Society of University SurgeonsFactors predicting failure to identify a sentinel lymph node in breast cancer
Section snippets
Methods
The University of Louisville Breast Cancer Sentinel Lymph Node study is a prospective multicenter study in which patients underwent SLN biopsy followed by planned completion level I/II axillary lymph node dissection. More than 300 surgeons participated in this study, many of whom had heretofore little to no experience with the technique of SLN biopsy. The technique of SLN biopsy in terms of injection material (blue dye and/or radioactive colloid) and injection site was left to the discretion of
Results
Between November 1996 and July 2004, 4131 patients enrolled. The median patient age was 60 years (range, 27-100 years). Clinicopathologic tumor features are shown in Table I.
Three-hundred thirty-six surgeons participated in this study. Many surgeons did not have extensive SLN biopsy experience before participating in this study. The median number of SLN procedures performed by each surgeon in this study was 9 (range, 1-89). Type of biopsy for diagnosis, choice of operative procedure, and
Discussion
While SLN biopsy was designed to avoid the unnecessary morbidity of an axillary node dissection in node-negative patients,3, 4, 5, 6, 7 the success of SLN biopsy requires that surgeons be able to identify an SLN. A number of studies have demonstrated variable identification rates for this procedure, ranging from 64% to 100%, depending on surgeon experience and technique (Table VI).8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37
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2022, Clinical Breast CancerIdentification of sentinel lymph node: Comparison between SNOLL and routine isotopic procedure
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2016, Gynecologie Obstetrique et Fertilite
Presented at the 66th Annual Meeting of the Society of University Surgeons, Nashville, Tennessee, February 9-12, 2005.
Supported by Center for Advanced Surgical Technologies (CAST) of Norton Hospital, Louisville, KY.