Prostatic Diseases and Male Voiding DysfunctionAre Lower Urinary Tract Symptoms Influenced by Metabolic Syndrome?
Section snippets
Study Cohort
During a 6-month period, all men aged 30-69 years and all women aged 40-69 years participating in a voluntary health examination in the area of Vienna were assessed regarding the prevalence of the MS and LUTS. The Department of Preventive Health of the City of Vienna regularly performs these examinations at 7 locations where citizens can undergo a health evaluation free of charge once annually. In addition, employees of large companies are invited to participate. The institutional review board
Principal Patient Characteristics
A cohort of 2371 men aged 30-69 years and 731 women aged 40-69 years was analyzed. The age distribution for the men was as follows: 30-39 years, n = 734 (31%); 40-49 years, n = 783 (33%); 50-59 years, n = 579 (24.4%); 60-69 years, n = 275 (11.6%). The age distribution for the women was as follows: 40-49 years, n = 256 (35%); 50-59 years, n = 250 (34.2%); and 60-69 years, n = 225 (30.8%). The descriptive data of age, IPSS, body mass index, and all numeric vascular risk factors in men and woman
Comment
The MS is a highly prevalent disorder of growing importance in Western societies and a well-established risk factor for atherosclerosis, including coronary heart disease, cerebral infarction, and peripheral arterial disease.4 The role of the MS as a risk factor for urologic disorders is less well defined. Our group has previously reported on the affect of the MS on erectile dysfunction and female sexual dysfunction.8, 9 In men, an increased waist-to-hip ratio and the presence of the MS were
Conclusions
Our data suggest that the MS is not associated with LUTS. Because these data were generated in a large cohort with a significant proportion of men and women with the MS and LUTS, we believe this conclusion is fairly robust.
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Cited by (46)
Metabolic syndrome and lower urinary tract symptoms in patients with benign prostatic enlargement: A possible link to storage symptoms
2014, UrologyCitation Excerpt :The presence of MetS increased, by about 80% (OR, 1.78; CI, 1.045-3.042; P = .03), the risk of having an IPSS subscore ≥4 in patients with LUTS and BPE. Most of the evidence available in the literature evaluating the association between LUTS and MetS are derived from epidemiologic studies from Asian or American populations.10,12,15,18 Analysis of the BACH survey18 showed a trend in increasing MetS prevalence with increasing American Urological Association Symptom Index (AUA-SI) scores.
Risk factors for male lower urinary tract symptoms: The role of metabolic syndrome and androgenetic alopecia in a Latin American population
2013, UrologyCitation Excerpt :This observation underscores the possibility of a BPH-independent association between MetS and LUTS, likely related to arterial insufficiency and ischemia of the bladder.6,26 A number of studies, in particular in Asian populations, did not find an association between male LUTS and the MetS.7-11 Differences between these results and ours could stem from several factors.
Metabolic syndrome associated with reduced lower urinary tract symptoms in middle-aged men receiving health checkup
2012, UrologyCitation Excerpt :Finally, the higher PV and PSA groups had increased total and individual IPSS item scores than the lower PV and PSA groups, which may magnify the beneficial effect of MS on LUTS. According to the findings of the present study, the association between BPH, LUTS, and MS components in men may be confounded by many factors, including age, PV, smoking, alcohol consumption, lifestyle, and others.4,8,9,19 To further clarify these relationships, all possible confounders should be adjusted for in subsequent studies.