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Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes

Prostate Cancer and Prostatic Diseases volume 12, pages 177–183 (2009)Cite this article

Abstract

The urologic chronic pain conditions such as chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis are syndromes whose evaluation and management are controversial. Part of the difficulty in diagnosis and therapy is the heterogeneity of etiologies and symptoms. We propose a six-domain phenotype, which can classify these patients clinically and can direct the selection of therapy in the most evidence based multimodal manner. The domains are urinary, psychosocial, organ specific, infection, neurologic and tenderness of skeletal muscles. This system is flexible and responsive to new biomarkers and therapies as their utility and efficacy are proven.

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Authors and Affiliations

  1. Glickman Urological and Kidney Institute, The Cleveland Clinic, Cleveland, OH, USA

    D A Shoskes & R R Rackley

  2. Department of Urology, Queens University, Kingston, Ontario, Canada

    J C Nickel

  3. Department of Urology, Temple University, Philadelphia, PA, USA

    M A Pontari

Authors
  1. D A Shoskes
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  2. J C Nickel
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  3. R R Rackley
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  4. M A Pontari
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Correspondence to D A Shoskes.

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Shoskes, D., Nickel, J., Rackley, R. et al. Clinical phenotyping in chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: a management strategy for urologic chronic pelvic pain syndromes. Prostate Cancer Prostatic Dis 12, 177–183 (2009). https://doi.org/10.1038/pcan.2008.42

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