Abstract
A prospective study was carried out to assess the recurrence rate of pterygium with conjunctival auto-graft versus the use of topical mitomycin C. In 27 eyes undergoing pterygium excision with conjunctival autograft, the recurrence rate was found to be 25.9% after 1 year mean follow-up. In the second group of 32 eyes, pterygium was removed using the bare sclera method. All these patients received post-operatively 0.2 mg/ml (0.02%) topical mitomycin C twice a day for 5 days. At 1 year mean follow-up, the recurrence rate in this group was 9.4%. Although the difference was not statistically significant, the number of recurrences was lower in the mitomycin-C-treated group than in patients undergoing conjunctival autograft.
Similar content being viewed by others
Article PDF
References
Kenyon KR, Wagoner MD, Hettinger ME . Conjunctival autograft transplantation for advanced and recurrent pterygium. Ophthalmology 1985;92:1461–70.
Mahar PS, Nwokora GE . Role of mitomycin C in pterygium surgery. Br J Ophthalmol 1993;77:433–5.
Polit F, Matheen M . Conjunctival autograft for advanced and recurrent pterygium in Saudi Arabia. Saudi J Ophthalmol 1991;5:171–4.
Mackenzie FD, Hirst LW, Battistutta D, Green A . Risk analysis in the development of pterygia. Ophthalmology 1992;99:1056–61.
Hayasaka S, Noda S, Yamamoto Y, Setogawa T . Postoperative instillation of low dose mitomycin C in the treatment of primary pterygium. Am J Ophthalmol 1988;106:715–8.
Sing G, Wilson MR, Foster CS . Mitomycin eye drops as treatment for pterygium. Ophthalmology 1988;95:813–20.
Frucht-Pery J, Islar M . The use of low dose mitomycin C for prevention of recurrent pterygium. Ophthalmology 1994;101:759–62.
Rubinfeld RS, Pfister RR, Stein RM . Serious complications of topical mitomycin C after pterygium surgery. Ophthalmology 1992;99:1647–54.
Gupta S, Bastis S . Corneoscleral, ciliary body and vitreoretinal toxicity after excessive instillation of mitomycin C. Am J Ophthalmol 1992;114:503–5.
Mahar PS . Role of mitomycin C in reducing the recurrence of pterygium after surgery. Pak J Ophthalmol 1996;12:113–6.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mahar, P. Conjunctival autograft versus topical mitomycin C in treatment of pterygium. Eye 11, 790–792 (1997). https://doi.org/10.1038/eye.1997.206
Issue Date:
DOI: https://doi.org/10.1038/eye.1997.206
Keywords
This article is cited by
-
Long-term comparison of limbal conjunctival autograft and bare sclera technique in pterygium surgery: a five-year follow-up trial
Spektrum der Augenheilkunde (2016)
-
The study of etiological and demographic characteristics of pterygium recurrence: a consecutive case series study from Pakistan
International Ophthalmology (2014)
-
The influence of pterygium morphology on fibrin glue conjunctival autografting pterygium surgery
International Ophthalmology (2014)
-
Pterygium treatment using 5-FU as adjuvant treatment compared to conjunctiva autograft
Eye (2008)
-
Conjunctival–Limbal Autograft, Amniotic Membrane Transplantation, and Intraoperative Mitomycin C for Primary Pterygium
Annals of Ophthalmology (2007)