Elsevier

Urology

Volume 60, Issue 6, Supplement, December 2002, Pages 5-6
Urology

Adult urology
Classification (traditional and national institutes of health) and demographics of prostatitis

https://doi.org/10.1016/S0090-4295(02)02292-6Get rights and content

Abstract

This article reviews the National Institutes of Health (NIH) classification system for prostatitis and summarizes the baseline analysis of the Chronic Prostatitis Cohort Study, a longitudinal study, which has enrolled 488 patients diagnosed with category III prostatitis. The prevalence of category IIIA in this cohort was 54% to 90%, depending on the cut points used. In all, 8% (37 of 488) had ≥1 localizing uropathogen. However, leukocyte and bacterial counts did not correlate with severity of symptoms as assessed by the NIH Chronic Prostatitis Symptom Index. Continued follow-up study of this cohort will likely answer important questions about the natural and treated history of this syndrome.

Section snippets

Methods

Patient accrual for the CPC Study began on October 16, 1998. All 488 patients who had been successfully screened and enrolled into the CPC cohort before closing recruitment on August 22, 2001, were selected for this statistical analysis. The NIH-CPSI, including subscores, was used to measure symptoms. A comprehensive history, physical examination, and demographic profile were obtained from each participant. Generalized Mantel-Haenszel procedures were used to investigate baseline associations

Results

CP/CPPS is a chronic syndrome, affecting men over a wide age range. Most CPC Study participants are white, well educated, and affluent. However, lower education, lower income, and unemployment were associated with more severe CPPS symptoms. Patients most frequently reported pain in the perineum and tenderness in the prostate. The most common self-reported diseases were genitourinary (55%), allergic (53%), neurologic (40%), and hematopoietic, either lymphatic or infectious (40%). CP/CPPS has a

Conclusion

CP/CPPS is a multifactorial problem affecting men of all ages and demographics. Patients with CPPS have a dismal quality of life, and many have benefited only minimally from empiric, goal-directed therapy. Long-term follow-up study of this CPPS cohort will answer important questions about the natural and treated history of this syndrome.

Although men with CP routinely receive anti-inflammatory and antimicrobial therapy, we found that leukocyte and bacterial counts, as we defined them, do not

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