Original articleOutcomes of Bilateral Cataracts Removed in Infants 1 to 7 Months of Age Using the Toddler Aphakia and Pseudophakia Treatment Study Registry
Section snippets
Methods
This study was approved by the institutional review board or ethics review board at all participating institutions (Mayo Clinic, University of Minnesota, Medical University of South Carolina, Harvard University, Indiana University Medical Center, Duke University Medical Center, Cleveland Clinic, Oregon Health and Science University, Baylor College of Medicine and Texas Children’s Hospital, Emory University School of Medicine, Vanderbilt University Medical Center) and complied with the Health
Results
A total of 164 children (311 eyes) with a history of bilateral cataract surgery before 2 years of age and with a surgical date between 2004 and 2010 (the years of the IATS recruitment) were registered into the TAPS by 10 IATS sites. Two of the original 12 IATS clinical sites did not participate because of institutional review board limitations. Both eyes were enrolled in 147 patients. In 17 patients, only 1 eye was enrolled because the cataract surgery on the fellow eye was performed outside of
Discussion
The TAPS is a large registry of unilateral and bilateral cataracts in children undergoing surgery from 1 to 24 months of age.17 Despite the limitations of retrospective data analysis, the TAPS cataract surgery outcome data are informative and important because these procedures were performed by IATS surgeons during the same period as the IATS and provide comparisons that can guide clinical practice. This case series is the first TAPS study on bilateral cataract outcomes and involves children 1
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Cited by (0)
Supplemental material available at www.aaojournal.org.
Financial Disclosure(s): The author(s) have made the following disclosure(s): M.E.W.: Financial support – Knights Templar.
D.K.V.: Financial support – Knights Templar.
D.A.P.: Financial support – Knights Templar.
S.F.F.: Financial support – Knights Templar.
E.I.T.: Financial support – Knights Templar.
J.S.A.: Financial support – Knights Templar.
A.R.L.: Financial support – Knights Templar.
N.C.W.: Financial support – Knights Templar.
D.M.: Financial support – Knights Templar.
S.R.L.: Financial support – Knights Templar.
Supported by the Mayo Clinic, Rochester, Minnesota (CCaTS grant no.: UL1TR000135). The sponsor or funding organization had no role in the design or conduct of this research.
HUMAN SUBJECTS: The human ethics committees at all participating institutions approved the study (Mayo Clinic, University of Minnesota, Medical University of South Carolina, Harvard University, Indiana University Medical Center, Duke University Medical Center, Cleveland Clinic, Oregon Health and Science University, Baylor College of Medicine and Texas Children’s Hospital, Emory University School of Medicine, Vanderbilt University Medical Center). All research complied with the Health Insurance Portability and Accountability (HIPAA) Act. Data sharing agreements were established between IATS investigator site and the Mayo Clinic. As a retrospective chart review, informed consent was not required by the IRBs.
No animal subjects were included in this study.
Author Contributions:
Conception and design: Bothun, Wilson, Vanderveen, Plager, Freedman, Trivedi, Traboulsi, Anderson, Loh, Yen, Weil, Morrison, Lambert
Analysis and interpretation: Bothun, Wilson, Vanderveen, Plager, Freedman, Trivedi, Traboulsi, Anderson, Loh, Yen, Weil, Morrison, Lambert
Data collection: Bothun, Wilson, Vanderveen, Plager, Freedman, Trivedi, Traboulsi, Anderson, Loh, Yen, Weil, Morrison, Lambert
Obtained funding: Wilson, Vanderveen, Plager, Freedman, Traboulsi, Anderson, Loh, Weil, Morrison, Lambert
Overall responsibility: Bothun, Wilson, Vanderveen, Plager, Freedman, Trivedi, Traboulsi, Anderson, Loh, Yen, Weil, Morrison, Lambert