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Adverse events associated with umbilical catheters: a systematic review and meta-analysis

Journal of Perinatology volume 41, pages 2505–2512 (2021)Cite this article

Subjects

Abstract

Objective

To determine the incidence of adverse events (AEs) associated with umbilical catheters in the neonatal population.

Study design

Systematic review and meta-analysis of observational studies and randomized controlled trials published between 2010 and 2020.

Results

In total 14,226 umbilical venous catheters (UVCs) and 4228 umbilical arterial catheters (UACs) were included. Overall, 13.4% of UVCs were associated with an AE (95% CI: 10.1–17.0) or 2.4 per 1000 catheter days (95% CI: 1.8–3.0). UACs had an AE rate of 9% (95% CI: 5.9–12.8) or 0.87 per 1000 catheter days (95% CI: 0.4–1.3). UVC malposition was the most common (41.7% [95% CI: 27.6–56.5]). Local injury from UAC taping was the most common AE in one study.

Conclusions

Umbilical catheters have a high incidence of AEs. Research into accurate methods of tip verification, tip surveillance, and securement is required.

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Authors and Affiliations

  1. Clinical and Health Sciences, Rosemary Bryant AO Research Centre, University of South Australia, Adelaide, SA, Australia

    Kim Gibson & Rebecca Sharp

  2. Children’s Health Queensland and Health Service, Centre of Children’s Health Research, South Brisbane, QLD, Australia

    Amanda Ullman

  3. School of Nursing, Midwifery and Social Work, The University of Queensland, Brisbane, QLD, Australia

    Amanda Ullman

  4. Neonatal Unit, Flinders Medical Centre, Bedford Park, SA, Australia

    Scott Morris

  5. College of Medicine and Public Health, Flinders University, Adelaide, Australia

    Scott Morris

  6. Queensland Children’s Hospital, South Brisbane, QLD, Australia

    Tricia Kleidon

  7. Clinical and Health Sciences, Rosemary Bryant AO Research Centre, University of South Australia, Adelaide, SA, Australia

    Adrian Esterman

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Contributions

All authors have approved the final article, have made substantial contributions to the review, are accountable for the work presented and acknowledge that they are entitled to authorship of this article. KG was responsible for investigation, writing-original draft preparation, RS for investigation, writing-reviewing, supervision, AU for investigation, writing-reviewing, supervision, SM for writing-reviewing, industry expertise, TK for writing-reviewing, industry expertise and AE for conceptualization, writing-reviewing, supervision.

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Correspondence to Kim Gibson.

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The above authors have no competing interests to declare. Independent from the reported project, Griffith University has received investigator-initiated research and educational grants from product manufacturers (3M, Becton Dickinson, Cardinal Health), to support research led by AU. Independent from this project, Griffith University has received investigator-initiated research and educational grants from product manufactures (3M, Access Scientific, BD/Bard, Medical Specialties Australia, Vygon), to support research led by TK.

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Gibson, K., Sharp, R., Ullman, A. et al. Adverse events associated with umbilical catheters: a systematic review and meta-analysis. J Perinatol 41, 2505–2512 (2021). https://doi.org/10.1038/s41372-021-01147-x

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  • DOI: https://doi.org/10.1038/s41372-021-01147-x

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