Original articleDry Eye Disease after Refractive Surgery: Comparative Outcomes of Small Incision Lenticule Extraction versus LASIK
Section snippets
Methods
This prospective, comparative, nonrandomized clinical study was conducted in the Clinical Center for Investigation of Ocular Surface Pathology (Quinze-Vingts National Ophthalmology Hospital, National Institute for Health and Medical Research 503, Paris, France) in accordance with the Declaration of Helsinki, Scotland amendment, 2000. Previous approval was obtained from the National Ethical Research Committee (Comité de Protection des Personnes Ile de France V, National Agreement Number 10793).
Results
No adverse effects occurred in any of the 120 procedures. Six-month postoperative best-uncorrected visual acuity and residual spherical equivalent were not statistically different between SMILE and LASIK eyes, as detailed in Table 1. Morphologic parameters including the keratometry, epithelial thickness, and total thickness of the cornea, and the mean depth of the interface, as assessed by OCT, did not differ between the 2 groups.
Discussion
Dry eye is still the most frequent complication of refractive surgery.14 Post-refractive dry eye disease is an immediate issue because the patients' visual comfort and quality of life dictate their overall satisfaction.15 On a more global scale, ocular dryness after refractive surgery may lead to permanent pain, visual fluctuations, and the need for daily treatment, which affects health status, quality of life, and vision when it lasts for months or even years. New corneal procedures, such as
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Financial Disclosure(s): The author(s) have made the following disclosure(s):
A.D.: Consultant – Alcon, Thea, Abbott Medical Optics, Bausch & Lomb; Grants/grants pending – INSERM and UPMC University Paris 6; Inventor – 2 patents belonging to INSERM. C.B.: Board member and consultant – Alcon, Allergan, MSD, Thea, Santen; grants/grants pending – Allergan, MSD, Thea, Santen; Co-inventor – 2 patents belong to INSERM.
Public grant from the French National Institute of Health and Medical Research. The funding organization had no role in the design or conduct of this research.