Original ResearchBrief ReportActivity of Mesothelin-Specific Chimeric Antigen Receptor T Cells Against Pancreatic Carcinoma Metastases in a Phase 1 Trial
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Acknowledgments
The authors thank the nurses of the Clinical Trials Research Center, Don Siegel Director of Transfusion Medicine and Therapeutic Pathology, and the staff of the Apheresis Unit at the Hospital of the University of Pennsylvania for their outstanding and dedicated patient care and careful data collection. We also acknowledge Natalka Kengle for cytokine luminex assays, Jeffrey Finklestein and Minnal Gupta for sample processing, Vanessa Gonzalez for data management and quality control, and Andrea
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Conflicts of interest The authors disclose the following: Bruce L. Levine, Carl H. June, Gregory L. Beatty, Gabriela Plesa, Simon F. Lacey, and J. Joseph Melenhorst are inventors of intellectual property related to chimeric antigen receptor T cells that is licensed by the University of Pennsylvania to Novartis. The remaining authors disclose no conflicts.
Funding This work was supported by a research grant funded by the Lustgarten Foundation and Cancer Research Institute. Additional support was provided in part by a Doris Duke Charitable Foundation Clinical Investigator Award (to G.L. Beatty) and by grant number K08 CA138907 (to G.L. Beatty) and 5R01 CA120409 (to Carl H. June).