Elsevier

The Lancet

Volume 325, Issue 8428, 9 March 1985, Pages 563-565
The Lancet

Hospital Practice
BLADDER IRRIGATION WITH POVIDONE-IODINE IN PREVENTION OF URINARY-TRACT INFECTIONS ASSOCIATED WITH INTERMITTENT URETHRAL CATHETERISATION

https://doi.org/10.1016/S0140-6736(85)91217-6Get rights and content

Abstract

Bladder irrigation with povidone-iodine in the prevention of urinary-tract infections after single or intermittent urethral catheterisation was investigated in a controlled study. In the control group (36 patients) the catheter was removed after urethral catheterisation and emptying of the bladder, and in the trial group (42 patients) 50 ml povidone-iodine 2% was instilled and allowed to drain immediately before removal of the catheter. The incidence of bacteriuria was 28% in the control group and 4% in the povidone-iodine group. After the introduction of bladder irrigation with povidone-iodine in the orthopaedic department of Leiden University Hospital the incidence of hospital-acquired bacteriuria fell from 6·9% to 3·7%.

References (33)

  • Wa Gillespie et al.

    Prevention of urinary infection by means of closed drainage into a sterile plastic bag

    Br Med J

    (1967)
  • Cm Martin et al.

    Bacteriuria prevention after indwelling urinary catheterization

    Arch Intern Med

    (1962)
  • Cm Martin et al.

    Prevention of gram-negative rod bacteremia associated with indwelling urinary-tract catheterization

    Antimicrob Agents Chemother

    (1963)
  • Ms Meyers et al.

    Controlled trial of nitrofurazone and neomycin-polymyxin as constant bladder rinses for prevention of postindwelling catheterization bacteriuria

    Antimicrob Agents Chemother

    (1964)
  • Vt Andriole

    Hospital acquired urinary infections and the indwelling catheter

    Urol Clin North Am

    (1975)
  • Gf Thornton et al.

    Bacteriuria during indwelling catheter drainage. Effect of constant bladder rinse

    JAMA

    (1966)
  • Cited by (41)

    • Nosocomial Urinary Tract Infections

      2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
    • The resistance of polyvinylpyrrolidone-Iodine-poly(ε-caprolactone) blends to adherence of Escherichia coli

      2005, Biomaterials
      Citation Excerpt :

      Firstly, being a non-antibiotic, antimicrobial agent, the possibility of resistance developing due to the local release of this agent from medical devices is lower than for conventional antibiotics [9,16]. Secondly, there is a history of urological usage of PVP-I. For example, it has been shown that 2% PVP-I solutions can be successfully used as bladder irrigation washouts for the prevention of UTI associated with intermittent urethral catheterization [25]. The choice of concentration of PVP-I (1% w/w) for inclusion within the PCL films was performed according to ease of incorporation within PCL using solvent evaporation.

    • Povidone - Iodine

      1998, Analytical Profiles of Drug Substances and Excipients
    View all citing articles on Scopus
    View full text