Adult urologyClassification (traditional and national institutes of health) and demographics of prostatitis
Section snippets
Methods
Patient accrual for the CPC Study began on October 16, 1998. All 488 patients who had been successfully screened and enrolled into the CPC cohort before closing recruitment on August 22, 2001, were selected for this statistical analysis. The NIH-CPSI, including subscores, was used to measure symptoms. A comprehensive history, physical examination, and demographic profile were obtained from each participant. Generalized Mantel-Haenszel procedures were used to investigate baseline associations
Results
CP/CPPS is a chronic syndrome, affecting men over a wide age range. Most CPC Study participants are white, well educated, and affluent. However, lower education, lower income, and unemployment were associated with more severe CPPS symptoms. Patients most frequently reported pain in the perineum and tenderness in the prostate. The most common self-reported diseases were genitourinary (55%), allergic (53%), neurologic (40%), and hematopoietic, either lymphatic or infectious (40%). CP/CPPS has a
Conclusion
CP/CPPS is a multifactorial problem affecting men of all ages and demographics. Patients with CPPS have a dismal quality of life, and many have benefited only minimally from empiric, goal-directed therapy. Long-term follow-up study of this CPPS cohort will answer important questions about the natural and treated history of this syndrome.
Although men with CP routinely receive anti-inflammatory and antimicrobial therapy, we found that leukocyte and bacterial counts, as we defined them, do not
References (9)
- et al.
Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health chronic prostatitis symptom index
J Urol
(2001) - et al.
The National Institutes of Health chronic prostatitis symptom indexdevelopment and validation of a new outcome measure. Chronic Prostatitis Collaborative Research Network
J Urol
(1999) - et al.
Demographic and clinical characteristics of men with chronic prostatitisthe NIH Chronic Prostatitis Cohort (CPC) Study
J Urol
(2002) - et al.
Leukocyte and bacterial counts do not correlate with severity of symptoms in men with chronic prostatitisthe NIH Chronic Prostatitis Cohort (CPC) Study
J Urol
(2002)
Cited by (33)
Research of correlation between the amount of leukocyte in EPS and NIH-CPSI: Result from 1242 men in Fangchenggang Area in Guangxi Province
2012, UrologyCitation Excerpt :The diagnostic methods of CP are controversial at present. In clinical practice, many clinicians still use the count of leukocytes in EPS as a tool for assessment and diagnosis in men with CP, but the significance and clinical value of leukocyte count still fail to be clear.16 Further research found that there is no correlation between leukocyte counts in EPS and severity of symptoms of CP.
Interleukin 8 and Anti-Chlamydia trachomatis Mucosal IgA as Urogenital Immunologic Markers in Patients with C. trachomatis Prostatic Infection
2007, European UrologyCitation Excerpt :Chronic prostatitis (CP) has been described as one of the most common illnesses in men aged ≤50 yr [1], with different clinical presentations such as pelvic pain, lower urinary tract symptoms (LUTS), or sexual disfunction [2]. According to the classification of the National Institutes of Health (NIH) [3], class III chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most frequent category [4], where either genitourinary symptoms or pain are usually found, but no uropathogenic bacteria are detected by traditional methods [5]. This fact could be due either to the difficulty in identifying new microorganisms or to a substantial lack in the microbiologic methods used for the diagnosis [6].
Neuroaugmentation in the management of pelvic pain syndromes
2006, Techniques in Regional Anesthesia and Pain ManagementNeuromodulation of pelvic visceral pain: Review of the literature and case series of potential novel targets for treatment
2013, Pain PracticeCitation Excerpt :Despite likely being underreported secondary to the syndrome's vague constellation of bothersome symptoms (urinary frequency, dysuria, poor urinary flow, and genital or perineal pain), CP/PD still manages to make up a large portion of all cases of prostatitis.22 In the U.S. alone, approximately 25% of men presenting with genitourinary tract problems are diagnosed with prostatitis, and up to 30% of those are ultimately diagnosed with CP/PD.30, 31 PD has been considered a diagnosis of exclusion and a possible variant of IC as it may represent different manifestations of the same disease process.32