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Structural biology

Conservation in vesicle coats

Nature volume 466, pages 1048–1049 (2010)Cite this article

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Coat proteins of vesicles involved in intracellular membrane trafficking have closely related molecular architectures. The structure of COPI extends known similarities, and strengthens the case for a common evolutionary origin.

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Figure 1: Schematic representation of coat proteins and their assemblies.

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Authors and Affiliations

  1. Stephen C. Harrison is in the Department of Biological Chemistry and Molecular Pharmacology and the Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA. harrison@crystal.harvard.edu,

    Stephen C. Harrison

  2. Tomas Kirchhausen is at the Immune Disease Institute and the Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.,

    Tomas Kirchhausen

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  1. Stephen C. Harrison
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  2. Tomas Kirchhausen
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Harrison, S., Kirchhausen, T. Conservation in vesicle coats. Nature 466, 1048–1049 (2010). https://doi.org/10.1038/4661048a

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