosterhuis B E, Sleijfer D T, Hoekstra H J. et al . Continuous infusion of chemotherapy on an outpatient basis via a totally implanted venous access port.  Eur J Cancer. 1991;  27 147-149
  • 34 Milani A, Vernizzi S, Passoni C, Sociale O, Macciola F, Grimaldi C. et al . Huber needle in situ inpatients under continuous infusion chemotherapy: results of a study, Phase II.  Prof Inferm. 2000;  53 71-74
  • 35 Karamanoglu A, Yumuk P F, Gumus M, Ekenel M, Aliustaoglu M, Selimen D. et al . Port needles: do they need to be removed as frequently in infusional chemotherapy?.  J Infus Nurs. 2003;  26 239-242
  • 36 Mühlebach S, Fasolini F. 10 Jahre Ernährungsteam am Kantonsspital Aarau (KSA): Aufgaben, Entwicklungen, Erfahrungen.  Viszeralchirurgie. 2000;  35 69-71
  • 37 Quaglia M P La, Lucas A, Thaler H T, Friedlander-Klar H, Exelby P R, Groeger J S. A prospective analysis of vascular access device-related infections in children.  J Pediatr Surg. 1992;  27 840-842
  • 38 Miller K, Buchanan G R, Zappa S, Cochran C, Laufenberg J, Medeiros D. et al . Implantable venous access devices in children with hemophilia: a report of low infection rates.  J Pediatr. 1998;  132 934-938
  • 39 Chatzinikolaou I, Zipf T F, Hanna H, Umphrey J, Roberts W M, Sherertz R. et al . Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer.  Clin Infect Dis. 2003;  36 116-119
  • 40 Ivanov R, Allen J, Calvin J E. The incidence of major morbidity in critically ill patients managed with pulmonary artery catheters: a meta-analysis.  Crit Care Med. 2000;  28 615-619
  • 41 Ruesch S, Walder B, Tramer M R. Complications of central venous catheters: internal jugular versus subclavian access - a systematic review.  Crit Care Med. 2002;  30 454-460
  • 42 Bansmer G, Keith D, Tesluk H. Complications following use of indwelling catheters of inferior vena cava.  JAMA. 1958;  167 1606-1611
  • 43 Crane C. Venous interruption of septic thrombophlebitis.  N Engl J Med. 1960;  262 947-951
  • 44 Indar R. The dangers of indwelling polyethelene cannulae in deep veins.  Lancet. 1959;  1 284-287
  • 45 Goetz A M, Wagener M M, Miller J M, Muder R R. Risk of infection due to central venous catheters: effect of site of placement and catheter type.  Infect Control Hosp Epidemiol. 1998;  19 842-845
  • 46 Joynt G M, Kew J, Gomersall C D, Leung V Y, Liu E K. Deep venous thrombosis caused by femoral venous catheters in critically ill adult patients.  Chest. 2000;  117 178-183
  • 47 Mian N Z, Bayly R, Schreck D M, Besserman E B, Richmand D. Incidence of deep venous thrombosis associated with femoral venous catheterization.  Acad Emerg Med. 1997;  4 1118-1121
  • 48 Durbec O, Viviand X, Potie F, Vialet R, Albanese J, Martin C. A prospective evaluation of the use of femoral venous catheters in critically ill adults.  Crit Care Med. 1997;  25 1986-1989
  • 49 Merrer J, Jonghe B De, Golliot F, Lefrant J Y, Raffy B, Barre E. et al . Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial.  JAMA. 2001;  286 700-707
  • 50 Trottier S J, Veremakis C, O'Brien J, Auer A I. Femoral deep vein thrombosis associated with central venous catheterization: results from a prospective, randomized trial.  Crit Care Med. 1995;  23 52-59
  • 51 Harden J L, Kemp L, Mirtallo J. Femoral catheters increase risk of infection in total parenteral nutrition patients.  Nutr Clin Pract. 1995;  10 60-66
  • 52 Kemp L, Burge J, Choban P, Harden J, Mirtallo J, Flancbaum L. The effect of catheter type and site on infection rates in total parenteral nutrition patients.  JPEN J Parenter Enteral Nutr. 1994;  18 71-74
  • 53 Sznajder J I, Zveibil F R, Bitterman H, Weiner P, Bursztein S. Central vein catheterization. Failure and complication rates by three percutaneous approaches.  Arch Intern Med. 1986;  146 259-261
  • 54 Mermel L. Central venous catheter-related infections and their prevention: is there enough evidence to recommend tunneling for short-term use?.  Crit Care Med. 1998;  26 1315-1316
  • 55 Mermel L A, McCormick R D, Springman S R, Maki D G. The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: a prospective study utilizing molecular subtyping.  Am J Med. 1991;  91 197S-205S
  • 56 Heard S O, Wagle M, Vijayakumar E, McLean S, Brueggemann A, Napolitano L M. et al . Influence of triple-lumen central venous catheters coated with chlorhexidine and silver sulfadiazine on the incidence of catheter-related bacteremia.  Arch Intern Med. 1998;  158 81-87
  • 57 Richet H, Hubert B, Nitemberg G, Andremont A, Buu-Hoi A, Ourbak P. et al . Prospective multicenter study of vascular-catheter-related complications and risk factors for positive central-catheter cultures in intensive care unit patients.  J Clin Microbiol. 1990;  28 2520-2525
  • 58 Richards B, Chaboyer W, Bladen T, Schluter P J. Effect of central venous catheter type on infections: a prospective clinical trial.  J Hosp Infect. 2003;  54 10-17
  • 59 Macdonald S, Watt A J, McNally D, Edwards R D, Moss J G. Comparison of technical success and outcome of tunneled catheters inserted via the jugular and subclavian approaches.  J Vasc Interv Radiol. 2000;  11 225-231
  • 60 Rosen M, Latto I P, Shang Ng W. Handbook of percutaneous central venous catheterisation. London, Toronto, Philadelphia, Marrickville; WB Saunders Company Ltd 1992
  • 61 Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut . Prävention Gefäßkatheterassoziierter Infektionen - Empfehlung der Kommission für Krankenhaushygiene und Infektionsprävention beim Robert Koch-Institut (RKI).  Bundesgesundheitsbl - Gesundheitsforsch - Gesundheitsschutz. 2002;  45 904-927
  • 62 Fletcher S J, Bodenham A R. Safe placement of central venous catheters: where should the tipp of the catheter lie?.  Br J Anaesth. 2000;  85 188-191
  • 63 Bozzetti F, Mariani L, Bertinet D B, Chiavenna G, Crose N, Cicco M De. et al . Central venous catheter (CVC) complications in 447 pts on home parenteral nutrition (HPN).  Clin Nutr. 2001;  20 31
  • 64 Bozzetti F, Mariani L, Bertinet D B, Chiavenna G, Crose N, Cicco M De. et al . Central venous catheter complications in 447 patients on home parenteral nutrition: an analysis of over 100.000 catheter days.  Clin Nutr. 2002;  21 475-485
  • 65 Cowl C T, Weinstock J V, Al Jurf A, Ephgrave K, Murray J A, Dillon K. Complications and cost associated with parenteral nutrition delivered to hospitalized patients through either subclavian or peripherally-inserted central catheters.  Clin Nutr. 2000;  19 237-243
  • 66 Duerksen D R, Papineau N, Siemens J, Yaffe C. Peripherally inserted central catheters for parenteral nutrition: a comparison with centrally inserted catheters.  JPEN J Parenter Enteral Nutr. 1999;  23 85-89
  • 67 Smith J R, Friedell M L, Cheatham M L, Martin S P, Cohen M J, Horowitz J D. Peripherally inserted central catheters revisited.  Am J Surg. 1998;  176 208-211
  • 68 Ng P K, Ault M J, Ellrodt A G, Maldonado L. Peripherally inserted central catheters in general medicine.  Mayo Clin Proc. 1997;  72 225-233
  • 69 Venkataraman S T, Thomson A E, Orr R A. Femoral vascular catheterisation in critically ill infants and children.  Clin Pediatr. 1997;  36 311-319
  • 70 Goldstein A M, Weber J M, Sheridan R L. Femoral venous access is safe in burned children: an analysis of 224 catheters.  J Pediatr. 1997;  130 442-446
  • 71 Stenzel J P, Green T P, Fuhrman B P, Carlson P E, Marchessault R P. Percutaneous femoral venous catheterizations: a prospective study of complications.  J Pediatr. 1989;  114 411-415
  • 72 Pomp A, Caldwell M D, Field J, Feitelson M, Varella L, Albina J. Seldinger technique for central venous catheter insertions, a prospective study of 200 cases.  Clin Nutr. 1987;  6 103
  • 73 Miller J A, Singireddy S, Maldjian P, Baker S R. A reevaluation of the radiographically detectable complications of percutaneous venous access lines inserted by four subcutaneous approaches.  Am Surg. 1999;  65 125-130
  • 74 Fisher K L, Leung A N. Radiographic appearance of central venous catheters.  AJR Am J Roentgenol. 1996;  166 329-337
  • 75 Caridi J G, West J H, Stavropoulos S W, Hawkins Jr I F. Internal jugular and upper extremity central venous access in interventional radiology: is a postprocedure chest radiograph necessary?.  AJR Am J Roentgenol. 2000;  174 363-366
  • 76 Randolph A G, Cook D J, Gonzales C A, Pribble C G. Ultrasound guidance for placement of central venous catheters: a meta-analysis of the literature.  Crit Care Med. 1996;  24 2053-2058
  • 77 Brass P, Volk O, Leben J, Schregel W. Zentralvenöse Punktion - nur noch mit Ultraschall?.  Anasthesiol Intensivmed Notfallmed Schmerzther. 2001;  36 619-627
  • 78 Keenan S P. Use of ultrasound to place central lines.  J Crit Care. 2002;  17 126-137
  • 79 Wagner H J, Teichgräber U, Gebauer B, Kalinowski M. Transjugular implantation of venous port catheter systems.  Röfo. 2003;  175 1539-1544
  • 80 Hind D, Calvert N, McWilliams R, Davidson A, Paisley S, Beverley C. et al . Ultrasonic locating devices for central venous cannulation: meta-analysis.  BMJ. 2003;  327 361
  • 81 Oguzkurt L, Tercan F, Kara G, Torun D, Kizilkilic O, Yildirim T. US-guided placement of temporary internal jugular vein catheters: immediate technical success and complications in normal and high-risk patients.  Eur J Radiol. 2005;  55 125-129
  • 82 Schäfer M, Reinhart K. Placement of central venous catheters using intra-arterial ECG recording.  Zentralbl Chir. 1993;  118 432-435
  • 83 McGee W T, Mallory D L, Johans T G. et al . Safe placement of central venous catheters is facilitated using right atrial electrocardiography.  Crit Care Med. 1988;  16 434
  • 84 Fritz K W, Gras C, Logemann F, Kirchhoff K. Positioning the central venous catheter using intra-atrial ECG.  Anaesthesiol Reanim. 1991;  16 399-402
  • 85 Nakatani K, Nishikawa K, Funao T, Ikeda Y, Nakasuji K, Iida Y. et al . Accurate placement of central venous catheter - ECG-guided method vs patient height method.  Masui. 2002;  51 34-38
  • 86 Madias J E. Intracardiac (superior vena cava/right atrial) ECGs using saline solution as the conductive medium for the proper positioning of the Shiley hemodialysis catheter: is it not time to forego [correction of forgo] the postinsertion chest radiograph?.  Chest. 2003;  124 2363-2367
  • 87 Madias J E. Intracardiac electrocardiography via a „saline-filled central venous catheter electrocardiographic lead”: a historical perspective.  J Electrocardiol. 2004;  37 83-88
  • 88 Schummer W, Herrmann S, Schummer C, Funke F, Steenbeck J, Fuchs J. et al . Intra-atrial ECG is not a reliable method for positioning left internal jugular vein catheters.  Br J Anaesth. 2003;  91 481-486
  • 89 Watters V A, Grant J P. Use of electrocardiogram to position right atrial catheters during surgery.  Ann Surg. 1997;  225 165-171
  • 90 Chu K S, Hsu J H, Wang S S, Tang C S, Cheng K I, Wang C K. et al . Accurate central venous port-A catheter placement: intravenous electrocardiography and surface landmark techniques compared by using transesophageal echocardiography.  Anesth Analg. 2004;  98 910 - 4, table
  • 91 Madan M, Shah M V, Alexander D J, Taylor C, McMahon M J. Right atrial electrocardiography: a technique for the placement of central venous catheters for chemotherapy or intravenous nutrition.  Br J Surg. 1994;  81 1604-1605
  • 92 McGee W T, Ackerman B L, Rouben L R, Prasad V M, Bandi V, Mallory D L. Accurate placement of central venous catheters: a prospective, randomized, multicenter trial.  Crit Care Med. 1993;  21 1118-1123
  • 93 Corsten S A, Dijk B van, Bakker N C, Lange J J de, Scheffer G J. Central venous catheter placement using the ECG-guided Cavafix-Certodyn SD catheter.  J Clin Anesth. 1994;  6 469-472
  • 94 Nachnani G H, Lessin L S, Motomiya T, Jensen W N. Scanning electron microscopy of thrombogenesis on vascular catheter surfaces.  N Engl J Med. 1972;  286 139-140
  • 95 Stillman R M, Soliman F, Garcia L, Sawyer P N. Etiology of catheter-associated sepsis. Correlation with thrombogenicity.  Arch Surg. 1977;  112 1497-1499
  • 96 Borow M, Crowley J G. Evaluation of central venous catheter thrombogenicity.  Acta Anaesthesiol Scand Suppl. 1985;  81 59-64
  • 97 Sheth N K, Franson T R, Rose H D, Buckmire F L, Cooper J A, Sohnle P G. Colonization of bacteria on polyvinyl chloride and Teflon intravascular catheters in hospitalized patients.  J Clin Microbiol. 1983;  18 1061-1063
  • 98 Maki D G, Ringer M. Evaluation of dressing regimens for prevention of infection with peripheral intravenous catheters. Gauze, a transparent polyurethane dressing, and an iodophor-transparent dressing.  JAMA. 1987;  258 2396-2403
  • 99 Maki D G, Ringer M. Risk factors for infusion-related phlebitis with small peripheral venous catheters. A randomized controlled trial.  Ann Intern Med. 1991;  114 845-854
  • 100 Locci R, Peters G, Pulverer G. Microbial colonization of prosthetic devices. IV. Scanning electron microscopy of intravenous catheters invaded by yeasts.  Zentralbl Bakteriol Mikrobiol Hyg [B]. 1981;  173 419-424
  • 101 Locci R, Peters G, Pulverer G. Microbial colonization of prosthetic devices. I. Microtopographical characteristics of intravenous catheters as detected by scanning electron microscopy.  Zentralbl Bakteriol Mikrobiol Hyg [B]. 1981;  173 285-292
  • 102 Branchini M L, Pfaller M A, Rhine-Chalberg J, Frempong T, Isenberg H D. Genotypic variation and slime production among blood and catheter isolates of Candida parapsilosis.  J Clin Microbiol. 1994;  32 452-456
  • 103 Marin M G, Lee J C, Skurnick J H. Prevention of nosocomial bloodstream infections: effectiveness of antimicrobial-impregnated and heparin-bonded central venous catheters.  Crit Care Med. 2000;  28 3332-3338
  • 104 Carrasco M N, Bueno A, Cuerus C de las, Jimenez S, Salinas I, Sartorius A. et al . Evaluation of a triple-lumen central venous heparin-coated catheter versus a catheter coated with chlorhexidine and silver sulfadiazine in critically ill patients.  Intensive Care Med. 2004;  30 633-638
  • 105 Foley P L, Barthel C H, Brausa H R. Effect of covalently bound heparin coating on patency and biocompatibility of long-term indwelling catheters in the rat jugular vein.  Comp Med. 2002;  52 243-248
  • 106 Nasuno A, Matsubara T, Hori T, Higuchi K, Tsuchida K, Mezaki T. et al . Acute pulmonary thromboembolism induced by prophylactic heparin use and a heparin-coated catheter: a case of heparin-induced thrombocytopenia and thrombosis syndrome.  Circ J. 2003;  67 96-98
  • 107 Laster J L, Nichols W K, Silver D. Thrombocytopenia associated with heparin-coated catheters in patients with heparin-associated antiplatelet antibodies.  Arch Intern Med. 1989;  149 2285-2287
  • 108 Tokars J I, Cookson S T, McArthur M A, Boyer C L, McGeer A J, Jarvis W R. Prospective evaluation of risk factors for bloodstream infection in patients receiving home infusion therapy.  Ann Intern Med. 1999;  131 340-347
  • 109 Gil R T, Kruse J A, Thill-Baharozian M C, Carlson R W. Triple- vs single-lumen central venous catheters. A prospective study in a critically ill population.  Arch Intern Med. 1989;  149 1139-1143
  • 110 Hilton E, Haslett T M, Borenstein M T, Tucci V, Isenberg H D, Singer C. Central catheter infections: single- versus triple-lumen catheters. Influence of guide wires on infection rates when used for replacement of catheters.  Am J Med. 1988;  84 667-672
  • 111 McCarthy M C, Shives J K, Robison R J, Broadie T A. Prospective evaluation of single and triple lumen catheters in total parenteral nutrition.  JPEN J Parenter Enteral Nutr. 1987;  11 259-262
  • 112 Pemberton L B, Lyman B, Lander V, Covinsky J. Sepsis from triple- vs single-lumen catheters during total parenteral nutrition in surgical or critically ill patients.  Arch Surg. 1986;  121 591-594
  • 113 Ma T Y, Yoshinaka R, Banaag A, Johnson B, Davis S, Berman S M. Total parenteral nutrition via multilumen catheters does not increase the risk of catheter-related sepsis: a randomized, prospective study.  Clin Infect Dis. 1998;  27 500-503
  • 114 Savage A P, Picard M, Hopkins C C, Malt R A. Complications and survival of multilumen central venous catheters used for total parenteral nutrition.  Br J Surg. 1993;  80 1287-1290
  • 115 Manglano R, Martin M. Safety of triple lumen catheters in the critically ill.  Am Surg. 1991;  57 370-372
  • 116 Attar A, Messing B. Evidence-based prevention of catheter infection during parenteral nutrition.  Curr Opin Clin Nutr Metab Care. 2001;  4 211-218
  • 117 Raad I I, Hohn D C, Gilbreath B J, Suleiman N, Hill L A, Bruso P A. et al . Prevention of central venous catheter-related infections by using maximal sterile barrier precautions during insertion.  Infect Control Hosp Epidemiol. 1994;  15 231-238
  • 118 Maki D G, Ringer M, Alvarado C J. Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters.  Lancet. 1991;  338 339-343
  • 119 Alonso-Echanove J, Edwards J R, Richards M J, Brennan P, Venezia R A, Keen J. et al . Effect of nurse staffing and antimicrobial-impregnated central venous catheters on the risk for bloodstream infections in intensive care units.  Infect Control Hosp Epidemiol. 2003;  24 916-925
  • 120 Abi-Said D, Raad I, Umphrey J, Gonzalez V, Richardson D, Marts K. et al . Infusion therapy team and dressing changes of central venous catheters.  Infect Control Hosp Epidemiol. 1999;  20 101-105
  • 121 Humar A, Ostromecki A, Direnfeld J, Marshall J C, Lazar N, Houston P C. et al . Prospective randomized trial of 10 % povidone-iodine versus 0.5 % tincture of chlorhexidine as cutaneous antisepsis for prevention of central venous catheter infection.  Clin Infect Dis. 2000;  31 1001-1007
  • 122 Garland J S, Buck R K, Maloney P, Durkin D M, Toth-Lloyd S, Duffy M. et al . Comparison of 10 % povidone-iodine and 0.5 % chlorhexidine gluconate for the prevention of peripheral intravenous catheter colonization in neonates: a prospective trial.  Pediatr Infect Dis J. 1995;  14 510-516
  • 123 Safdar N, Kluger D M, Maki D G. A review of risk factors for catheter-related bloodstream infection caused by percutaneously inserted, noncuffed central venous catheters: implications for preventive strategies.  Medicine (Baltimore). 2002;  81 466-479
  • 124 Ranson M R, Oppenheim B A, Jackson A, Kamthan A G, Scarffe J H. Double-blind placebo controlled study of vancomycin prophylaxis for central venous catheter insertion in cancer patients.  J Hosp Infect. 1990;  15 95-102
  • 125 Ljungman P, Hagglund H, Bjorkstrand B, Lonnqvist B, Ringden O. Peroperative teicoplanin for prevention of gram-positive infections in neutropenic patients with indwelling central venous catheters: a randomized, controlled study.  Support Care Cancer. 1997;  5 485-488
  • 126 Do A N, Ray B J, Banerjee S N, Illian A F, Barnett B J, Pham M H. et al . Bloodstream infection associated with needleless device use and the importance of infection-control practices in the home health care setting.  J Infect Dis. 1999;  179 442-448
  • 127 Gosbell I B. Central venous catheter related sepsis: epidemiology, pathogenesis, diagnosis, treatment and prevention.  Int Care World. 1994;  11 54-59
  • 128 Hoffmann K K, Weber D J, Samsa G P, Rutala W A. Transparent polyurethane film as an intravenous catheter dressing. A meta-analysis of the infection risks.  JAMA. 1992;  267 2072-2076
  • 129 Maki D G, Stolz S S, Wheeler S, Mermel L A. A prospective, randomized trial of gauze and two polyurethane dressings for site care of pulmonary artery catheters: implications for catheter management.  Crit Care Med. 1994;  22 1729-1737
  • 130 Bijma R, Girbes A R, Kleijer D J, Zwaveling J H. Preventing central venous catheter-related infection in a surgical intensive-care unit.  Infect Control Hosp Epidemiol. 1999;  20 618-620
  • 131 Laura R, Degl'Innocenti M, Mocali M, Alberani F, Boschi S, Giraudi A. et al . Comparison of two different time interval protocols for central venous catheter dressing in bone marrow transplant patients: results of a randomized, multicenter study. The Italian Nurse Bone Marrow Transplant Group (GITMO).  Haematologica. 2000;  85 275-279
  • 132 Madeo M, Martin C R, Turner C, Kirkby V, Thompson D R. A randomized trial comparing Arglaes (a transparent dressing containing silver ions) to Tegaderm (a transparent polyurethane dressing) for dressing peripheral arterial catheters and central vascular catheters.  Intensive Crit Care Nurs. 1998;  14 187-191
  • 133 Armstrong C W, Mayhall C G, Miller K B, Newsome Jr H H, Sugerman H J, Dalton H P. et al . Prospective study of catheter replacement and other risk factors for infection of hyperalimentation catheters.  J Infect Dis. 1986;  154 808-816
  • 134 Nehme A E. Nutritional support of the hospitalized patient. The team concept.  JAMA. 1980;  243 1906-1908
  • 135 Soifer N E, Borzak S, Edlin B R, Weinstein R A. Prevention of peripheral venous catheter complications with an intravenous therapy team: a randomized controlled trial.  Arch Intern Med. 1998;  158 473-477
  • 136 Tomford J W, Hershey C O. The i. v. therapy team: impact on patient care and costs of hospitalization.  NITA. 1985;  8 387-389
  • 137 Sherertz R J, Ely E W, Westbrook D M, Gledhill K S, Streed S A, Kiger B. et al . Education of physicians-in-training can decrease the risk for vascular catheter infection.  Ann Intern Med. 2000;  132 641-648
  • 138 Ryan Jr J A, Abel R M, Abbott W M, Hopkins C C, Chesney T M, Colley R. et al . Catheter complications in total parenteral nutrition. A prospective study of 200 consecutive patients.  N Engl J Med. 1974;  290 757-761
  • 139 Sanders R A, Sheldon G F. Septic complications of total parenteral nutrition. A five year experience.  Am J Surg. 1976;  132 214-220
  • 140 Murphy L M, Lipman T O. Central venous catheter care in parenteral nutrition: a review.  JPEN J Parenter Enteral Nutr. 1987;  11 190-201
  • 141 Eggimann P, Harbarth S, Constantin M N, Touveneau S, Chevrolet J C, Pittet D. Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care.  Lancet. 2000;  355 1864-1868
  • 142 Safdar N, Maki D G. The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters.  Intensive Care Med. 2004;  30 62-67
  • 143 Cook D, Randolph A, Kernerman P, Cupido C, King D, Soukup C. et al . Central venous catheter replacement strategies: a systematic review of the literature.  Crit Care Med. 1997;  25 1417-1424
  • 144 Maki D G, Stolz S M, Wheeler S, Mermel L A. Prevention of central venous catheter-related bloodstream infection by use of an antiseptic-impregnated catheter. A randomized, controlled trial.  Ann Intern Med. 1997;  127 257-266
  • 145 Fraenkel D, Rickard C, Thomas P, Faoagali J, George N, Ware R. A prospective, randomized trial of rifampicin-minocycline-coated and silver-platinum-carbon-impregnated central venous catheters.  Crit Care Med. 2006;  34 668-675
  • 146 Veenstra D L, Saint S, Saha S, Lumley T, Sullivan S D. Efficacy of antiseptic-impregnated central venous catheters in preventing catheter-related bloodstream infection: a meta-analysis.  JAMA. 1999;  281 261-267
  • 147 Jaeger K, Zenz S, Juttner B, Ruschulte H, Kuse E, Heine J. et al . Reduction of catheter-related infections in neutropenic patients: a prospective controlled randomized trial using a chlorhexidine and silver sulfadiazine-impregnated central venous catheter.  Ann Hematol. 2005;  84 258-262
  • 148 Khare M D, Bukhari S S, Swann A, Spiers P, McLaren I, Myers J. Reduction of catheter-related colonisation by the use of a silver zeolite-impregnated central vascular catheter in adult critical care. J Infect 2006 (in press)
  • 149 Benezra D, Kiehn T E, Gold J W, Brown A E, Turnbull A D, Armstrong D. Prospective study of infections in indwelling central venous catheters using quantitative blood cultures.  Am J Med. 1988;  85 495-498
  • 150 Darouiche R O, Raad I I, Heard S O, Thornby J I, Wenker O C, Gabrielli A. et al . A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group.  N Engl J Med. 1999;  340 1-8
  • 151 Hanna H A, Raad I I, Hackett B, Wallace S K, Price K J, Coyle D E. et al . Antibiotic-impregnated catheters associated with significant decrease in nosocomial and multidrug-resistant bacteremias in critically ill patients.  Chest. 2003;  124 1030-1038
  • 152 Leon C, Ruiz-Santana S, Rello J, Torre M V de la, Valles J, Alvarez-Lerma F. et al . Benefits of minocycline and rifampin-impregnated central venous catheters. A prospective, randomized, double-blind, controlled, multicenter trial.  Intensive Care Med. 2004;  30 1891-1899
  • 153 Yucel N, Lefering R, Maegele M, Max M, Rossaint R, Koch A. et al . Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.  J Antimicrob Chemother. 2004;  54 1109-1115
  • 154 Collin G R. Decreasing catheter colonization through the use of an antiseptic-impregnated catheter: a continuous quality improvement project.  Chest. 1999;  115 1632-1640
  • 155 Boswald M, Lugauer S, Regenfus A, Braun G G, Martus P, Geis C. et al . Reduced rates of catheter-associated infection by use of a new silver-impregnated central venous catheter.  Infection. 1999;  27, Suppl 1 S56-S60
  • 156 Rupp M E, Lisco S J, Lipsett P A, Perl T M, Keating K, Civetta J M. et al . Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial.  Ann Intern Med. 2005;  143 570-580
  • 157 Veenstra D L, Saint S, Sullivan S D. Cost-effectiveness of antiseptic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection.  JAMA. 1999;  282 554-560
  • 158 Arenas-Marquez H, Anaya-Prado R, Barrera-Zepeda L M, Gonzalez-Ojeda A. Complications of central venous catheters.  Curr Opin Clin Nutr Metab Care. 2001;  4 207-210
  • 159 Bennegard K, Curelaru I, Gustavsson B, Linder L E, Zachrisson B F. Material thrombogenicity in central venous catheterization. I. A comparison between uncoated and heparin-coated, long antebrachial, polyethylene catheters.  Acta Anaesthesiol Scand. 1982;  26 112-120
  • 160 Mollenholt P, Eriksson I, Andersson T. Thrombogenicity of pulmonary-artery catheters.  Intensive Care Med. 1987;  13 57-59
  • 161 Bern M M, Lokich J J, Wallach S R, Bothe Jr A, Benotti P N, Arkin C F. et al . Very low doses of warfarin can prevent thrombosis in central venous catheters. A randomized prospective trial.  Ann Intern Med. 1990;  112 423-428
  • 162 Boraks P, Seale J, Price J, Bass G, Ethell M, Keeling D. et al . Prevention of central venous catheter associated thrombosis using minidose warfarin in patients with haematological malignancies.  Br J Haematol. 1998;  101 483-486
  • 163 Couban S, Goodyear M, Burnell M, Dolan S, Wasi P, Barnes D. et al . Randomized placebo-controlled study of low-dose warfarin for the prevention of central venous catheter-associated thrombosis in patients with cancer.  J Clin Oncol. 2005;  23 4063-4069
  • 164 Klerk C P, Smorenburg S M, Buller H R. Thrombosis prophylaxis in patient populations with a central venous catheter: a systematic review.  Arch Intern Med. 2003;  163 1913-1921
  • 165 Verso M, Agnelli G, Bertoglio S, Somma F C di, Paoletti F, Ageno W. et al . Enoxaparin for the prevention of venous thromboembolism associated with central vein catheter: a double-blind, placebo-controlled, randomized study in cancer patients.  J Clin Oncol. 2005;  23 4057-4062
  • 166 Bethune K, Allwood M, Grainger C, Wormleighton C. Use of filters during the preparation and administration of parenteral nutrition: position paper and guidelines prepared by a British pharmaceutical nutrition group working party.  Nutrition. 2001;  17 403-408
  • 167 Lumpkin M M. Safety alert: hazards of precipitation associated with parenteral nutrition.  Am J Hosp Pharm. 1994;  51 1427-1428
  • 168 Ball P A, Bethune K M, Fox J C. et al . Particulate contamination in parenteral nutrition solutions, still cause for concern.  Clin Nutr. 1999;  18 14
  • 169 Ball P A. Intravenous in-line filters: filtering the evidence.  Curr Opin Clin Nutr Metab Care. 2003;  6 319-325
  • 170 Newall F, Ranson K, Robertson J. Use of in-line filters in pediatric intravenous therapy.  J Intraven Nurs. 1998;  21 166-170
  • 171 Krzywda E A. Predisposing factors, prevention, and management of central venous catheter occlusions.  J Intraven Nurs. 1999;  22 S11-S17
  • 172 Monturo C A, Dickerson R N, Mullen J L. Efficacy of thrombolytic therapy for occlusion of long-term catheters.  JPEN J Parenter Enteral Nutr. 1990;  14 312-314
  • 173 Gale G B, O'Connor D M, Chu J Y, Stanley D. Restoring patency of thrombosed catheters with cryopreserved urokinase.  JPEN J Parenter Enteral Nutr. 1984;  8 298-299
  • 174 Fraschini G, Jadeja J, Lawson M, Holmes F A, Carrasco H C, Wallace S. Local infusion of urokinase for the lysis of thrombosis associated with permanent central venous catheters in cancer patients.  J Clin Oncol. 1987;  5 672-678
  • 175 Rumsey K A, Richardson D K. Management of infection and occlusion associated with vascular access devices.  Semin Oncol Nurs. 1995;  11 174-183
  • 176 Camp-Sorrell D. Implantable ports: everything you always wanted to know.  J Intraven Nurs. 1992;  15 262-273
  • 177 Main J, Pennington C R. Catheter blockage with lipid during long-term parenteral nutrition.  Br Med J. 1984;  289 734
  • 178 Pennington C R, Pithie A D. Ethanol lock in the management of catheter occlusion.  JPEN J Parenter Enteral Nutr. 1987;  11 507-508
  • 179 Mühlebach S. Was der praktizierende Arzt vom Umgang mit Infusionen wissen muss.  Praxis, Schweizerische Rundschau für Medizin. 2001;  90 546-548
  • 180 Allwood M C, Kearney M C. Compatibility and stability of additives in parenteral nutrition admixtures.  Nutrition. 1998;  14 697-706
  • 181 Stennett D J, Gerwick W H, Egging P K, Christensen J M. Precipitate analysis from an indwelling total parenteral nutrition catheter.  JPEN J Parenter Enteral Nutr. 1988;  12 88-92
  • 182 Shulman R J, Reed T, Pitre D, Laine L. Use of hydrochloric acid to clear obstructed central venous catheters.  JPEN J Parenter Enteral Nutr. 1988;  12 509-510
  • 183 Duffy L F, Kerzner B, Gebus V, Dice J. Treatment of central venous catheter occlusions with hydrochloric acid.  J Pediatr. 1989;  114 1002-1004
  • 184 Goodwin M L. Using sodium bicarbonate to clear a medication precipitate from a central venous catheter.  JVAN. 1991;  1 23
  • 185 Holcombe B J, Forloines-Lynn S, Garmhausen L W. Restoring patency of long-term central venous access devices.  J Intraven Nurs. 1992;  15 36-41
  • 186 Siegman-Igra Y, Anglim A M, Shapiro D E, Adal K A, Strain B A, Farr B M. Diagnosis of vascular catheter-related bloodstream infection: a meta-analysis.  J Clin Microbiol. 1997;  35 928-936
  • 187 Mermel L A, Farr B M, Sherertz R J, Raad I I, O'Grady N, Harris J S. et al . Guidelines for the management of intravascular catheter-related infections.  Clin Infect Dis. 2001;  32 1249-1272
  • 188 Raad I I, Hanna H A. Intravascular catheter-related infections: new horizons and recent advances.  Arch Intern Med. 2002;  162 871-878
  • 189 Rijnders B J, Peetermans W E, Verwaest C, Wilmer A, Wijngaerden E van. Watchful waiting versus immediate catheter removal in ICU patients with suspected catheter-related infection: a randomized trial.  Intensive Care Med. 2004;  30 1073-1080
  • 190 Krzywda E A, Edmiston Jr C E. Central venous catheter infections. Clinical aspects of microbial etiology and pathogenesis.  J Infus Nurs. 2002;  25 29-35
  • 191 Forchielli M L, Gura K, Anessi-Pessina E, Richardson D, Cai W, Lo C W. Success rates and cost-effectiveness of antibiotic combinations for initial treatment of central-venous-line infections during total parenteral nutrition.  JPEN J Parenter Enteral Nutr. 2000;  24 119-125
  • 192 Sitges-Serra A, Girvent M. Catheter-related bloodstream infections.  World J Surg. 1999;  23 589-595
  • 193 Raad I, Hanna H A, Alakech B, Chatzinikolaou I, Johnson M M, Tarrand J. Differential time to positivity: a useful method for diagnosing catheter-related bloodstream infections.  Ann Intern Med. 2004;  140 18-25
  • 194 Dobbins B M, Catton J A, Kite P, McMahon M J, Wilcox M H. Each lumen is a potential source of central venous catheter-related bloodstream infection.  Crit Care Med. 2003;  31 1688-1690
  • 195 Raad I, Davis S, Becker M, Hohn D, Houston D, Umphrey J. et al . Low infection rate and long durability of nontunneled silastic catheters. A safe and cost-effective alternative for long-term venous access.  Arch Intern Med. 1993;  153 1791-1796
  • 196 Mayhall C G. Diagnosis and management of infections of implantable devices used for prolonged venous access.  Curr Clin Top Infect Dis. 1992;  12 83-110
  • 197 Hodge D, Puntis J W. Diagnosis, prevention, and management of catheter related bloodstream infection during long term parenteral nutrition.  Arch Dis Child Fetal Neonatal Ed. 2002;  87 F21-F24
  • 198 Sherertz R J, Heard S O, Raad I I. Diagnosis of triple-lumen catheter infection: comparison of roll plate, sonication, and flushing methodologies.  J Clin Microbiol. 1997;  35 641-646
  • 199 Fidalgo S, Vazquez F, Mendoza M C, Perez F, Mendez F J. Bacteremia due to Staphylococcus epidermidis: microbiologic, epidemiologic, clinical, and prognostic features.  Rev Infect Dis. 1990;  12 520-528
  • 200 Pollack P F, Kadden M, Byrne W J, Fonkalsrud E W, Ament M E. One hundred patient years' experience with the Broviac silastic catheter for central venous nutrition.  JPEN J Parenter Enteral Nutr. 1981;  5 32-36
  • 201 Raad I, Narro J, Khan A, Tarrand J, Vartivarian S, Bodey G P. Serious complications of vascular catheter-related Staphylococcus aureus bacteremia in cancer patients.  Eur J Clin Microbiol Infect Dis. 1992;  11 675-682
  • 202 Raad I, Davis S, Khan A, Tarrand J, Elting L, Bodey G P. Impact of central venous catheter removal on the recurrence of catheter-related coagulase-negative staphylococcal bacteremia.  Infect Control Hosp Epidemiol. 1992;  13 215-221
  • 203 Malanoski G J, Samore M H, Pefanis A, Karchmer A W. Staphylococcus aureus catheter-associated bacteremia. Minimal effective therapy and unusual infectious complications associated with arterial sheath catheters.  Arch Intern Med. 1995;  155 1161-1166
  • 204 Rose H D. Venous catheter-associated candidemia.  Am J Med Sci. 1978;  275 265-269
  • 205 Krzywda E A, Gotoff R, Andris D A, Marciniak T F, Edmiston D, Quebbeman E. Antibiotic lock treatment (ALT): impact on catheter salvage and cost savings. Program and Abstracts of the 35th Interscience Conference of Antimicrobial Agents and Chemotherapy. San Francisco, California; 1995
  • 206 Capedvila J, Segarra A, Planes A, Gasser I, Gavalda J, Pahissa A. Long-term follow-up of patients with catheter-related sepsis (CRS) treated without catheter removal. Program and Abstracts of the 35th Interscience Conference of Antimicrobial Agents and Chemotherapy. San Francisco, California; 1995
  • 207 Strinden W D, Helgerson R B, Maki D G. Candida septic thrombosis of the great central veins associated with central catheters. Clinical features and management.  Ann Surg. 1985;  202 653-658
  • 208 Raviglione M C, Battan R, Pablos-Mendez A, Aceves-Casillas P, Mullen M P, Taranta A. Infections associated with Hickman catheters in patients with acquired immunodeficiency syndrome.  Am J Med. 1989;  86 780-786
  • 209 Dugdale D C, Ramsey P G. Staphylococcus aureus bacteremia in patients with Hickman catheters.  Am J Med. 1990;  89 137-141
  • 210 Lecciones J A, Lee J W, Navarro E E, Witebsky F G, Marshall D, Steinberg S M. et al . Vascular catheter-associated fungemia in patients with cancer: analysis of 155 episodes.  Clin Infect Dis. 1992;  14 875-883
  • 211 O'Grady N P, Barie P S, Bartlett J, Bleck T, Garvey G, Jacobi J. et al . Practice parameters for evaluating new fever in critically ill adult patients. Task Force of the American College of Critical Care Medicine of the Society of Critical Care Medicine in collaboration with the Infectious Disease Society of America.  Crit Care Med. 1998;  26 392-408
  • 212 Messing B, Peitra-Cohen S, Debure A, Beliah M, Bernier J J. Antibiotic-lock technique: a new approach to optimal therapy for catheter-related sepsis in home-parenteral nutrition patients.  JPEN J Parenter Enteral Nutr. 1988;  12 185-189
  • 213 Andris D A, Krzywda E A, Edmiston C E, Krepel C J, Gohr C M. Elimination of intraluminal colonization by antibiotic lock in silicone vascular catheters.  Nutrition. 1998;  14 427-432
  • 214 Krzywda E A, Andris D A, Edmiston Jr C E, Quebbeman E J. Treatment of Hickman catheter sepsis using antibiotic lock technique.  Infect Control Hosp Epidemiol. 1995;  16 596-598
  • 215 Guggenbichler J P, Berchtold D, Allerberger F, Bonatti H, Hager J, Pfaller W. et al . In vitro and in vivo effect of antibiotics on catheters colonized by staphylococci.  Eur J Clin Microbiol Infect Dis. 1992;  11 408-415
  • 216 Rao J S, O'Meara A, Harvey T, Breatnach F. A new approach to the management of Broviac catheter infection.  J Hosp Infect. 1992;  22 109-116
  • 217 Benoit J L, Carandang G, Sitrin M, Arnow P M. Intraluminal antibiotic treatment of central venous catheter infections in patients receiving parenteral nutrition at home.  Clin Infect Dis. 1995;  21 1286-1288
  • 218 Messing B, Man F, Colimon R, Thuillier F, Beliah M. Antibiotic-lock technique is an effective treatment of bacterial catheter-related sepsis during parenteral nutrition.  Clin Nutr. 1990;  9 220-225
  • 219 Gaillard J L, Merlino R, Pajot N, Goulet O, Fauchere J L, Ricour C. et al . Conventional and nonconventional modes of vancomycin administration to decontaminate the internal surface of catheters colonized with coagulase-negative staphylococci.  JPEN J Parenter Enteral Nutr. 1990;  14 593-597
  • 220 Schwartz C, Henrickson K J, Roghmann K, Powell K. Prevention of bacteremia attributed to luminal colonization of tunneled central venous catheters with vancomycin-susceptible organisms.  J Clin Oncol. 1990;  8 1591-1597
  • 221 Henrickson K J, Axtell R A, Hoover S M, Kuhn S M, Pritchett J, Kehl S C. et al . Prevention of central venous catheter-related infections and thrombotic events in immunocompromised children by the use of vancomycin/ciprofloxacin/heparin flush solution: A randomized, multicenter, double-blind trial.  J Clin Oncol. 2000;  18 1269-1278
  • 222 Payne-James J J, Khawaja H T. First choice for total parenteral nutrition: the peripheral route.  JPEN J Parenter Enteral Nutr. 1993;  17 468-478
  • 223 Hansell D T. Intravenous nutrition: the central or peripheral route?.  Int Ther Clin Mon. 1989;  6/7 184-190
  • 224 Couse N, Pickford L R, Mitchell C J, Macfie J. Total parenteral nutrition by peripheral vein - Substitute or supplement to the central venous route? A prospective trial.  Clin Nutr. 1993;  12 213-216
  • 225 Everitt N J, Wong C, McMahon M J. Peripheral infusion as the route of choice for intravenous nutrition: a prospective two year study.  Clin Nutr. 1996;  15 69-74
  • 226 Kohlhardt S R, Smith R C, Wright C R, Sucic K A. Fine-bore peripheral catheters versus central venous catheters for delivery of intravenous nutrition.  Nutrition. 1992;  8 412-417
  • 227 Everitt N J, Madan M, Alexander D J, McMahon M J. Fine bore silicone rubber and polyurethane catheters for the delivery of complete intravenous nutrition via a peripheral vein.  Clin Nutr. 1993;  12 261-265
  • 228 Timmer J G, Schipper H G. Peripheral venous nutrition: the equal relevance of volume load and osmolarity in relation to phlebitis.  Clin Nutr. 1991;  10 71-75
  • 229 Kuwahara T, Asanami S, Tamura T, Kaneda S. Effects of pH and osmolality on phlebitic potential of infusion solutions for peripheral parenteral nutrition.  J Toxicol Sci. 1998;  23 77-85
  • 230 Kuwahara T, Asanami S, Kubo S. Experimental infusion phlebitis: tolerance osmolality of peripheral venous endothelial cells.  Nutrition. 1998;  14 496-501
  • 231 Gazitua R, Wilson K, Bistrian B R, Blackburn G L. Factors determining peripheral vein tolerance to amino acid infusions.  Arch Surg. 1979;  114 897-900
  • 232 Isaacs J W, Millikan W J, Stackhouse J, Hersh T, Rudman D. Parenteral nutrition of adults with a 900 milliosmolar solution via peripheral veins.  Am J Clin Nutr. 1977;  30 552-559
  • 233 Acra S A, Rollins C. Principles and guidelines for parenteral nutrition in children.  Pediatr Ann. 1999;  28 113-120
  • 234 Kane K F, Cologiovanni L, McKiernan J, Panos M Z, Ayres R C, Langman M J. et al . High osmolality feedings do not increase the incidence of thrombophlebitis during peripheral i. v. nutrition.  JPEN J Parenter Enteral Nutr. 1996;  20 194-197
  • 235 Williams N, Wales S, Irving M H. Prolonged peripheral parenteral nutrition with an ultrafine cannula and low-osmolality feed.  Br J Surg. 1996;  83 114-116
  • 236 Everitt N J, McMahon M J. Influence of fine-bore catheter length on infusion thrombophlebitis in peripheral intravenous nutrition: a randomised controlled trial.  Ann R Coll Surg Engl. 1997;  79 221-224
  • 237 Madan M, Alexander D J, McMahon M J. Influence of catheter type on occurrence of thrombophlebitis during peripheral intravenous nutrition.  Lancet. 1992;  339 101-103
  • 238 Hecker J F. Potential for extending survival of peripheral intravenous infusions.  BMJ. 1992;  304 619-624
  • 239 Everitt N J, McMahon M J. Peripheral intravenous nutrition.  Nutrition. 1994;  10 49-57
  • 240 Kuwahara T, Asanami S, Tamura T, Kubo S. Experimental infusion phlebitis: importance of titratable acidity on phlebitic potential of infusion solution.  Clin Nutr. 1996;  15 129-132
  • 241 Hessov I, Bojsen-Mooller M. Experimental infusion thrombophlebitis. Importance of the pH of glucose solutions.  Eur J Intensive Care Med. 1976;  2 97-101
  • 242 Lai K K. Safety of prolonging peripheral cannula and i. v. tubing use from 72 hours to 96 hours.  Am J Infect Control. 1998;  26 66-70
  • 243 Bregenzer T, Conen D, Sakmann P, Widmer A F. Is routine replacement of peripheral intravenous catheters necessary?.  Arch Intern Med. 1998;  158 151-156
  • 244 Cornely O A, Bethe U, Pauls R, Waldschmidt D. Peripheral Teflon catheters: factors determining incidence of phlebitis and duration of cannulation.  Infect Control Hosp Epidemiol. 2002;  23 249-253
  • 245 Shimandle R B, Johnson D, Baker M, Stotland N, Karrison T, Arnow P M. Safety of peripheral intravenous catheters in children.  Infect Control Hosp Epidemiol. 1999;  20 736-740
  • 246 Garland J S, Dunne Jr W M, Havens P, Hintermeyer M, Bozzette M A, Wincek J. et al . Peripheral intravenous catheter complications in critically ill children: a prospective study.  Pediatrics. 1992;  89 1145-1150
  • 247 Garland J S, Nelson D B, Cheah T E, Hennes H H, Johnson T M. Infectious complications during peripheral intravenous therapy with Teflon catheters: a prospective study.  Pediatr Infect Dis J. 1987;  6 918-921
  • 248 Nelson D B, Garland J S. The natural history of Teflon catheter-associated phlebitis in children.  Am J Dis Child. 1987;  141 1090-1092
  • 249 Maki D G, Mermel L A. Infections due to infusion therapy. In: Bennett JV, Brachman PS (eds) Hospital infections. Philadelphia; Lippencott-Raven 1998: 689-724
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