Ultraschall Med 2012; 33(7): E225-E232
DOI: 10.1055/s-0031-1299329
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

Gastrointestinal Wall Thickness Measured with Transabdominal Ultrasonography and Its Relationship to Demographic Factors in Healthy Subjects

Die Wanddicke des Magen-Darm-Traktes und seine Beziehung zu demografischen Faktoren bei gesunden Probanden, gemessen mit transabdominalem Ultraschall
K. Nylund
1   Institute of Medicine, University of Bergen
2   Department of Medicine, Haukeland University Hospital
,
T. Hausken
1   Institute of Medicine, University of Bergen
2   Department of Medicine, Haukeland University Hospital
,
S. Ødegaard
1   Institute of Medicine, University of Bergen
2   Department of Medicine, Haukeland University Hospital
,
G. E. Eide
3   Department of Public Health and Primary Healthcare, University of Bergen
4   Centre for Clinical Research, Haukeland University Hospital
,
O. H. Gilja
1   Institute of Medicine, University of Bergen
2   Department of Medicine, Haukeland University Hospital
› Author Affiliations
Further Information

Publication History

05 July 2011

11 August 2011

Publication Date:
13 April 2012 (online)

Abstract

Purpose: To describe the gastrointestinal (GI) wall thickness and the thickness of individual wall layers in healthy subjects using ultrasound and to determine whether demographic factors, the ultrasound transducer frequency, or a fasting state influences these measurements.

Materials and Methods: After overnight fasting, the GI wall thickness and wall layers were measured in several regions with transabdominal, high-frequency ultrasound. 122 healthy subjects aged 23 – 79 were included. All measurements were performed with both 8 and 12-MHz transducers except for the rectum measurement (4 MHz). 23 patients were given a 300 Kcal test meal and re-examined after 30 minutes.

Results: Wall thickness measurements of the GI tract with transabdominal ultrasonography are dependent on transducer frequency (p < 0.001), weight (p < 0.001) and age (p < 0.018). The thickness of individual wall layers in the ileum and the sigmoid colon was found to be dependent on both age (p = 0.007) and weight (p < 0.001). The mean wall thickness from the jejunum to the sigmoid colon ranged from 0.9 to 1.2 mm with standard deviations (SD) of 0.3 mm or less. The mean (SD) was 2.9 (0.8) mm in the gastric antrum, 1.6 (0.3) mm in the duodenum, and 2.1 (0.5) mm in the rectum. The gastric antrum was thinner and the ileum and sigmoid colon were thicker after the test meal (p < 0.05).

Conclusion: GI wall thickness depends on weight and age. Provided adequate measurement, an abnormal GI wall should be suspected if the thickness exceeds 2 mm except for in the gastric antrum, duodenum and rectum. Reference values for wall thickness can be used regardless of fasting state or probe frequency except for in the gastric antrum.

Zusammenfassung

Hintergrund: Die Wanddicke des Magen-Darm-Traktes (GI) und die Dicke der einzelnen Wandschichten wurden bei gesunden Probanden mithilfe von Ultraschall, unter Berücksichtigung von demografischen Faktoren, Ultraschallfrequenz und in zum Untersuchungszeitpunkt nüchternen Patienten untersucht.

Material und Methoden: An über Nacht nüchternen Probanden wurden Ultraschallmessungen der Magen-Darm-Wanddicke und Wandschichten in den Darmgebieten mehreren abdominalen Regionen mit transabdominalem Hochfrequenz-Ultraschall gemessen. 122 gesunde Probanden im Alter von 23 – 79 Jahren wurden eingeschlossen. Alle Messungen wurden mit einem 8 und einem 12 MHz-Schallkopf mit Ausnahme des Mastdarms (4 MHz) durchgeführt. 20 Patienten wurde eine 300 kcal Testmahlzeit gegeben und nach 30 min erneut untersucht.

Ergebnisse: Die Wanddickenmessung des GI-Traktes mit transabdominalem Ultraschall ist abhängig von Ultraschall-Frequenz (p < 0,001), Gewicht (p < 0,001) und Alter (p < 0,018). Die Dicke der einzelnen Wandschichten des Ileums und Colon sigmoideum erwies sich abhängig sowohl von Alter (p = 0,007) als auch Gewicht (p < 0,001). Die mittlere Wanddicke des Jejunums und Colon sigmoideum reichte von 0,9 – 1,2 mm mit Standardabweichungen (SD) 0,3 mm oder weniger. Im Magenantrum betrug der Mittelwert (SD) 2,9 (0,8) mm, im Zwölffingerdarm 1,6 (0,3) mm und im Rektum 2,1 (0,5) mm. Nach der Testmahlzeit (p < 0,05) war die Wand des Magenantrums dünner und die des Ileums und Sigmoids dicker.

Schlussfolgerung: Die Wanddicke im GI-Trakt ist abhängig von Gewicht und Alter. Sofern verlässliche Messungen durchgeführt werden, können eine abnormale GI-Wand vermutet werden, wenn die Wanddicke größer als 2 mm ist. Dies gilt nicht für das Antrum, Duodenum und Rektum. Mit Ausnahme des Antrums können Referenzwerte für die Wandstärke unabhängig vom nüchternen Zustand oder der Sondenfrequenz erhoben werden.

 
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