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Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes

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Acknowledgements

This work was supported in part by funding from the Leukemia and Lymphoma Society Translational Research Program to S Lonial. Panobinostat was provided by Novartis. We thank Lauren Moss for assistance with IVIS imaging and platelet counts, Dr Ying Lu for transfection of LBRM-33 with the luciferase vector and the Biostatistics Shared Core Resource at the Winship Cancer Institute for assistance with statistical methods.

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Correspondence to C R Giver.

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S Lonial has received consultant and research support from Novartis. The other authors have no conflict of interest. The writing and interpretation and editorial control of the data and the manuscript were fully under the control of the authors.

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Giver, C., Jaye, D., Waller, E. et al. Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes. Leukemia 25, 362–365 (2011). https://doi.org/10.1038/leu.2010.262

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