Article contents
Rapid reversal of dilated cardiomyopathy following removal of neuroblastoma
Published online by Cambridge University Press: 19 August 2008
Abstract
Reported is a child with dilated cardiomyopathy, in whom medical therapy resulted in a mild improvement of cardiac function. Metabolic studies suggested the presence of a catecholamine-secreting tumour; and an adrenal neuroblastoma was identified and surgically removed. Following surgery, there was progressive and complete normalization of cardiac function. Although very rare, neurogenic tumours may be involved in the development of a dilated cardiomyopathy in the infant and child.
- Type
- Brief Reports
- Information
- Copyright
- Copyright © Cambridge University Press 1999
References
1.Mestroni, L. Dilated cardiomyopathy: a genetic approach. Heart 1997; 77: 185–188.CrossRefGoogle ScholarPubMed
2.Sardesai, SH, Mourant, AJ, Sivathandon, Y, Farrow, R, Gibbons, DO. Phaeochromocytoma and catecholamine induced cardiomyopathy presenting as heart failure. Br Heart J. 1990; 63: 234–237.Google Scholar
3.Imperato-McGinley, J, Gautier, T, Ehlers, K, Zullo, MA, Goldstein, DS, Vaughan, ED. Reversibility of catecholamine induced dilated cardiomyopathy in a child with pheochromocytoma. N Engl J Med 1987; 316: 793–797.Google Scholar
4.Joseph, T, Olivier, B, Magnier, S, Brugiβres, L, Casasoprana, A. Catecholamine cardiomyopathy in neuroblastoma. Arch Pediatr 1997; 4: 32–35.CrossRefGoogle ScholarPubMed
5.Maris, JM. Are certain children more likely to develop neuroblastoma? J Pediatr 1997; 131: 656–657.Google ScholarPubMed
6.Weinblat, ME, Heisel, MA, Siegel, SE. Hypertension in children with neurogenic tumors. Pediatrics 1983; 71: 947–951.CrossRefGoogle Scholar
7.Schaffer, MS, Zuberbuhler, P, Wilson, G, Rose, V, Duncan, WJ, Rowe, RD. Catecholamine cardiomyopathy: an unusual presentation of pheochromocytoma in children. J Pediatr 1981; 99: 276–279.CrossRefGoogle ScholarPubMed
8.Gersony, WM. The child with dilated cardiomyopathy: prognostic considerations and management decisions. J Am Coll Cardiol 1991; 18: 157–158.Google Scholar
9.Limas, CJ. Cardiac autoantibodies in dilated cardiomyopathy. A pathogenetic role? Circulation 1997; 95: 1979–1980.CrossRefGoogle ScholarPubMed
10.Chen, L, Re, RN, Prakash, O, Mondal, D. Angiotensin-converting enzyme inhibition reduces neuroblastoma cell growth rate. PSEBM 1991; 196: 280–283.Google Scholar
- 12
- Cited by